John A. Kellum: Writing – review & editing, Writing – original draft, Supervision, Project administration, Methodology, Investigation, Funding acquisition, Conceptualization. Sean M. Bagshaw: Writing – review & editing, Methodology, Investigation, Conceptualization. Sevag Demirjian: Writing – review & editing, Investigation, Conceptualization. Lui Forni: Writing – review & editing, Methodology, Investigation. Michael Joannidis: Writing – review & editing, Investigation, Conceptualization. J.