Frat JP, Thille AW, Mercat A, Girault C, Ragot S, Perbet S, Prat G, Boulain T, Morawiec E, Cottereau A, Devaquet J, Nseir S, Razazi K, Mira JP, Argaud L, Chakarian JC, Ricard JD, Wittebole FLORALS Study Group; REVA Network (2015) High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med 372(23):2185–2196. https://doi.org/10.1056/NEJMoa1503326

Article  CAS  PubMed  Google Scholar 

Bräunlich J, Köhler M, Wirtz H (2016) Nasal highflow improves ventilation in patients with COPD. Int J Chron Obstruct Pulmon Dis 11:1077–1085. https://doi.org/10.2147/COPD.S104616

Article  PubMed  PubMed Central  Google Scholar 

Vargas F, Saint-Leger M, Boyer A, Bui NH, Hilbert G (2015) Physiologic effects of high-flow nasal cannula oxygen in critical care subjects. Breathe Care 60(10):1369–1376. https://doi.org/10.4187/respcare.03814

Article  Google Scholar 

Mauri T, Turrini C, Eronia N, Grasselli G, Volta CA, Bellani G, Pesenti A (2017) Physiologic effects of high-flow nasal cannula in acute hypoxemic respiratory failure. Am J Respir Crit Care Med 195(9):1207–1215. https://doi.org/10.1164/rccm.201605-0916OC

Article  PubMed  Google Scholar 

Grieco DL, Maggiore SM, Roca O, Spinelli E, Patel BK, Thille AW, Barbas CSV, de Acilu MG, Cutuli SL, Bongiovanni F, Amato M, Frat JP, Mauri T, Kress JP, Mancebo J, Antonelli M (2021) Non -invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS. Intensive Care Med 47(8):851–866. https://doi.org/10.1007/s00134-021-06459-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tonelli R, Fantini R, Bruzzi G et al (2023) Effect of high flow nasal oxygen on inspiratory effort of patients with acute hypoxic respiratory failure and do not intubate orders. Intern Emerg Med. https://doi.org/10.1007/s11739-023-03471-w