Advances in Pharmacology and Pharmacy Vol. 12(3), pp. 256 - 263
DOI: 10.13189/app.2024.120310
Reprint (PDF) (492Kb)

Neeraj Kumar 1, Priyanka Sharma 1, S. C. Joshi 2, Utkarsh Kaushik 3,*
1 Department of Zoology, Lord University, Alwar, Rajasthan, India
2 President, Lord University, Rajasthan, India
3 Department of Zoology, Poddar International College, Jaipur, Rajasthan, India

ABSTRACT

Pesticides are the most commonly used substances these days. Pesticides are chemicals that are used to combat toxins that reduce agricultural output. Concerns have been expressed, nevertheless, about its potential negative effects on the ability of both humans and wildlife to reproduce. Pesticides and insecticides are classified into numerous groups. Organophosphates are commonly used pesticides. In order to better understand the mechanisms, exposure pathways, and potential dangers of profenofos and its reproductive toxicity, the goal of this in-depth review is to synthesize the available evidence. Organophosphate insecticides produce a variety of problems in mammals, including physiological, reproductive, and other malformations. The review includes a critical analysis of epidemiological and experimental studies that looked into Profenofos' effects on human and animal reproduction. It draws attention to the possible dangers of exposure to profenofos, including decreased fertility, aberrant development, and poor pregnancy outcomes. In this review, we will focus on Profenofos, which causes reproductive toxicity in the reproductive system of rats, such as decreased testicular size, decreased sperm generation, loss of gametogenesis hormone activity, and effects on the seminiferous tubules, among several others. The article provides a thorough analysis of profenofos and its reproductive toxicity, synthesizing the available research to increase public knowledge of the possible dangers of its use.

KEYWORDS
Pesticides, Organophosphates, Profenofos, Reproductive Toxicity

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Neeraj Kumar , Priyanka Sharma , S. C. Joshi , Utkarsh Kaushik , "A Review on Profenofos and its Reproductive Toxicity," Advances in Pharmacology and Pharmacy, Vol. 12, No. 3, pp. 256 - 263, 2024. DOI: 10.13189/app.2024.120310.

(b). APA Format:
Neeraj Kumar , Priyanka Sharma , S. C. Joshi , Utkarsh Kaushik (2024). A Review on Profenofos and its Reproductive Toxicity. Advances in Pharmacology and Pharmacy, 12(3), 256 - 263. DOI: 10.13189/app.2024.120310.