Aim This multicenter, randomized controlled trial evaluated the efficacy of the Lumoral® dual-light antibacterial photodynamic (aPDT) home care device as an adjunct tool to non-surgical periodontal treatment (NSPT) in chronic periodontitis patients.

Materials and Methods Forty-one Stage I-III periodontitis patients were randomized to receive NSPT, including standardized hygiene instructions and scaling and root planing, or NSPT with adjunctive Lumoral® treatment, applied daily at home. Clinical examinations were conducted at baseline, three months, and six months.

Results Both groups showed significant reductions in Visual Plaque Index (VPI) and Bleeding on Probing (BOP) at three and six months. However, the NSPT + Lumoral® group exhibited significantly greater BOP and VPI reductions at six months (p=0.03, p=0.04) compared to the NSPT group. Incidence of Probing Pocket Depth (PPD) ≥ 4 mm reduced significantly in the NSPT + Lumoral® group at both follow-ups (p=0.0019, p=0.0043) but not in the NSPT group. Periodontal epithelial surface area (PESA) and periodontal inflamed surface area (PISA) significantly decreased in the NSPT + Lumoral® group (p<0.01), while no significant changes were observed in the control group.

Conclusion Regular adjunctive use of Lumoral® after NSPT resulted in improved clinical periodontitis treatment outcomes.

Tommi Patila owns stocks in Koite Health

ClinicalTrials.gov Identifier: NCT05425784

Koite Health provided the devices used in the study.

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

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The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Th ethics committee of Hospital District of Helsinki and Uusimaa gaveethical approval for this work

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All data produced in the present study are available upon reasonable request to the authors