Wang W, Wei PL, Lee YC, Huang MT, Chiu CC, Lee WJ. Short-term results of laparoscopic mini-gastric bypass. Obes Surg. 2005;15:648–54. https://doi.org/10.1381/0960892053923752.

Article  PubMed  Google Scholar 

Abdelaal M, Le Roux CW, Docherty NG. Morbidity and mortality associated with obesity. Ann Transl Med. 2017;5:161. https://doi.org/10.21037/atm.2017.03.107.

Article  PubMed  PubMed Central  Google Scholar 

Obesity: preventing and managing the global epidemic. Report of a WHO consultation. (2000) World Health Organ Tech Rep Ser.; 894:i-xii, 1-253. PMID: 11234459.

Bowman K, Atkins JL, Delgado J, Kos K, Kuchel GA, Ble A, Ferrucci L, Melzer D. Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants. Am J Clin. Nutr. 2017;106:130–5. https://doi.org/10.3945/ajcn.116.147157.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vyas V, Lambiase P. Obesity and Atrial Fibrillation: Epidemiology, Pathophysiology and Novel Therapeutic Opportunities. Arrhythm Electrophysiol Rev. 2019;8:28–36. https://doi.org/10.15420/aer.2018.76.2.

Article  PubMed  PubMed Central  Google Scholar 

Huxley RR, Lopez FL, Folsom AR, Agarwal SK, Loehr LR, Soliman EZ, Maclehose R, Konety S, Alonso A. Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the atherosclerosis risk in communities (ARIC) study. Circulation. 2011;123:1501–8. https://doi.org/10.1161/CIRCULATIONAHA.110.009035.

Article  PubMed  PubMed Central  Google Scholar 

Foy AJ, Mandrola J, Liu G, Naccarelli GV. Relation of Obesity to New-Onset Atrial Fibrillation and Atrial Flutter in Adults. Am J Cardiol. 2018;121:1072–5. https://doi.org/10.1016/j.amjcard.2018.01.019.

Article  PubMed  Google Scholar 

Wang TJ, Parise H, Levy D, D’Agostino RB, Wolf PA, Vasan RS, Benjamin EJ. Obesity and the risk of new-onset atrial fibrillation. JAMA. 2004;292:2471–7. https://doi.org/10.1001/jama.292.20.2471.

Article  CAS  PubMed  Google Scholar 

Wong CX, Sullivan T, Sun MT, Mahajan R, Pathak RK, Middeldorp M, Twomey D, Ganesan AN, Rangnekar G, Roberts-Thomson KC, Lau DH, Sanders P. Obesity and the risk of incident, post-operative, and post-ablation atrial fibrillation: a meta-analysis of 626,603 individuals in 51 studies. JACC Clin Electrophysiol. 2015;1:139–52. https://doi.org/10.1016/j.jacep.2015.04.004.

Article  PubMed  Google Scholar 

Krijthe BP, Kunst A, Benjamin EJ, Lip GYH, Franco OH, Hofman A, Witteman JCM, Stricker BH, Heeringa J. Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. Eur Heart J. 2013;34:2746–51. https://doi.org/10.1093/eurheartj/eht280.

Article  PubMed  PubMed Central  Google Scholar 

Lee H, Choi EK, Lee SH, Han KD, Rhee TM, Park CS, Lee SR, Choe WS, Lim WH, Kang SH, Cha M-J, Oh S. Atrial fibrillation risk in metabolically healthy obesity: a nationwide population-based study. Int J Cardiol. 2017;240:221–7. https://doi.org/10.1016/j.ijcard.2017.03.103.

Article  PubMed  Google Scholar 

Cho B-H, Cheon K, Lee KY, Jung YH, Han SW, Park JH, Choi H-Y, Cho HJ, Park HJ, Nam HS, Heo JH, Lee HS, Kim S, Kim YD. Association between body mass index and stroke severity in acute ischaemic stroke with non-valvular atrial fibrillation. Eur J Neurol. 2020;27:1672–9. https://doi.org/10.1111/ene.14304.

Article  PubMed  Google Scholar 

Wanahita N, Messerli FH, Bangalore S, Gami AS, Somers VK, Steinberg JS. Atrial fibrillation and obesity--results of a meta-analysis. Am Heart J. 2008;155:310–5. https://doi.org/10.1016/j.ahj.2007.10.004.

Article  PubMed  Google Scholar 

Frey WC, Pilcher J. Obstructive sleep-related breathing disorders in patients evaluated for bariatric surgery. Obes Surg. 2003;13:676–83. https://doi.org/10.1381/096089203322509228.

Article  PubMed  Google Scholar 

Qu YC, Du YM, Wu SL, Chen QX, Wu HL, Zhou SF. Activated nuclear factor-kappaB and increased tumor necrosis factor-alpha in atrial tissue of atrial fibrillation. ScandCardiovasc J. 2009;43:292–7. https://doi.org/10.1080/14017430802651803.

Article  CAS  Google Scholar 

Venteclef N, Guglielmi V, Balse E, Gaborit B, Cotillard A, Atassi F, Amour J, Leprince P, Dutour A, Clément K, Hatem SN. Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines. Eur Heart J. 2015;36:795–805a. https://doi.org/10.1093/eurheartj/eht099.

Article  CAS  PubMed  Google Scholar 

Balcioğlu AS, Çiçek D, Akinci S, Eldem HO, Bal UA, Okyay K, Müderrisoğlu H. Arrhythmogenic evidence for epicardial adipose tissue: heart rate variability and turbulence are influenced by epicardial fat thickness. Pacing Clin Electrophysiol. 2015;38:99e106. https://doi.org/10.1111/pace.12512.

Article  Google Scholar 

Al Chekakie MO, Welles CC, Metoyer R, Ibrahim A, Shapira AR, Cytron J, Santucci P, Wilber DJ, Akar JG. Pericardial fat is independently associated with human atrial fibrillation. J Am CollCardiol. 2010;56:784–8. https://doi.org/10.1016/j.jacc.2010.03.071.

Article  Google Scholar 

Martin K, Beyer-Westendorf J, Davidson BL, Huisman MV, Sandset PM, Moll S. Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH. J ThrombHaemost. 2016;14:1308–13. https://doi.org/10.1111/jth.13323.

Article  CAS  Google Scholar 

Yu L, Scherlag BJ, Sha Y, Li S, Sharma T, Nakagawa H, Jackman WM, Lazzara R, Jiang H, Po SS. Interactions between atrial electrical remodelling and autonomic remodelling: How to break the vicious cycle. Heart Rhythm. 2012;9:804–9. https://doi.org/10.1016/j.hrthm.2011.12.023.

Article  PubMed  Google Scholar 

Kaplan RM, Diaz CL, Strzelczyk T, You C, Saour B, Fine M, Trivedi A, Shen MJ, Sattayaprasert P, Chicos AB, Arora R, Kim S, Lin A, Verma N, Knight BP, Passman RS. Outcomes with novel oral anticoagulants in obese patients who underwent electrical cardioversion for atrial arrhythmias. Am J Cardiol. 2018;122:1175–8. https://doi.org/10.1016/j.amjcard.2018.06.022.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thangjui S, Kewcharoen J, Yodsuwan R, Trongtorsak A, Thyagaturu H, Shrestha B, Winans ARM, Bischof E (2021) Efficacy and safety of direct oral anticoagulant in morbidly obese patients with atrial fibrillation: systematic review and meta-analysis. Eur Heart J Cardiovasc Pharmacother.; pvab026. https://doi.org/10.1093/ehjcvp/pvab026.

Xue Y, Xu X, Zhang XQ, Farokhzad OM, Langer R. Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles. Proc Natl AcadSci USA. 2016;113:5552–7. https://doi.org/10.1073/pnas.1603840113.

Article  CAS  Google Scholar 

Iacobellis G, Mohseni M, Bianco SD, Banga PK. Liraglutide causes large and rapid epicardial fat reduction. Obesity. 2017;25:311–6. https://doi.org/10.1002/oby.21718.

Article  CAS  PubMed  Google Scholar 

Sato T, Aizawa Y, Yuasa S, Kishi S, Fuse K, Fujita S, Ikeda Y, Kitazawa H, Takahashi M, Sato M, Okabe M. The effect of dapagliflozin treatment on epicardial adipose tissue volume. Cardiovasc Diabetol. 2018;17:6. https://doi.org/10.1186/s12933-017-0658-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chung MK, Eckhardt LL, Chen LY, Ahmed HM, Gopinathannair R, Joglar JA, Noseworthy PA, Pack QR, Sanders P, Trulock KM. Lifestyle and Risk Factor Modification for Reduction of Atrial Fibrillation: A Scientific Statement From the American Heart Association. Circulation. 2020;141:e750–72. https://doi.org/10.1161/CIR.0000000000000748.

Article  PubMed  Google Scholar 

Pathak RK, Elliott A, Middeldorp ME, Meredith M, Mehta AB, Mahajan R, Hendriks JML, Twomey D, Kalman JM, Abhayaratna WP, Lau DH, Sanders P. Impact of CARDIOrespiratoryFITness on arrhythmia recurrence in obese individuals with atrial fibrillation: the CARDIO-FIT study. J Am CollCardiol. 2015;66:985–96. https://doi.org/10.1016/j.jacc.2015.06.488.

Article  Google Scholar 

Qureshi WT, Alirhayim Z, Blaha MJ, Juraschek SP, Keteyian SJ, Brawner CA, Al-Mallah MH. Cardiorespiratory fitness and risk of incident atrial fibrillation: results from the Henry ford exercise testing (FIT) project. Circulation. 2015;131:1827–34. https://doi.org/10.1161/CIRCULATIONAHA.114.014833.

Article  PubMed  Google Scholar 

Jamaly S, Carlsson L, Peltonen M, Jacobson P, Sjöström L, Karason K. Bariatric surgery and the risk of new-onset atrial fibrillation in Swedish obese subjects. J Am Coll Cardiol. 2016;68:2497–504. https://doi.org/10.1016/j.jacc.2016.09.940.

Article  PubMed  PubMed Central  Google Scholar 

Donnellan E, Wazni OM, Kanj M, Baranowski B, Cremer P, Harb S, McCarthy CP, McEvoy JW, Elshazly MB, Aagaard P, Tarakji KG, Jaber WA, Schauer PR, Saliba WI. Association between pre-ablation bariatric surgery and atrial fibrillation recurrence in morbidly obese patients undergoing atrial fibrillation ablation. Europace. 2019;21:1476–83. https://doi.org/10.1093/europace/euz183.

Article  PubMed  Google Scholar 

Lévy S, Lauribe P, Dolla E, Kou W, Kadish A, Calkins H, Pagannelli F, Moyal C, Bremondy M, Schork A. A randomized comparison of external and internal cardioversion of chronic atrial fibrillation. Circulation. 1992;86:1415–20. https://doi.org/10.1161/01.CIR.86.5.1415.

Article  PubMed  Google Scholar 

Voskoboinik A, Moskovitch J, Plunkett G, Bloom J, Wong G, Nalliah C, Prabhu S, Sugumar H, Paramasweran R, McLellan A, Ling LH, Goh CY, Noaman S, Fernando H, Wong M, Taylor AJ, Kalman JM, Kistler PM. Cardioversion of atrial fibrillation in obese patients: Results from the Cardioversion-BMI randomized controlled trial. J Cardiovasc Electrophysiol. 2019;30:155–61. https://doi.org/10.1111/jce.13786.

Article  PubMed  Google Scholar 

Boehmer AA, Rothe M, Nussbaum E, Ruckes C, Dobre BC, Kaess BM, Ehrlich JR. Cryoballoon pulmonary vein isolation for atrial fibrillation in obese patients: A non-inferiority analysis. Int J Cardiol Heart Vasc. 2023;47:101244.

PubMed  PubMed Central  Google Scholar 

Cha YM, Friedman PA, Asirvatham SJ, Shen WK, Munger TM, Rea RF, Brady PA, Jahangir A, Monahan KH, Hodge DO, Meverden RA, Gersh BJ, Hammill SC, Packer DL. Catheter ablation for atrial fibrillation in patients with obesity. Circulation. 2008;117:2583–90.

Article  PubMed  Google Scholar 

Lakkireddy DR, Blake GE, Patel D, Rotter M, Verma A, Ryschon K, Khan M, Schweikert R, Haissaguerre M, Natale A. Success of Radiofrequency Catheter Ablation of Atrial Fibrillation: Does Obesity Influence the Outcomes? J Atr Fibrillation. 2008;1:36.