Aldana-Masangkay GI, Sakamoto KM (2011) The role of HDAC6 in cancer. BioMed Res Int 2011:875824. https://doi.org/10.1155/2011/875824

Article  CAS  Google Scholar 

Baek J-H (2019) The impact of versatile macrophage functions on acute kidney injury and its outcomes. Front Physiol 10:1016. https://doi.org/10.3389/fphys.2019.01016

Article  PubMed  PubMed Central  Google Scholar 

Berl T, Henrich W (2006) Kidney-heart interactions: epidemiology, pathogenesis, and treatment. Clin J Am Soc Nephrol 1:8–18. https://doi.org/10.2215/CJN.00730805

Article  CAS  PubMed  Google Scholar 

Bhargava P, Schnellmann RG (2017) Mitochondrial energetics in the kidney. Nat Rev Nephrol 13:629–646. https://doi.org/10.1038/nrneph.2017.107

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cao Q, Wang Y, Wang XM, Lu J, Lee VW, Ye Q, Nguyen H, Zheng G, Zhao Y, Alexander SI, Harris DCH (2015) Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy. J Am Soc Nephrol: JASN 26:349. https://doi.org/10.1681/ASN.2013121336

Article  CAS  PubMed  Google Scholar 

Chen X, Yu C, Hou X, Li J, Li T, Qiu A, Liu N, Zhuang S (2020) Histone deacetylase 6 inhibition mitigates renal fibrosis by suppressing TGF-β and EGFR signaling pathways in obstructive nephropathy. Am J Physiol Renal Physiol 319:F1003–F1014. https://doi.org/10.1152/ajprenal.00261.2020

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cho E, Kim M, Ko YS, Lee HY, Song M, Kim MG, Kim H-K, Cho W-Y, Jo S-K (2013) Role of inflammation in the pathogenesis of cardiorenal syndrome in a rat myocardial infarction model. Nephrol Dial Transplant 28:2766–2778. https://doi.org/10.1093/ndt/gft376

Article  CAS  PubMed  Google Scholar 

Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu F-T, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ (2013) Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis 207:947–956. https://doi.org/10.1093/infdis/jis920

Article  CAS  PubMed  Google Scholar 

Clementi A, Virzì GM, Battaglia GG, Ronco C (2019) Neurohormonal, endocrine, and immune dysregulation and inflammation in cardiorenal syndrome. Cardiorenal Med 9:265–273. https://doi.org/10.1159/000500715

Article  CAS  PubMed  Google Scholar 

Costanzo MR (2022) The cardiorenal syndrome in heart failure. Cardiol Clin 40:219–235. https://doi.org/10.1016/j.ccl.2021.12.010

Article  PubMed  Google Scholar 

Demos-Davies KM, Ferguson BS, Cavasin MA, Mahaffey JH, Williams SM, Spiltoir JI, Schuetze KB, Horn TR, Chen B, Ferrara C, Scellini B, Piroddi N, Tesi C, Poggesi C, Jeong MY, McKinsey TA (2014) HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling. Am J Physiol Heart Circ Physiol 307:H252–H258. https://doi.org/10.1152/ajpheart.00149.2014

Article  CAS  PubMed  PubMed Central  Google Scholar 

Di Lullo L, Bellasi A, Barbera V, Russo D, Russo L, Di Iorio B, Cozzolino M, Ronco C (2017) Pathophysiology of the cardio-renal syndromes types 1–5: an uptodate. Indian Heart J 69:255–265. https://doi.org/10.1016/j.ihj.2017.01.005

Article  PubMed  PubMed Central  Google Scholar 

Dikow R, Adamczak M, Henriquez DE, Ritz E (2002) Strategies to decrease cardiovascular mortality in patients with end-stage renal disease. Kidney Int 61:S5–S10. https://doi.org/10.1046/j.1523-1755.61.s80.3.x

Article  Google Scholar 

Duffield JS (2010) Macrophages and immunologic inflammation of the kidney. Semin Nephrol 30:234–254. https://doi.org/10.1016/j.semnephrol.2010.03.003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Epelman S, Lavine KJ, Beaudin AE, Sojka DK, Carrero JA, Calderon B, Brija T, Gautier EL, Ivanov S, Satpathy AT, Schilling JD, Schwendener R, Sergin I, Razani B, Forsberg EC, Yokoyama WM, Unanue ER, Colonna M, Randolph GJ, Mann DL (2014) Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 40:91–104. https://doi.org/10.1016/j.immuni.2013.11.019

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gairola S, Ram C, Syed AM, Doye P, Kulhari U, Mugale MN, Murty US, Sahu BD (2021) Nootkatone confers antifibrotic effect by regulating the TGF-β/Smad signaling pathway in mouse model of unilateral ureteral obstruction. Eur J Pharmacol 910:174479. https://doi.org/10.1016/j.ejphar.2021.174479

Article  CAS  PubMed  Google Scholar 

Gajjala PR, Sanati M, Jankowski J (2015) Cellular and molecular mechanisms of chronic kidney disease with diabetes mellitus and cardiovascular diseases as its comorbidities. Front Immunol 6:340. https://doi.org/10.3389/fimmu.2015.00340

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ham O, Jin W, Lei L, Huang HH, Tsuji K, Huang M, Roh J, Rosenzweig A, Lu HAJ (2018) Pathological cardiac remodeling occurs early in CKD mice from unilateral urinary obstruction, and is attenuated by Enalapril. Sci Rep 8:16087. https://doi.org/10.1038/s41598-018-34216-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heidt T, Courties G, Dutta P, Sager HB, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M (2014) Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction. Circ Res 115:284–295. https://doi.org/10.1161/CIRCRESAHA.115.303567

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henderson NC, Mackinnon AC, Farnworth SL, Kipari T, Haslett C, Iredale JP, Liu F-T, Hughes J, Sethi T (2008) Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol 172:288–298. https://doi.org/10.2353/ajpath.2008.070726

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herzog CA, Asinger RW, Berger AK, Charytan DM, Díez J, Hart RG, Eckardt K-U, Kasiske BL, McCullough PA, Passman RS, DeLoach SS, Pun PH, Ritz E (2011) Cardiovascular disease in chronic kidney disease. A clinical update from kidney disease: improving global outcomes (KDIGO). Kidney Int 80:572–586. https://doi.org/10.1038/ki.2011.223

Article  PubMed  Google Scholar 

Hewitson TD, Holt SG, Smith ER (2015) Animal models to study links between cardiovascular disease and renal failure and their relevance to human pathology. Front Immunol 6:465. https://doi.org/10.3389/fimmu.2015.00465

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hof A, Geißen S, Singgih K, Mollenhauer M, Winkels H, Benzing T, Baldus S, Hoyer FF (2022) Myeloid leukocytes’ diverse effects on cardiovascular and systemic inflammation in chronic kidney disease. Basic Res Cardiol 117:38. https://doi.org/10.1007/s00395-022-00945-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M (2018) Cardiac macrophages promote diastolic dysfunction. J Exp Med 215:423–440. https://doi.org/10.1084/jem.20171274

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kee HJ, Bae EH, Park S, Lee KE, Suh SH, Kim SW, Jeong MH (2013) HDAC inhibition suppresses cardiac hypertrophy and fibrosis in DOCA-salt hypertensive rats via regulation of HDAC6/HDAC8 enzyme activity. Kidney Blood Press Res 37:229–239. https://doi.org/10.1159/000350148

Article  CAS  PubMed  Google Scholar 

Laroumanie F, Douin-Echinard V, Pozzo J, Lairez O, Tortosa F, Vinel C, Delage C, Calise D, Dutaur M, Parini A, Pizzinat N (2014) CD4+ T cells promote the transition from hypertrophy to heart failure during chronic pressure overload. Circulation 129:2111–2124. https://doi.org/10.1161/CIRCULATIONAHA.113.007101

Article  CAS  PubMed  Google Scholar 

Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA (2011) Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol 51:41–50. https://doi.org/10.1016/j.yjmcc.2011.04.005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leucker TM, Nomura Y, Kim JH, Bhatta A, Wang V, Wecker A, Jandu S, Santhanam L, Berkowitz D, Romer L, Pandey D (2017) Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6. Am J Physiol Heart Circ Physiol 312:H711–H720. https://doi.org/10.1152/ajpheart.00724.2016

Article  PubMed  PubMed Central  Google Scholar 

Li L, Liu F, Huang W, Wang J, Wan Y, Li M, Pang Y, Yin Z (2019) Ricolinostat (ACY-1215) inhibits VEGF expression via PI3K/AKT pathway and promotes apoptosis in osteoarthritic osteoblasts. Biomed Pharmacother 118:109357. https://doi.org/10.1016/j.biopha.2019.109357

Article  CAS  PubMed  Google Scholar 

Liu H (2021) The roles of histone deacetylases in kidney development and disease. Clin Exp Nephrol 25:215–223. https://doi.org/10.1007/s10157-020-01995-5

Article  CAS  PubMed  PubMed Central