Genetics of suicide ideation. A role for inflammation and neuroplasticity?

World Health Organization (2021) Suicide worldwide in 2019 Global Health Estimates’, Geneva

Doran CM, Kinchin I (2020) Economic and epidemiological impact of youth suicide in countries with the highest human development index. PLoS One. https://doi.org/10.1371/journal.pone.0232940

Article  PubMed  PubMed Central  Google Scholar 

Walsh EH, McMahon J, Herring MP (2022) Research review: the effect of school-based suicide prevention on suicidal ideation and suicide attempts and the role of intervention and contextual factors among adolescents: a meta-analysis and meta-regression. J Child Psychol Psychiatry Alli Discip 63(8):836–845. https://doi.org/10.1111/jcpp.13598

Article  Google Scholar 

Doupnik SK et al (2020) Association of suicide prevention interventions with subsequent suicide attempts, linkage to follow-up care, and depression symptoms for acute care settings: a systematic review and meta-analysis. JAMA Psychiatry 77(10):1021–1030. https://doi.org/10.1001/jamapsychiatry.2020.1586

Article  PubMed  Google Scholar 

Inagaki M et al (2015) Interventions to prevent repeat suicidal behavior in patients admitted to an emergency department for a suicide attempt: a meta-analysis’. J Affect Disord 175:66–78. https://doi.org/10.1016/j.jad.2014.12.048

Article  PubMed  Google Scholar 

Hill NTM et al (2020) Association of suicidal behavior with exposure to suicide and suicide attempt: a systematic review and multilevel meta-analysis. PLoS Med. https://doi.org/10.1371/JOURNAL.PMED.1003074

Article  PubMed  PubMed Central  Google Scholar 

Ribeiro JD et al (2016) Self-injurious thoughts and behaviors as risk factors for future suicide ideation, attempts, and death: a meta-analysis of longitudinal studies. Psychol Med 46(2):225–236. https://doi.org/10.1017/S0033291715001804

Article  CAS  PubMed  Google Scholar 

Klonsky ED, May AM, Saffer BY (2016) Suicide, suicide attempts, and suicidal ideation. Annu Rev Clin Psychol 12:307–330. https://doi.org/10.1146/annurev-clinpsy-021815-093204

Article  PubMed  Google Scholar 

Fazel S, Runeson B (2020) Suicide. N Engl J Med 382(3):266–274. https://doi.org/10.1056/NEJMra1902944

Article  PubMed  PubMed Central  Google Scholar 

Hubers AAM et al (2018) Suicidal ideation and subsequent completed suicide in both psychiatric and non-psychiatric populations: a meta-analysis. Epidemiol Psychiatr Sci 27(2):186–198. https://doi.org/10.1017/S2045796016001049

Article  CAS  PubMed  Google Scholar 

Yates K et al (2019) Association of psychotic experiences with subsequent risk of suicidal ideation, suicide attempts, and suicide deaths: a systematic review and meta-analysis of longitudinal population studies. JAMA Psychiatry 76(2):180–189. https://doi.org/10.1001/jamapsychiatry.2018.3514

Article  PubMed  Google Scholar 

Orzelska-Górka J, Mikulska J, Wiszniewska A, Biała G (2022) New atypical antipsychotics in the treatment of schizophrenia and depression. Int J Mol Sci. https://doi.org/10.3390/ijms231810624

Article  PubMed  PubMed Central  Google Scholar 

Keshavan MS, Collin G, Guimond S, Kelly S, Prasad KM, Lizano P (2020) Neuroimaging in Schizophrenia. Neuroimag Clin North America 30(1):73–83. https://doi.org/10.1016/j.nic.2019.09.007

Article  Google Scholar 

Liang Y, Wu M, Zou Y, Wan X, Liu Y, Liu X (2023) Prevalence of suicide ideation, self-harm, and suicide among Chinese patients with schizophrenia: a systematic review and meta-analysis. Front Public Health. https://doi.org/10.3389/fpubh.2023.1097098

Article  PubMed  PubMed Central  Google Scholar 

Álvarez A et al (2022) A systematic review and meta-analysis of suicidality in psychotic disorders: stratified analyses by psychotic subtypes, clinical setting and geographical region. Neurosci Biobehav Rev. https://doi.org/10.1016/j.neubiorev.2022.104964

Article  PubMed  Google Scholar 

Correll CU, Solmi M, Croatto G, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J (2022) Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry 21(2):248–71

Article  PubMed  PubMed Central  Google Scholar 

Khandaker GM, Cousins L, Deakin J, Lennox BR, Yolken R, Jones PB (2015) Inflammation and immunity in schizophrenia: Implications for pathophysiology and treatment. Lancet Psychiatry 2(3):258–270. https://doi.org/10.1016/S2215-0366(14)00122-9

Article  PubMed  PubMed Central  Google Scholar 

Roy A, Segal NL, Centerwall BS, Dennis Robinette C. Hospital, ‘Suicide in Twins Subsequent to collection of these 11 twin pairs, previously unpublished data about suicide in twins surfaced (collected by’. [Online]. Available: http://archpsyc.jamanetwork.com/

Roy A, Segal NL (2001) ‘Suicidal behavior in twins: a replication’. [Online]. Available: https://www.sciencedirect.com/journal/journal-of-affective-disorders

Li QS et al (2023) Genome-wide association study meta-analysis of suicide death and suicidal behavior. Mol Psychiatry 28(2):891–900. https://doi.org/10.1038/s41380-022-01828-9

Article  CAS  PubMed  Google Scholar 

Cardno AG, Gottesman II (2000) Twin studies of schizophrenia: from bow-and-arrow concordances to star wars mx and functional genomics. Am J Med Genet. https://doi.org/10.1002/(SICI)1096-8628(200021)

Article  PubMed  Google Scholar 

Legge SE, Santoro ML, Periyasamy S, Okewole A, Arsalan A, Kowalec K (2021) Genetic architecture of schizophrenia: a review of major advancements. Psychol Med 51(13):2168–2177. https://doi.org/10.1017/S0033291720005334

Article  PubMed  Google Scholar 

Gawde U et al (2022) ‘Multimorbidity landscape of schizophrenia: Insights from meta-analysis of genome wide association studies. Schizophrenia Res 243:214–216. https://doi.org/10.1016/j.schres.2022.03.013

Article  CAS  Google Scholar 

Liu J et al (2021) Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia. BMC Med. https://doi.org/10.1186/s12916-021-02039-9

Article  PubMed  PubMed Central  Google Scholar 

Harmer B, Lee S, Vi Duong TH, Saadabadi A. ‘Suicidal Ideation continuing education activity. [Online]. Available: https://www-ncbi-nlm-nih-gov.auh.aub.aau.dk/books/NBK565877/

Purcell S et al (2007) PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81(3):559–575. https://doi.org/10.1086/519795

Article  CAS  PubMed  PubMed Central  Google Scholar 

Team RC (2020) A language and environment for statistical computing

Alexa A, Rahnenführer J (2023) Gene set enrichment analysis with topGO. [Online]. Available: https://www.mpi-inf.mpg.de/%e2%88%bcalexa

‘Package “Reactome PA”’, https://doi.org/10.18129/B9.bioc.ReactomePA

Gillespie M et al (2022) The reactome pathway knowledgebase 2022. Nucleic Acids Res 50(D1):D687–D692. https://doi.org/10.1093/nar/gkab1028

Article  CAS  PubMed  Google Scholar 

Addington J, Shah H, Liu L, Addington D (2014) Reliability and validity of the Calgary Depression Scale for Schizophrenia (CDSS) in youth at clinical high risk for psychosis. Schizophr Res 153(1–3):64–67. https://doi.org/10.1016/j.schres.2013.12.014

Article  PubMed  PubMed Central  Google Scholar 

Berman AL, Silverman MM (2017) How to ask about suicide? A question in need of an empirical answer. Crisis 38(4):213–216. https://doi.org/10.1027/0227-5910/a000501

Article  PubMed  Google Scholar 

Glenn CR, Kleiman EM, Cha CB, Deming CA, Franklin JC, Nock MK (2018) Understanding suicide risk within the research domain criteria (RDoC) framework: a meta-analytic review. Depress Anxiety 35(1):65–88. https://doi.org/10.1002/da.22686

Article  PubMed  Google Scholar 

American Psychiatric Association (2015) The American Psychiatric Association practice guidelines for the psychiatric evaluation of adults. Am Psychiatric Assoc. https://doi.org/10.1176/appi.books.9780890426760

Article  Google Scholar 

Berman AL (2018) Risk factors proximate to suicide and suicide risk assessment in the context of denied suicide ideation. Suicide Life Threat Behav 48(3):340–352. https://doi.org/10.1111/sltb.12351

Article  PubMed 

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