Loscalzo J. Venous thrombosis in the nephrotic syndrome. N Engl J Med. 2013;368(10):956–8.

Article  CAS  PubMed  Google Scholar 

Kelddal S, Nykjær KM, Gregersen JW, Birn H. Prophylactic anticoagulation in nephrotic syndrome prevents thromboembolic complications. BMC Nephrol. 2019;20(1):139.

Article  PubMed  PubMed Central  Google Scholar 

Gordon-Cappitelli J, Choi MJ. Prophylactic anticoagulation in adult patients with nephrotic syndrome. Clin J Am Soc Nephrol. 2020;15(1):123–5.

Article  PubMed  Google Scholar 

Kerlin BA, Ayoob R, Smoyer WE. Epidemiology and pathophysiology of nephrotic syndrome-associated thromboembolic disease. Clin J Am Soc Nephrol. 2012;7(3):513–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barbano B, Gigante A, Amoroso A, Cianci R. Thrombosis in nephrotic syndrome. Semin Thromb Hemost. 2013;39(5):469–76.

Article  CAS  PubMed  Google Scholar 

Eneman B, Levtchenko E, van den Heuvel B, Van Geet C, Freson K. Platelet abnormalities in nephrotic syndrome. Pediatr Nephrol. 2016;31(8):1267–79.

Article  PubMed  Google Scholar 

Allen N, Barrett TJ, Guo Y, Nardi M, Ramkhelawon B, Rockman CB, et al. Circulating monocyte-platelet aggregates are a robust marker of platelet activity in cardiovascular disease. Atherosclerosis. 2019;282:11–8.

Article  CAS  PubMed  Google Scholar 

Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation. 2001;104(13):1533–7.

Article  CAS  PubMed  Google Scholar 

Freedman JE, Loscalzo J. Platelet-monocyte aggregates: bridging thrombosis and inflammation. Circulation. 2002;105(18):2130–2.

Article  PubMed  Google Scholar 

Seizer P, Gawaz M, May AE. Platelet-monocyte interactions–a dangerous liaison linking thrombosis, inflammation and atherosclerosis. Curr Med Chem. 2008;15:1976–80.

Article  CAS  PubMed  Google Scholar 

Rolling CC, Barrett TJ, Berger JS. Platelet-monocyte aggregates: molecular mediators of thromboinflammation. Front Cardiovasc Med. 2023;10:960398.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kapellos TS, Bonaguro L, Gemünd I, Reusch N, Saglam A, Hinkley ER, et al. Human monocyte subsets and phenotypes in Major Chronic Inflammatory diseases. Front Immunol. 2019;10:2035.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Patkó Z, Császár A, Acsády G, Ory I, Takács E, Fűrész J. Elevation of monocyte-platelet aggregates is an early marker of type 2 diabetes. Interv Med Appl Sci. 2012;4(4):181–5.

PubMed  PubMed Central  Google Scholar 

Zeng S, Zhou X, Ge L, Ji WJ, Shi R, Lu RY, et al. Monocyte subsets and monocyte-platelet aggregates in patients with unstable angina. J Thromb Thrombolysis. 2014;38(4):439–46.

Article  CAS  PubMed  Google Scholar 

Loguinova M, Pinegina N, Kogan V, Vagida M, Arakelyan A, Shpektor A, et al. Monocytes of different subsets in complexes with platelets in patients with myocardial infarction. Thromb Haemost. 2018;118(11):1969–81.

Article  PubMed  PubMed Central  Google Scholar 

Kossmann H, Rischpler C, Hanus F, Nekolla SG, Kunze KP, Götze K, et al. Monocyte-platelet aggregates affect local inflammation in patients with acute myocardial infarction. Int J Cardiol. 2019;287:7–12.

Article  PubMed  Google Scholar 

Lukasik M, Dworacki G, Kufel-Grabowska J, Watala C, Kozubski W. Upregulation of CD40 ligand and enhanced monocyte-platelet aggregate formation are associated with worse clinical outcome after ischaemic stroke. Thromb Haemost. 2012;107(2):346–55.

Article  CAS  PubMed  Google Scholar 

Le Joncour A, Biard L, Vautier M, Bugaut H, Mekinian A, Maalouf G, et al. Neutrophil-platelet and monocyte-platelet aggregates in COVID-19 patients. Thromb Haemost. 2020;120(12):1733–5.

Article  PubMed  PubMed Central  Google Scholar 

Kidney Disease. Improving global outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2013;3:5–14.

Google Scholar 

Schrottmaier WC, Kral JB, Badrnya S, Assinger A. Aspirin and P2Y12 inhibitors in platelet-mediated activation of neutrophils and monocytes. Thromb Haemost. 2015;114(3):478–89.

Article  PubMed  Google Scholar 

Patko Z, Csaszar A, Acsady G, Peter K, Schwarz M. Roles of Mac-1 and glycoprotein IIb/IIIa integrins in leukocyte-platelet aggregate formation: stabilization by Mac-1 and inhibition by GpIIb/IIIa blockers. Platelets. 2012;23(5):368–75.

Article  CAS  PubMed  Google Scholar 

Lisman T. Platelet-neutrophil interactions as drivers of inflammatory and thrombotic disease. Cell Tissue Res. 2018;371(3):567–76.

Article  CAS  PubMed  Google Scholar 

Krychtiuk KA, Kastl SP, Hofbauer SL, Wonnerth A, Goliasch G, Ozsvar-Kozma M, et al. Monocyte subset distribution in patients with stable atherosclerosis and elevated levels of lipoprotein(a). J Clin Lipidol. 2015;9(4):533–41.

Article  PubMed  PubMed Central  Google Scholar 

Hottz ED, Medeiros-de-Moraes IM, Vieira-de-Abreu A, de Assis EF, Vals-de-Souza R, Castro-Faria-Neto HC, et al. Platelet activation and apoptosis modulate monocyte inflammatory responses in dengue. J Immunol. 2014;193(4):1864–72.

Article  CAS  PubMed  Google Scholar 

Dann R, Hadi T, Montenont E, Boytard L, Alebrahim D, Feinstein J, et al. Platelet-derived MRP-14 induces monocyte activation in patients with symptomatic peripheral artery disease. J Am Coll Cardiol. 2018;71(1):53–65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mandel J, Casari M, Stepanyan M, Martyanov A, Deppermann C. Beyond hemostasis: platelet innate Immune interactions and thromboinflammation. Int J Mol Sci. 2022;23(7):3868.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hottz ED, Martins-Gonçalves R, Palhinha L, Azevedo-Quintanilha IG, de Campos MM, Sacramento CQ, et al. Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19. Blood Adv. 2022;6(17):5085–99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rolling CC, Sowa MA, Wang TT, Cornwell M, Myndzar K, Schwartz T, et al. P2Y12 inhibition suppresses proinflammatory platelet-monocyte interactions. Thromb Haemost. 2023;123(2):231–44.

Article  PubMed  PubMed Central  Google Scholar 

Gyamlani G, Molnar MZ, Lu JL, Sumida K, Kalantar-Zadeh K, Kovesdy CP. Association of serum albumin level and venous thromboembolic events in a large cohort of patients with nephrotic syndrome. Nephrol Dial Transpl. 2017;32(1):157–64.

Article  CAS  Google Scholar 

Hassouna HI. Thrombophilia and hypercoagulability. Med Princ Pract. 2009;18(6):429–40.

Article  PubMed  Google Scholar 

Agrawal S, Zaritsky JJ, Fornoni A, Smoyer WE. Dyslipidaemia in nephrotic syndrome: mechanisms and treatment. Nat Rev Nephrol. 2018;14(1):57–70.

Article  CAS  PubMed