The cryo-EM data were collected at the Advanced Center for Electron Microscopy, Shanghai Institute of Materia Medica. The authors thank the staff at the Advanced Center for Electron Microscopy for their technical support. This work was partially supported by the National Natural Science Foundation of China (82373881 to J.D., 32130022 and 82121005 to H.E.X.); Young Elite Scientists Sponsorship Program by CAST (2022QNRC001 to J.D.); Shanghai Sailing Program (23YF1456800 to J.D.); the Youth Innovation Promotion Association of Chinese Academy of Sciences (to J.D.); Ministry of Science and Technology (China) grants (2018YFA0507002 to H.E.X.); Shanghai Municipal Science and Technology Major Project (2019SHZDZX02 to H.E.X.); Shanghai Municipal Science and Technology Major Project (H.E.X.); CAS Strategic Priority Research Program (XDB37030103 to H.E.X.); Shanghai Pujiang Program (23PJ1415200 to Y.L.).