Shah NH, Adams D. Episodic aphasia associated with cortical spreading depression after subdural hemorrhage evacuation. Neurohospitalist. 2016;6(1):1–4.

Article  Google Scholar 

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1): 1–211.

Zhao J, Blaeser AS, Levy D. Astrocytes mediate migraine-related intracranial meningeal mechanical hypersensitivity. Pain. 2021;162(9):2386–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leão AA. Spreading depression. Funct Neurol. 1986;1(4):363–6.

PubMed  Google Scholar 

Close LN, et al. Cortical spreading depression as a site of origin for migraine: role of CGRP. Cephalalgia. 2019;39(3):428–34.

Article  PubMed  Google Scholar 

Charles A, Brennan K. Cortical spreading depression-new insights and persistent questions. Cephalalgia. 2009;29(10):1115–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Borkum JM. Brain energy deficit as a source of oxidative stress in migraine: a molecular basis for migraine susceptibility. Neurochem Res. 2021;46(8):1913–32.

Article  CAS  PubMed  Google Scholar 

Feuerstein D, et al. Regulation of cerebral metabolism during cortical spreading depression. J Cereb Blood Flow Metab. 2016;36(11):1965–77.

Article  CAS  PubMed  Google Scholar 

Xu J, et al. Requirement of glycogenolysis for uptake of increased extracellular K+ in astrocytes: potential implications for K+ homeostasis and glycogen usage in brain. Neurochem Res. 2013;38(3):472–85.

Article  CAS  PubMed  Google Scholar 

Sugimoto H, et al. Astrocytes in Atp1a2-deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression. FEBS Open Bio. 2020;10(6):1031–43.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Unekawa M, et al. Enhanced susceptibility to cortical spreading depression in two types of Na(+), K(+)-ATPase α2 subunit-deficient mice as a model of familial hemiplegic migraine 2. Cephalalgia. 2018;38(9):1515–24.

Article  PubMed  Google Scholar 

Auffenberg E, et al. Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. J Clin Investig. 2021;131(21): e142202.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kros L, Lykke-Hartmann K, Khodakhah K. Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2. Sci Rep. 2018;8(1): 16959.

Article  PubMed  PubMed Central  Google Scholar 

Capuani C, et al. Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2. EMBO Mol Med. 2016;8(8):967–86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Parker PD, et al. Non-canonical glutamate signaling in a genetic model of migraine with aura. Neuron. 2021;109(4):611-628.e8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou X, et al. Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine. J Neurochem. 2020;155(4):370–89.

Article  CAS  PubMed  Google Scholar 

Zhao J, Levy D. Dissociation between CSD-evoked metabolic perturbations and meningeal afferent activation and sensitization: implications for mechanisms of migraine headache onset. J Neurosci. 2018;38(22):5053–66.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Torrente D, et al. Cortical spreading depression in traumatic brain injuries: is there a role for astrocytes? Neurosci Lett. 2014;565:2–6.

Article  CAS  PubMed  Google Scholar 

Ayata C, Lauritzen M. Spreading depression, spreading depolarizations, and the cerebral vasculature. Physiol Rev. 2015;95(3):953–93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Iadecola C. The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease. Neuron. 2017;96(1):17–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tóth R, et al. Astrocyte Ca(2+) waves and subsequent non-synchronized Ca(2+) oscillations coincide with arteriole diameter changes in response to spreading depolarization. Int J Mol Sci. 2021;22(7):3442.

Article  PubMed  PubMed Central  Google Scholar 

Li C, et al. Regional temperature and quantitative cerebral blood flow responses to cortical spreading depolarization in the rat. J Cereb Blood Flow Metab. 2017;37(5):1634–40.

Article  PubMed  Google Scholar 

Giovannoni F, Quintana FJ. The role of astrocytes in CNS inflammation. Trends Immunol. 2020;41(9):805–19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Verkhratsky A, Nedergaard M. Physiology of astroglia. Physiol Rev. 2018;98(1):239–389.

Article  CAS  PubMed  Google Scholar 

Li J, et al. Energy metabolic disorder of astrocytes may be an inducer of migraine attack. Brain Sci. 2022;12(7):844.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Linnerbauer M, Rothhammer V. Protective functions of reactive astrocytes following central nervous system insult. Front Immunol. 2020;11: 573256.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou B, Zuo YX, Jiang RT. Astrocyte morphology: diversity, plasticity, and role in neurological diseases. CNS Neurosci Ther. 2019;25(6):665–73.

Article  PubMed  PubMed Central  Google Scholar 

Vasile F, Dossi E, Rouach N. Human astrocytes: structure and functions in the healthy brain. Brain Struct Funct. 2017;222(5):2017–29.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, et al. Protection against acute cerebral ischemia/reperfusion injury by Leonuri Herba Total Alkali via modulation of BDNF-TrKB-PI3K/Akt signaling pathway in rats. Biomed Pharmacother. 2021;133: 111021.

Article  CAS  PubMed  Google Scholar 

Borkum JM. Migraine triggers and oxidative stress: a narrative review and synthesis. Headache. 2016;56(1):12–35.

Article  PubMed  Google Scholar 

Carter SF, et al. Astrocyte biomarkers in Alzheimer’s disease. Trends Mol Med. 2019;25(2):77–95.

Article  CAS  PubMed  Google Scholar 

Rovegno M, Sáez JC. Role of astrocyte connexin hemichannels in cortical spreading depression. Biochim Biophys Acta Biomembr. 2018;1860(1):216–23.

Article  CAS