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A Novel Combination Strategy of Ultrasound-Guided Percutaneous Radiofrequency Ablation and Corticosteroid Injection for Treating Recalcitrant Plantar Fasciitis: A Retrospective Comparison Study
A Novel Combination Strategy of Ultrasound-Guided Percutaneous Radiofrequency Ablation and Corticosteroid Injection for Treating Recalcitrant Plantar Fasciitis: A Retrospective Comparison Study
The best treatment yielding clinical benefits was still equivocal and controversial for the treatment of recalcitrant plan...
Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy
Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy
Drawbacks of fixed-output spinal cord stimulation (SCS) screening trials may lead to compromised trial outcomes and poor p...
A Retrospective Analysis of Disease Epidemiology, Comorbidity Burden, Treatment Patterns, and Healthcare Resource Utilization of Migraine in the United Arab Emirates
A Retrospective Analysis of Disease Epidemiology, Comorbidity Burden, Treatment Patterns, and Healthcare Resource Utilization of Migraine in the United Arab Emirates
Migraine is a recurrent, disabling neurological disorder with a substantial global disease burden. However, limited real-w...
Transforaminal Steroid Injection After Dorsal Root Ganglion Pulsed Radiofrequency (DRG-PRF): Impact on Pain Intensity and Disability
Transforaminal Steroid Injection After Dorsal Root Ganglion Pulsed Radiofrequency (DRG-PRF): Impact on Pain Intensity and Disability
Dorsal root ganglion pulsed radiofrequency (DRG-PRF) is frequently used for the treatment of chronic lumbar radicular pain...
Cerebral Artery Vasoconstriction After Galcanezumab Loading Dose for Migraine Prevention: A Case Report
Cerebral Artery Vasoconstriction After Galcanezumab Loading Dose for Migraine Prevention: A Case Report
Anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies that target CGRP ligands or receptors, may cause a very ...
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Current guidelines for pain treatment recommend a personalized, multimodal and interdisciplinary approach as well as the u...
Understanding Headaches Attributed to Cranial and/or Cervical Vascular Disorders: Insights and Challenges for Neurologists
Understanding Headaches Attributed to Cranial and/or Cervical Vascular Disorders: Insights and Challenges for Neurologists
In recent decades, cranial and cervical vascular disorders have become major global health concerns, significantly impacti...
Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy
Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy
Ciprofol is a novel propofol analogue with a characteristic of hemodynamic stability. At present, there is a lack of resea...
Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
Critically ill patients often endure pain, a distressing experience that can trigger diverse pathophysiological consequenc...
Unaltered Responses of Distal Motor Neurons to Non-Targeted Thoracic Spinal Cord Stimulation in Chronic Pain Patients
Unaltered Responses of Distal Motor Neurons to Non-Targeted Thoracic Spinal Cord Stimulation in Chronic Pain Patients
Spinal cord stimulation (SCS) represents an established interventional pain therapeutic; however, the SCS effects of SCS w...
Real-World Experience of Erenumab in Patients with Migraine in Germany: The SPECTRE Study
Real-World Experience of Erenumab in Patients with Migraine in Germany: The SPECTRE Study
To provide real-world insights into migraine patient population in Germany treated with erenumab, focusing on the prescrip...
Abdominal Pain in Inflammatory Bowel Disease-Epidemiology, Pathophysiology, and Management: A Narrative Review
Abdominal Pain in Inflammatory Bowel Disease-Epidemiology, Pathophysiology, and Management: A Narrative Review
Abdominal pain is a major symptom of inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative coli...
Pain-Insomnia-Depression Syndrome: Triangular Relationships, Pathobiological Correlations, Current Treatment Modalities, and Future Direction
Pain-Insomnia-Depression Syndrome: Triangular Relationships, Pathobiological Correlations, Current Treatment Modalities, and Future Direction
Pain-insomnia-depression syndrome (PIDS) is a complex triad of chronic pain, insomnia, and depression that has profound ef...
Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks
Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks
Around 91% of migraine patients use over-the-counter medicines to treat attacks, often without further treatment or medica...
Correlations of The Central Sensitization Inventory, conditioned pain modulation, cognitions and psychological factors in individuals with chronic neck pain: A cross-sectional study
Correlations of The Central Sensitization Inventory, conditioned pain modulation, cognitions and psychological factors in individuals with chronic neck pain: A cross-sectional study
Chronic neck pain (CNP) is a global public health problem, with high prevalence and absenteeism rates. Central sensitizati...
Efficacy and Adverse Effects of IV Morphine for Burn Pain Management in the Emergency Department: An Observational Study
Efficacy and Adverse Effects of IV Morphine for Burn Pain Management in the Emergency Department: An Observational Study
The management of pain following a burn is extremely complex because of the multifactorial nature of burn pain (nociceptiv...
Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study
Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study
Up to 50% of diabetic patients with neuropathy suffer from chronic pain, namely painful diabetic neuropathy (PDN), an unme...
Development of a Prediction Model and Corresponding Scoring Table for Postherpetic Neuralgia Using Six Machine Learning Algorithms: A Retrospective Study
Development of a Prediction Model and Corresponding Scoring Table for Postherpetic Neuralgia Using Six Machine Learning Algorithms: A Retrospective Study
Postherpetic neuralgia (PHN), a complication of herpes zoster, significantly impacts the quality of life of affected patie...
Analgesic Effectiveness of Truncal Plane Blocks in Patients Undergoing the Nuss Procedure: A Randomized Controlled Trial
Analgesic Effectiveness of Truncal Plane Blocks in Patients Undergoing the Nuss Procedure: A Randomized Controlled Trial
Most patients undergoing the Nuss procedure reported moderate to severe pain after surgery. This study aimed to investigat...
The Use of High-Dose Intravenous l-Ascorbate in Pain Therapy: Current Evidence from the Literature
The Use of High-Dose Intravenous l-Ascorbate in Pain Therapy: Current Evidence from the Literature
Pain is the most common reason for seeking medical treatment. Despite extensive research efforts and effective analgesics ...
Transcutaneous Electrical Acupoint Stimulation Combined with Moderate Sedation of Remimazolam Tosilate in Gastrointestinal Endoscopy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Transcutaneous Electrical Acupoint Stimulation Combined with Moderate Sedation of Remimazolam Tosilate in Gastrointestinal Endoscopy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Further clinical validation is required to determine whether transcutaneous electrical acupoint stimulation (TEAS) can rep...
The Role of Astrocytes in Migraine with Cortical Spreading Depression: Protagonists or Bystanders? A Narrative Review
The Role of Astrocytes in Migraine with Cortical Spreading Depression: Protagonists or Bystanders? A Narrative Review
Cortical spreading depression (CSD) is a slow wave of cortical depolarization closely associated with migraines with an au...
Tension-Type Headache Management: A Systematic Review and Network Meta-analysis of Complementary and Alternative Medicine
Tension-Type Headache Management: A Systematic Review and Network Meta-analysis of Complementary and Alternative Medicine
Tension-type headache (TTH) is common but challenging to manage due to limited effectiveness of conventional treatments. T...
Percutaneous Foraminal Neuroplasty Using Reference Spinal Needles: Technical Description
Percutaneous Foraminal Neuroplasty Using Reference Spinal Needles: Technical Description
Lumbar foraminal stenosis is a common cause of chronic lower back pain and radiculopathy often treated by epidural steroid...
H-Wave® Device Stimulation for Chronic Neck Pain: A Patient-Reported Outcome Measures (PROMs) Study
H-Wave® Device Stimulation for Chronic Neck Pain: A Patient-Reported Outcome Measures (PROMs) Study
Chronic neck pain (cNP) is one of the leading causes of disability worldwide, often being refractory to conventional forms...
Cortical Mechanisms Underlying Effects of Repetitive Peripheral Magnetic Stimulation on Dynamic and Static Postural Control in Patients with Chronic Non-Specific Low Back Pain: A Double-Blind Randomized Clinical Trial
Cortical Mechanisms Underlying Effects of Repetitive Peripheral Magnetic Stimulation on Dynamic and Static Postural Control in Patients with Chronic Non-Specific Low Back Pain: A Double-Blind Randomized Clinical Trial
Patients with chronic non-specific low back pain (CNLBP) often experience impaired postural control, contributing to pain ...
Dexketoprofen Trometamol and Tramadol Hydrochloride Fixed-Dose Combination in Moderate to Severe Acute Low Back Pain: A Phase IV, Randomized, Parallel Group, Placebo, Active-Controlled Study (DANTE)
Dexketoprofen Trometamol and Tramadol Hydrochloride Fixed-Dose Combination in Moderate to Severe Acute Low Back Pain: A Phase IV, Randomized, Parallel Group, Placebo, Active-Controlled Study (DANTE)
Dexketoprofen/tramadol 25/75 mg (DKP/TRAM) is a fixed-dose combination of a cyclooxygenase inhibitor and opioid receptor a...
Innovative Applications of Telemedicine and Other Digital Health Solutions in Pain Management: A Literature Review
Innovative Applications of Telemedicine and Other Digital Health Solutions in Pain Management: A Literature Review
Since the COVID-19 pandemic, healthcare systems are facing extraordinary challenges. Our approaches to medicine have chang...
Postoperative Dexmedetomidine Infusion and Chronic Postsurgical Pain in Thoracoscopic Pulmonary Nodule Surgery: A Retrospective Study with Propensity-Score-Matched Analysis
Postoperative Dexmedetomidine Infusion and Chronic Postsurgical Pain in Thoracoscopic Pulmonary Nodule Surgery: A Retrospective Study with Propensity-Score-Matched Analysis
Patients frequently suffer from debilitating chronic postsurgical pain (CPSP) subsequent to thoracoscopic surgery. The imp...
Gut Microbiota Modulation and Its Implications on Neuropathic Pain: A Comprehensive Literature Review
Gut Microbiota Modulation and Its Implications on Neuropathic Pain: A Comprehensive Literature Review
Neuropathic pain (NP) is a chronic pain disorder arising from somatosensory nervous system impairment. Extensive evidence ...
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