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Establishment of a multi-parameter flow cytometry method to identify and characterize neutrophil extracellular traps
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A synergy of CD133 overexpression and TGF-β supplementation in tumorigenesis of ovarian cancer cell lines in a three-dimensional sphere forming model
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Divergent metabolic rewiring shapes altered innate immunity
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Exploring novel strategies of oncolytic viruses and gut microbiota to enhance CAR-T cell therapy for colorectal cancer
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EGCG remodels the TGF-β cervical cancer micro-environment towards immune responsiveness
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Exosomes from hypoxic pretreated BMSCs attenuate primary Sjögren's syndrome-induced skin injury via PPARγ-mediated M2-like macrophage activation
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Follicular helper T cells and fibrotic diseases
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Cgas deficiency promotes tumor growth by supporting B cell persistence and angiogenesis
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Macrophages: Traffic centers in the tumor immune microenvironment
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Establishment of a mouse hepatocellular carcinoma tumoroid panel recapitulating inter- and intra- heterogeneity for disease modelling and combinatorial drug discovery
Establishment of a mouse hepatocellular carcinoma tumoroid panel recapitulating inter- and intra- heterogeneity for disease modelling and combinatorial drug discovery
Hepatocellular carcinoma (HCC) is characterised by a remarkable molecular heterogeneity and resistance to current therapie...
IGFBP2 alteration contributes to prostate cancer progression by modulating prostate stroma activation
IGFBP2 alteration contributes to prostate cancer progression by modulating prostate stroma activation
Insulin-like growth factor (IGF) binding protein-2 (IGFBP2) is a secretory protein that modulate the activity of IGFs. It ...
The primary cilium as a multifunctional organelle: emerging roles and unanswered questions
The primary cilium as a multifunctional organelle: emerging roles and unanswered questions
The primary cilium, a solitary membrane-bound, microtubule-based cellular organelle, has been considered an evolutionary r...
Tubacin alleviate the reproductive toxicity of deoxynivalenol in mouse oocytes and zygotes via strengthening microtubule stability
Tubacin alleviate the reproductive toxicity of deoxynivalenol in mouse oocytes and zygotes via strengthening microtubule stability
Deoxynivalenol (DON) is one of the most common food contaminants, widely present in grain products. Studies using murine a...
Endothelial cell-derived apoptotic bodies modulate innate and adaptive immune responses during inflammation
Endothelial cell-derived apoptotic bodies modulate innate and adaptive immune responses during inflammation
Endothelial cells (ECs) act as gatekeepers and signalling hubs that coordinate communication between blood vessels and sur...
Expression and Purification of an Archaeal Cysteine-less LOV Domain
Expression and Purification of an Archaeal Cysteine-less LOV Domain
LOV (Light Oxygen Voltage) domains are ubiquitous blue light sensors widespread in all three domains of life. They mediate...
Testing SAXS Applicability for Detection of Illumination-Driven Structural Changes in the Purple Membranes from
Testing SAXS Applicability for Detection of Illumination-Driven Structural Changes in the Purple Membranes from
Rhodopsins are photosensitive transmembrane proteins found in bacteria, archaea, and eukaryotes. Upon photon absorption, t...
Identification of Amino Acid Residues Involved in the pH Sensitivity of Receptor Tyrosine Kinase IRR
Identification of Amino Acid Residues Involved in the pH Sensitivity of Receptor Tyrosine Kinase IRR
IRR is a member of the insulin receptor (IR) family that has no known endogenous peptide agonists but can be activated by ...
The International Scientific Conference “Biomembranes 2024”
The International Scientific Conference “Biomembranes 2024”
The International Scientific Conference “Biomembranes 2024” was held from October 7 t...
Capabilities of SEC-SAXS Method in Research of Polydisperse Systems: The Case of Apoferritin
Capabilities of SEC-SAXS Method in Research of Polydisperse Systems: The Case of Apoferritin
Here we explore capabilities of size exclusion chromatography small-angle X-ray scattering method in case of horse spleen ...
Behavioral Correlates of Migraine, Oxidative Stress, and CGRP Levels in the Experimental Model of Chronic Migraine with Aura in Rats
Behavioral Correlates of Migraine, Oxidative Stress, and CGRP Levels in the Experimental Model of Chronic Migraine with Aura in Rats
Migraine is a common chronic neurovascular disease accompanied by unilateral headache, photophobia, allodynia, and autonom...
Searching for the Role of Mechanosensitive PIEZO1 Channel in Cell Motility and Migration of Human Aggressive Melanoma SK-MEL-2 Cells
Searching for the Role of Mechanosensitive PIEZO1 Channel in Cell Motility and Migration of Human Aggressive Melanoma SK-MEL-2 Cells
Melanoma is one of the most common cancers in the world, especially in young adults. Due to the emergence of the resistanc...
Expression and Stabilization of Recombinant Human C3aR Receptor
Expression and Stabilization of Recombinant Human C3aR Receptor
The complement system is an important part of the immune system that controls the body’s defense against pathogens. ...
Investigating Dual Modulatory Role of Mallotoxin on KCNQ1–KCNE Complexes Using Molecular Modeling
Investigating Dual Modulatory Role of Mallotoxin on KCNQ1–KCNE Complexes Using Molecular Modeling
The voltage-gated potassium ion channel KCNQ1 has physiological importance in modulation of electrical excitability in car...
Effect of Ionic Strength on Chloroplast ATP Synthase
Effect of Ionic Strength on Chloroplast ATP Synthase
ATP synthase is a membrane protein complex that plays a crucial role in cellular bioenergetics. The formation of I-shaped ...
ROS Generation in Mitochondria and Cytosol during Optogenetic Cytosol Alkalization in Human Cells
ROS Generation in Mitochondria and Cytosol during Optogenetic Cytosol Alkalization in Human Cells
Optogenetics allows a precise control of a vast variety of cellular processes in excitable and non-excitable cells, in par...
Synthesis of New Uracil Derivatives with Antiviral and Anticancer Potential
Synthesis of New Uracil Derivatives with Antiviral and Anticancer Potential
The need for new effective compounds that can serve as prototype drugs for the treatment of viral infections and various t...
Multiplexed Detection of Epitope Specific T-Cell Responses Using CD20 Trogocytosis
Multiplexed Detection of Epitope Specific T-Cell Responses Using CD20 Trogocytosis
Discovery of antigen epitopes and cognate T-cell receptors (TCRs) is one of the central challenges in the development of t...
Modeling of Protein–Protein Interaction within Landau–Ginzburg–Wilson Approach Using α-Synuclein As an Example
Modeling of Protein–Protein Interaction within Landau–Ginzburg–Wilson Approach Using α-Synuclein As an Example
Parkinson’s disease is a neurodegenerative disease associated with the destruction of motor neurons. One of the biom...
Investigating the Quantitative PALM Applicability for Studies of Protein Oligomerization in Different Conditions
Investigating the Quantitative PALM Applicability for Studies of Protein Oligomerization in Different Conditions
In this work we aimed to investigate in silico the influence of the common experimental factors on the determination of th...
Patient-Centered Computer Model Comparing Excitation Conduction in Normal and Long-Term Persistence of Atrial Fibrillation
Patient-Centered Computer Model Comparing Excitation Conduction in Normal and Long-Term Persistence of Atrial Fibrillation
Despite significant advances in diagnosis and treatment, atrial fibrillation remains a common cardiac arrhythmia affecting...
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