SCI Abstract

search
+
Expression and Purification of an Archaeal Cysteine-less LOV Domain
Expression and Purification of an Archaeal Cysteine-less LOV Domain
LOV (Light Oxygen Voltage) domains are ubiquitous blue light sensors widespread in all three domains of life. They mediate...
Testing SAXS Applicability for Detection of Illumination-Driven Structural Changes in the Purple Membranes from
Testing SAXS Applicability for Detection of Illumination-Driven Structural Changes in the Purple Membranes from
Rhodopsins are photosensitive transmembrane proteins found in bacteria, archaea, and eukaryotes. Upon photon absorption, t...
Identification of Amino Acid Residues Involved in the pH Sensitivity of Receptor Tyrosine Kinase IRR
Identification of Amino Acid Residues Involved in the pH Sensitivity of Receptor Tyrosine Kinase IRR
IRR is a member of the insulin receptor (IR) family that has no known endogenous peptide agonists but can be activated by ...
The International Scientific Conference “Biomembranes 2024”
The International Scientific Conference “Biomembranes 2024”
The International Scientific Conference “Biomembranes 2024” was held from October 7 t...
Capabilities of SEC-SAXS Method in Research of Polydisperse Systems: The Case of Apoferritin
Capabilities of SEC-SAXS Method in Research of Polydisperse Systems: The Case of Apoferritin
Here we explore capabilities of size exclusion chromatography small-angle X-ray scattering method in case of horse spleen ...
Behavioral Correlates of Migraine, Oxidative Stress, and CGRP Levels in the Experimental Model of Chronic Migraine with Aura in Rats
Behavioral Correlates of Migraine, Oxidative Stress, and CGRP Levels in the Experimental Model of Chronic Migraine with Aura in Rats
Migraine is a common chronic neurovascular disease accompanied by unilateral headache, photophobia, allodynia, and autonom...
Searching for the Role of Mechanosensitive PIEZO1 Channel in Cell Motility and Migration of Human Aggressive Melanoma SK-MEL-2 Cells
Searching for the Role of Mechanosensitive PIEZO1 Channel in Cell Motility and Migration of Human Aggressive Melanoma SK-MEL-2 Cells
Melanoma is one of the most common cancers in the world, especially in young adults. Due to the emergence of the resistanc...
Expression and Stabilization of Recombinant Human C3aR Receptor
Expression and Stabilization of Recombinant Human C3aR Receptor
The complement system is an important part of the immune system that controls the body’s defense against pathogens. ...
Investigating Dual Modulatory Role of Mallotoxin on KCNQ1–KCNE Complexes Using Molecular Modeling
Investigating Dual Modulatory Role of Mallotoxin on KCNQ1–KCNE Complexes Using Molecular Modeling
The voltage-gated potassium ion channel KCNQ1 has physiological importance in modulation of electrical excitability in car...
Effect of Ionic Strength on Chloroplast ATP Synthase
Effect of Ionic Strength on Chloroplast ATP Synthase
ATP synthase is a membrane protein complex that plays a crucial role in cellular bioenergetics. The formation of I-shaped ...
ROS Generation in Mitochondria and Cytosol during Optogenetic Cytosol Alkalization in Human Cells
ROS Generation in Mitochondria and Cytosol during Optogenetic Cytosol Alkalization in Human Cells
Optogenetics allows a precise control of a vast variety of cellular processes in excitable and non-excitable cells, in par...
Synthesis of New Uracil Derivatives with Antiviral and Anticancer Potential
Synthesis of New Uracil Derivatives with Antiviral and Anticancer Potential
The need for new effective compounds that can serve as prototype drugs for the treatment of viral infections and various t...
Multiplexed Detection of Epitope Specific T-Cell Responses Using CD20 Trogocytosis
Multiplexed Detection of Epitope Specific T-Cell Responses Using CD20 Trogocytosis
Discovery of antigen epitopes and cognate T-cell receptors (TCRs) is one of the central challenges in the development of t...
Modeling of Protein–Protein Interaction within Landau–Ginzburg–Wilson Approach Using α-Synuclein As an Example
Modeling of Protein–Protein Interaction within Landau–Ginzburg–Wilson Approach Using α-Synuclein As an Example
Parkinson’s disease is a neurodegenerative disease associated with the destruction of motor neurons. One of the biom...
Investigating the Quantitative PALM Applicability for Studies of Protein Oligomerization in Different Conditions
Investigating the Quantitative PALM Applicability for Studies of Protein Oligomerization in Different Conditions
In this work we aimed to investigate in silico the influence of the common experimental factors on the determination of th...
Patient-Centered Computer Model Comparing Excitation Conduction in Normal and Long-Term Persistence of Atrial Fibrillation
Patient-Centered Computer Model Comparing Excitation Conduction in Normal and Long-Term Persistence of Atrial Fibrillation
Despite significant advances in diagnosis and treatment, atrial fibrillation remains a common cardiac arrhythmia affecting...
Humoral and Cellular Immune Response to the Genetically Detoxified S1 Subunit of Pertussis Toxin in Mice
Humoral and Cellular Immune Response to the Genetically Detoxified S1 Subunit of Pertussis Toxin in Mice
Bordetella pertussis, a gram-negative bacterium responsible for whooping cough, poses severe health risks, especially to y...
Membrane Curvature Controls the Efficiency of Oxidative Phosphorylation System
Membrane Curvature Controls the Efficiency of Oxidative Phosphorylation System
This paper analyzes the structural and functional organization of mitochondria. It is shown that deformation of membrane l...
Registration of NADH Photobleaching for Metabolism–Excitation–Contraction Coupling Studies in Layers of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Registration of NADH Photobleaching for Metabolism–Excitation–Contraction Coupling Studies in Layers of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Investigation of the complex interrelationships of multiple intercellular processes underlying cardiac electrophysiology a...
The Drug-to-Lipid-Ratio Determines Fine Structure of the Liposomal Form of Levofloxacin and Molecular Details of Complex Formation with Mannosylated Chitosan
The Drug-to-Lipid-Ratio Determines Fine Structure of the Liposomal Form of Levofloxacin and Molecular Details of Complex Formation with Mannosylated Chitosan
Here we examined how drug-to-lipid ratio affects the fine structure of anionic liposomes with dipalmitoyl phosphatidylchol...
Organization of the Reserve Pool of Synaptic Vesicles in Nerve Terminals Lacking Protein Liquid Phase Components
Organization of the Reserve Pool of Synaptic Vesicles in Nerve Terminals Lacking Protein Liquid Phase Components
The protein endophilin A, which in the mammalian genome is encoded by three genes, endophilin A1, A2, and A3, regulates th...
Electrophysiology of the Danio rerio Heart
Electrophysiology of the Danio rerio Heart
Tropical teleost fish Danio rerio is increasingly used as a model object for electrophysiological studies of human cardiac...
Influence of Low-Intensive He-Ne Laser Radiation on the Composition and Content of Phospholipids and Sterols in the Callus Tissues of Wheat Тriticum aestivum L.
Influence of Low-Intensive He-Ne Laser Radiation on the Composition and Content of Phospholipids and Sterols in the Callus Tissues of Wheat Тriticum aestivum L.
The effect of He-Ne laser radiation on the composition and content of cell membrane components, namely phospholipids (PL) ...
Physicochemical Features of Thrombin Binding to Platelet Membrane
Physicochemical Features of Thrombin Binding to Platelet Membrane
Thrombin is a key enzyme of the blood coagulation system, which has been actively studied since the beginning of the last ...
Comparative Investigation of the Mechanisms of Calcium Response in Human and Murine Spermatozoa
Comparative Investigation of the Mechanisms of Calcium Response in Human and Murine Spermatozoa
Calcium signaling is a principal method of signal transduction in cells of non-excitable tissues. In both mouse and human ...
The Effect of 20-Hydroxyecdysone on the Functioning of Isolated Mouse Skeletal Muscle Mitochondria
The Effect of 20-Hydroxyecdysone on the Functioning of Isolated Mouse Skeletal Muscle Mitochondria
In this work we have studied the effect of the phytoecdysteroid 20-hydroxyecdysone (20E) on the functioning of mouse skele...
On the Feasibility of Using an Acedan-Based Fluorescent Probe to Monitor Hydrogen Sulfide in Primary Neuronal Cultures
On the Feasibility of Using an Acedan-Based Fluorescent Probe to Monitor Hydrogen Sulfide in Primary Neuronal Cultures
Hydrogen sulfide (H2S), which under physiological conditions exists in cells mainly in the form of the HS– anion, is...
Changes in Histone Code Regulation during the Initiation of Paraptosis-Like Death of HEp-2 Tumor Cells by Oxidized Disulfiram Derivatives
Changes in Histone Code Regulation during the Initiation of Paraptosis-Like Death of HEp-2 Tumor Cells by Oxidized Disulfiram Derivatives
Disulfiram (DSF) and its oxidized derivatives (DSFoxy) are currently being investigated as potential anticancer agents. We...
Structural Studies of Ion Channels: Achievements, Problems, and Perspectives
Structural Studies of Ion Channels: Achievements, Problems, and Perspectives
The superfamily of membrane proteins known as P-loop channels encompasses potassium, sodium, and calcium channels, as well...
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Neurodegenerative diseases, along with cardiovascular and oncological pathologies, are one of the most acute problems of m...
Load More
format_indent_increase