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Redirecting the host immune response to bacterial infection with antibody-recruiting molecules (ARMs)
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Opportunities in exploring chemical biology tools for better strategies against Candida albicans
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Chemical strategies for targeting lipid pathways in bacterial pathogens
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Noncytotoxic catalytic enzyme functional mimics including cyanide poisoning antidotes
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Recent advances in de novo designed metallopeptides as tailored enzyme mimics
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Corrigendum to “Bacterial diterpene synthases: New opportunities for mechanistic enzymology and engineered biosynthesis” [Curr Opin Chem Biol, 16 (2012) 132–141
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Editorial: Unusual enzyme reactions in natural products biosynthesis
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Editorial overview: Transforming intracellular delivery: Innovations in macromolecule transport
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Recent developments in probing the levels and flux of selected organellar cations as well as organellar mechanosensitivity
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Natural and artificial siderophores: Iron-based applications and beyond
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Chemical tools to study and modulate glycan-mediated host-bacteria interactions
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Molecular and biochemical insights from natural and engineered photosynthetic endosymbiotic systems
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Probing ligand-induced local stability shifts: A sensitive approach to identify target proteins and binding sites at the proteomic scale
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TRIMming centrosomal assemblies
TRIMming centrosomal assemblies
Centrosomal protein assemblies can lead to mitotic spindle dysfunction and abnormal cell division. Two studies published i...
UFMylation of ARPC4 facilitates lamellipodia formation and promotes cancer metastasis
UFMylation of ARPC4 facilitates lamellipodia formation and promotes cancer metastasis
Cell migration is a prerequisite for cancer cell invasion and metastasis. The highlighted study shows that UFMylation of A...
TRIP12 structures reveal HECT E3 formation of K29 linkages and branched ubiquitin chains
TRIP12 structures reveal HECT E3 formation of K29 linkages and branched ubiquitin chains
Regulation by ubiquitin depends on E3 ligases forging chains of specific topologies, yet the mechanisms underlying the gen...
Akt-phosphorylated UFL1 UFMylates ArpC4 to promote metastasis
Akt-phosphorylated UFL1 UFMylates ArpC4 to promote metastasis
The role of modification by ubiquitin-fold modifier (‘UFMylation’) in regulating metastasis has remained enigm...
A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA
A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA
The Chd1 chromatin remodeler repositions nucleosomes into evenly spaced arrays, a characteristic of most eukaryotic genes....
Distinct tau filament folds in human MAPT mutants P301L and P301T
Distinct tau filament folds in human MAPT mutants P301L and P301T
Mutations in MAPT, the tau gene, give rise to frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), ...
Structural basis of GluK2 kainate receptor activation by a partial agonist
Structural basis of GluK2 kainate receptor activation by a partial agonist
Kainate receptors (KARs) belong to the family of ionotropic glutamate receptors that regulate neurotransmitter release and...
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
The Unc-51-like kinase protein kinase complex (ULK1C) is the most upstream and central player in the initiation of macroau...
An experimental methodology to measure the effects of intervertebral interventions on the facet biomechanics in situ
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Validity of recurrent neural networks to predict pedal forces and lower limb kinetics in cycling
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In vitro characterisation of the patient-specific haemodynamics of an extracranial peripheral arteriovenous malformation using PIV
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The impact of craft type on operational spine postures in military boat operators
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CFD and PIV analysis of a novel, low shear stress intra-aortic ventricular assist device
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Influence of erythrocyte density on aggregability as a marker of cell age: Dissociation dynamics in extensional flow
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Increased ankle pushoff alters frontal-plane hip and knee mechanics
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Double-leg attack vs. arm-drag: Examining muscle synergy consistency between elite and sub-elite freestyle wrestlers
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Muscle contribution to hip contact force during walking is lower in individuals with femoroacetabular impingement syndrome, compared with controls
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