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Chronic pain and subjective memory problems are dynamic risk factors for functional decline: An ACTIVE longitudinal study
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Neutrophil-to-lymphocyte ratio in aging: Trends and clinical implications
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Mitochondrial dysfunction drives cellular senescence: Molecular mechanisms of inter-organelle communication
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Regulatory mechanisms of transforming growth factor-β in senescence of fibroblast associated with refractory skin diseases
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Senolytic therapy increases replicative capacity by eliminating senescent endothelial cells
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Effects of exercise on gut microbiota in older people with sarcopenia: Study protocol for a randomised controlled trial
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A health promotion behavior intervention for migrant older adults: a randomized controlled trial
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The effect of early time-restricted eating on muscle damage-related biomarkers and anxiety in older men
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D-galactose-induced aging and obese conditions contribute to aging and pathologies in dental pulp of male wistar rats
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Impact of senescent fibroblasts secretome in ovarian cancer dissemination
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Gender disparities in marital status and risk of developing age acceleration: Findings from NHANES 2015–2018
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Letter to the editor: Specialized large language models with explainability for Alzheimer's disease diagnosis
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Differential effects of young and old hematopoietic stem cell niches on bone marrow-derived dendritic cells
Differential effects of young and old hematopoietic stem cell niches on bone marrow-derived dendritic cells
Aging is linked to various dysfunctions of the immune system, including the decline of its primary developmental source: t...
Aging modulates the immunosuppressive, polarizing and metabolic functions of blood-derived myeloid-derived suppressor cells (MDSCs)
Aging modulates the immunosuppressive, polarizing and metabolic functions of blood-derived myeloid-derived suppressor cells (MDSCs)
Immunosenescence describes the gradual remodeling of immune responses, leading to disturbed immune homeostasis and increas...
p38 mitogen-activated protein kinase drives senescence in CD4+ T lymphocytes and increases their pathological potential
p38 mitogen-activated protein kinase drives senescence in CD4+ T lymphocytes and increases their pathological potential
In several diseases, senescent T lymphocytes increase in number and release a senescence-associated secretory phenotype (S...
Ageing and dysregulated lung immune responses in fatal COVID-19
Ageing and dysregulated lung immune responses in fatal COVID-19
Elderly individuals were disproportionally affected during the COVID-19 pandemic, and more than 80% of the global COVID-19...
Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling
Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling
The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plastic...
Impact of lifestyle factors on quantitative motor and cognitive performance: insights from a longitudinal study on healthy ageing
Impact of lifestyle factors on quantitative motor and cognitive performance: insights from a longitudinal study on healthy ageing
The process of ageing is extremely variable in progression and phenotypic features including significant variations in dis...
Synaptic pruning genes networks in Alzheimer’s disease: correlations with neuropathology and cognitive decline
Synaptic pruning genes networks in Alzheimer’s disease: correlations with neuropathology and cognitive decline
Synaptic pruning (SP) is a critical process in brain development and maintenance, essential for refining neural circuits b...
Age-independent anti-angiogenic therapy for choroidal neovascularization by targeting secretogranin III
Age-independent anti-angiogenic therapy for choroidal neovascularization by targeting secretogranin III
Recent studies reported that anti-angiogenic drugs targeting vascular endothelial growth factor (VEGF) alleviate choroidal...
HealthAge: evaluation of intrinsic capacity changes in humans, mice, and killifish to explore the biology of aging
HealthAge: evaluation of intrinsic capacity changes in humans, mice, and killifish to explore the biology of aging
HealthAge was devised by a conglomerate of research groups in Toulouse, France, with the combined goal of narrowing the li...