Vlasov A.V., Osipov S.D., Bondarev N.A., Uversky V.N., et al. 2022. ATP synthase FOF1 structure, function, and structure-based drug design. Cell. Mol. Life Sciences. 79 (3), 179. https://doi.org/10.1007/s00018-022-04153-0
Walker J.E. 2013. The ATP synthase: The understood, the uncertain and the unknown. Biochem. Soc. Transact. 41 (1), 1–16. https://doi.org/10.1042/BST20110773
Kühlbrandt W. 2019. Structure and mechanisms of F‑type ATP synthases. Ann. Rev. Biochem. 88 (1), 515–549, https://doi.org/10.1146/annurev-biochem-013118-110903
Article CAS PubMed Google Scholar
Guo H., Courbon G.M., Bueler S.A., Mai J., Liu J., Rubinstein J.L. 2021. Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature. 589 (7840), 143–147. https://doi.org/10.1038/s41586-020-3004-3
Article CAS PubMed Google Scholar
Hahn A., Vonck J., Mills D.J., Meier T., Kühlbrandt W. 2018. Structure, mechanism, and regulation of the chloroplast ATP synthase. Science. 360 (6389), eaat4318. https://doi.org/10.1126/science.aat4318
Vlasov A.V., Kovalev K.V., Marx S.H., Round E.S., et al. 2019. Unusual features of the c-ring of F1FO ATP synthases. Sci. Rep. 9 (1), 18547. https://doi.org/10.1038/s41598-019-55092-z
Article CAS PubMed PubMed Central Google Scholar
Murphy B.J., Klusch N., Langer J., Mills D.J., Yildiz Ö., Kühlbrandt W. 2019. Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1–Fo coupling. Science. 364 (6446), eaaw9128. https://doi.org/10.1126/science.aaw9128
Mühleip A., McComas S.E., Amunts A. 2019. Structure of a mitochondrial ATP synthase with bound native cardiolipin. Elife. 8, e51179. https://doi.org/10.7554/eLife.51179
Article PubMed PubMed Central Google Scholar
Guo H., Bueler S.A., Rubinstein J.L. 2017. Atomic model for the dimeric FO region of mitochondrial ATP synthase. Science. 358 (6365), 936–940. https://doi.org/10.1126/science.aao4815
Article CAS PubMed PubMed Central Google Scholar
Spikes T., Montgomery M., Walker J.E. 2020. Structure of the dimeric ATP synthase from bovine mitochondria. Proc. Natl. Ac. Sci. USA. 117 (38), 23519–23526. https://doi.org/10.1073/pnas.2013998117
Schulz S., Wilkes M., Mills D.J., Kühlbrandt W., Meier T. 2017. Molecular architecture of the N-type ATP-ase rotor ring from Burkholderia pseudomallei. EMBO Reports. 18 (4), 526–535. https://doi.org/10.15252/embr.201643374
Article CAS PubMed PubMed Central Google Scholar
Osipov S.D., Zinovev E.V., Anuchina A.A., Kuzmin A.S., et al. 2025. High-throughput evaluation of natural diversity of F-type ATP synthase rotor ring stoichiometries. Proteins: Structure, Function, and Bioinformatics. https://doi.org/10.1002/prot.26790
Mühleip A., Kock Flygaard R., Ovciarikova J., Lacombe A., Fernandes P., Sheiner L., Amunts A. 2021. ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nature Com. 12 (1), 120. https://doi.org/10.1038/s41467-020-20381-z
Daum B., Nicastro D., Austin J., McIntosh J.R., Kühlbrandt W. 2010. Arrangement of photosystem II and ATP synthase in chloroplast membranes of spinach and pea. Plant Cell. 22 (4), 1299–1312. https://doi.org/10.1105/TPC.109.071431
Article CAS PubMed PubMed Central Google Scholar
Rexroth S., Zu Tittingdorf J.M.M., Schwaßmann H.J., Krause F., Seelert H., Dencher N.A. 2004. Dimeric H+-ATP synthase in the chloroplast of Chlamydomonas reinhardtii. Biochim. Biophys., Bioenerg. 1658 (3), 202–211. https://doi.org/10.1016/j.bbabio.2004.05.014
Schwaßmann H.J., Rexroth S., Seelert H., Dencher N.A. 2007. Metabolism controls dimerization of the chloroplast FoF1 ATP synthase in Chlamydomonas reinhardtii. FEBS Lett. 581 (7), 1391–1396. https://doi.org/10.1016/j.febslet.2007.02.057
Article CAS PubMed Google Scholar
Seelert H., Dencher N.A. 2011. ATP synthase superassemblies in animals and plants: Two or more are better. Biochim. Biophys. Acta, Bioenerg. 1807 (9), 1185–1197. https://doi.org/10.1016/j.bbabio.2011.05.023
Osipov S.D., Ryzhykau Y.L., Zinovev E.V., Minaeva A.V., et al. 2023. I-shaped dimers of a plant chloroplast FOF1-ATP synthase in response to changes in ionic strength. Intern. J. Mol. Sci. 24 (13), 10720. https://doi.org/10.3390/ijms241310720
Petoukhov M.V., Svergun D.I. 2013. Applications of small-angle X-ray scattering to biomacromolecular solutions. Intern. J. Biochem. Cell Biol. 45 (2), 429–437. https://doi.org/10.1016/j.biocel.2012.10.017
Sobti M., Smits C., Wong A.S., Ishmukhametov R., Stock D., Sandin S., Stewart A.G. 2016. Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states. Elife. 5, e21598. https://doi.org/10.7554/ELIFE.21598
Article PubMed PubMed Central Google Scholar
Guo H., Suzuki T., Rubinstein J.L. 2019. Structure of a bacterial ATP synthase. Elife. 8, e43128. https://doi.org/10.7554/eLife.43128
Article PubMed PubMed Central Google Scholar
Ishmukhametov R.R., Russell A.N., Berry R.M. 2016. A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes. Nature Comm. 7 (1), 13025. https://doi.org/10.1038/ncomms13025
Varco-Merth B., Fromme R., Wang M., Fromme P. 2008. Crystallization of the c14-rotor of the chloroplast ATP synthase reveals that it contains pigments. Biochim. Biophys. Acta, Bioenerg. 1777 (7–8), 605–612. https://doi.org/10.1016/J.BBABIO.2008.05.009
Balakrishna A.M., Seelert H., Marx S.H., Dencher N.A., Grüber G. 2014. Crystallographic structure of the turbine C-ring from spinach chloroplast F-ATP synthase. Biosci. Rep. 34 (2), e00102. https://doi.org/10.1042/BSR20130114
Article CAS PubMed PubMed Central Google Scholar
Magnusson A.O., Szekrenyi A., Joosten H.J., Finnigan J., Charnock S., Fessner W.D. 2019. NanoDSF as screening tool for enzyme libraries and biotechnology development. FEBS J. 286 (1), 184–204. https://doi.org/10.1111/febs.14696
Article CAS PubMed Google Scholar
Wen J., Lord H., Knutson N., Wikström M. 2020. Nano differential scanning fluorimetry for comparability studies of therapeutic proteins. Anal. Biochem. 593, 113581. https://doi.org/10.1016/j.ab.2020.113581
Article CAS PubMed Google Scholar
Vlasov A. 2020. New structural insights in chloroplast F1FO-ATP synthases. Doctoral dissertation, Dissertation, Rheinisch-Westfälische Technische Hochschule. Aachen, 2020.
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