Linders, A.N., I.B. Dias, T.L. Fernández, C.G. Tocchetti, N. Bomer, and P. Van der Meer. 2024. A review of the pathophysiological mechanisms of doxorubicin-induced cardiotoxicity and aging. NPJ Aging 10: 9. https://doi.org/10.1038/s41514-024-00135-7.
Article PubMed PubMed Central Google Scholar
Thorn, C.F., C. Oshiro, S. Marsh, T. Hernandez-Boussard, H. McLeod, T.E. Klein, and R.B. Altman. 2011. Doxorubicin pathways: Pharmacodynamics and adverse effects. Pharmacogenetics and Genomics 21: 440–446. https://doi.org/10.1097/FPC.0b013e32833ffb56.
Article CAS PubMed PubMed Central Google Scholar
Jasim, S.T., H.M. Al-Kuraishy, and A.I. Al-Gareeb. 2019. Gingko Biloba protects cardiomyocytes against acute doxorubicin induced cardiotoxicity by suppressing oxidative stress. JPMA. The Journal of the Pakistan Medical Association 69 (3): S103–S107.
Ikeda, So., S. Matsushima, K. Okabe, M. Ikeda, A. Ishikita, T. Tadokoro, N. Enzan, et al. 2019. Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway. Scientific Reports 9: 9850. https://doi.org/10.1038/s41598-019-46367-6.
Article CAS PubMed PubMed Central Google Scholar
Luu, A.Z., B. Chowdhury, M. Al-Omran, H. Teoh, D.A. Hess, and S. Verma. 2018. Role of endothelium in doxorubicin-induced cardiomyopathy. JACC. Basic to Translational Science 3: 861–870. https://doi.org/10.1016/j.jacbts.2018.06.005.
Article PubMed PubMed Central Google Scholar
Chen, R., M. Niu, H. Xin, and Y. He. 2023. Targeting mitochondrial dynamics proteins for the treatment of doxorubicin-induced cardiotoxicity. Frontiers in Molecular Biosciences 10: 1241225. https://doi.org/10.3389/fmolb.2023.1241225.
Article CAS PubMed PubMed Central Google Scholar
Octavia, Y., C.G. Tocchetti, K.L. Gabrielson, S. Janssens, H.J. Crijns, and A.L. Moens. 2012. Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies. Journal of Molecular and Cellular Cardiology 52: 1213–1225. https://doi.org/10.1016/j.yjmcc.2012.03.006.
Article CAS PubMed Google Scholar
Belger, C., C. Abrahams, A. Imamdin, and S. Lecour. 2024. Doxorubicin-induced cardiotoxicity and risk factors. International Journal of Cardiology Heart and Vasculature 50: 101332–101332.
Badr, A.M., and Y.F. Mahran. 2020. Notch pathway and its role in cardiovascular system: Review. Systematic Reviews in Pharmacy 11 (10): 342–349. https://doi.org/10.31838/srp.2020.10.56.
Perrimon, N., C. Pitsouli, and B.-Z. Shilo. 2012. Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harbor Perspectives in Biology 4: a005975. https://doi.org/10.1101/cshperspect.a005975.
Article CAS PubMed PubMed Central Google Scholar
Sun, J., M. Dong, X. Xiang, S. Zhang, and D. Wen. 2024. Notch signaling and targeted therapy in non-small cell lung cancer. Cancer Letters 216647. https://doi.org/10.1016/j.canlet.2024.216647.
Kopan, R. 2012. Notch signaling. Cold Spring Harbor Perspectives in Biology 4: a011213. https://doi.org/10.1101/cshperspect.a01121.
Article CAS PubMed PubMed Central Google Scholar
Huang, Q., J. Li, J. Zheng, and A. Wei. 2019. The carcinogenic role of the notch signaling pathway in the development of hepatocellular carcinoma. Journal of Cancer 10: 1570–1579. https://doi.org/10.7150/jca.26847.
Article CAS PubMed PubMed Central Google Scholar
Golde, T.E., E.H. Koo, K.M. Felsenstein, B.A. Osborne, and L. Miele. 2013. γ-Secretase inhibitors and modulators. Biochimica Et Biophysica Acta 1828: 2898–2907. https://doi.org/10.1016/j.bbamem.2013.06.005.
Article CAS PubMed Google Scholar
Pandey, P., F. Khan, M. Choi, S.K. Singh, H.N. Kang, M.N. Park, S.-G. Ko, S.K. Sahu, R. Mazumder, and B. Kim. 2023. Review deciphering potent therapeutic approaches targeting Notch signaling pathway in breast cancer. Biomedicine and Pharmacotherapy Biomedecine and Pharmacotherapie 164: 114938. https://doi.org/10.1016/j.biopha.2023.114938.
Lawal B., A.T. Wu, C.H. Chen, T.A. George, and S.Y. Wu. 2023. Identification of INFG/STAT1/NOTCH3 as γ-Mangostin’s potential targets for overcoming doxorubicin resistance and reducing cancer-associated fibroblasts in triple-negative breast cancer. Biomedicine and Pharmacotherapy Biomedecine and Pharmacotherapie 163: 114800. https://doi.org/10.1016/j.biopha.2023.114800.
Mei, H., Y. Ling, P. Ji, J. Yang, S. Fang, W. Guo, Y. Liu, and X. Chen. 2015. Doxorubicin activates the Notch signaling pathway in osteosarcoma. Oncology Letters 9: 2905–2909. https://doi.org/10.3892/ol.2015.3135.
Article CAS PubMed PubMed Central Google Scholar
Tian, T., F. Xiao, L. Jun, Z. Ruan, Y. Kejun Nan, Yao and Yujuan Yang. 2018. MicroRNA-760 Inhibits doxorubicin resistance in hepatocellular carcinoma through regulating Notch1/Hes1-PTEN/Akt signaling pathway. Journal of Biochemical and Molecular Toxicology 32: e22167. https://doi.org/10.1002/jbt.22167.
Article CAS PubMed Google Scholar
Vaish, V., J. Kim, and M. Shim. 2017. Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells. Oncotarget 8: 53262–53275. https://doi.org/10.18632/oncotarget.18391.
Article PubMed PubMed Central Google Scholar
BeLow, M., and C. Osipo. 2020. Notch signaling in breast cancer: A role in drug resistance. Cells 9: 2204. https://doi.org/10.3390/cells9102204.
Article CAS PubMed PubMed Central Google Scholar
Venkatesh, V., R. Nataraj, G.S. Thangaraj, M. Karthikeyan, A. Gnanasekaran, S.B. Kaginelli, G. Kuppanna, C.G. Kallappa, and K.M. Basalingappa. 2018. Targeting Notch signalling pathway of cancer stem cells. Stem Cell Investigation 5. China: 5. https://doi.org/10.21037/sci.2018.02.02.
Øie, E., W.J. Sandberg, M.S. Ahmed, A. Yndestad, O.D. Lærum, H. Attramadal, P. Aukrust, and H.G. Eiken. 2010. Activation of Notch signaling in cardiomyocytes during post-infarction remodeling. Scandinavian Cardiovascular Journal: SCJ 44: 359–366. https://doi.org/10.3109/14017431.2010.511256.
Article CAS PubMed Google Scholar
Gude, N., and M. Sussman. 2012. Notch signaling and cardiac repair. Journal of Molecular and Cellular Cardiology 52: 1226–1232. https://doi.org/10.1016/j.yjmcc.2012.03.007.
Article CAS PubMed PubMed Central Google Scholar
Gude, N.A., G. Emmanuel, W. Weitao, C.T. Cottage, K. Fischer, P. Quijada, J.A. Muraski, et al. 2008. Activation of Notch-mediated protective signaling in the myocardium. Circulation Research 102: 1025–1035. https://doi.org/10.1161/CIRCRESAHA.107.164749.
Article CAS PubMed PubMed Central Google Scholar
Kratsios, P., C. Catela, E. Salimova, M. Huth, V. Berno, N. Rosenthal, and F. Mourkioti. 2010. Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. Circulation Research 106: 559–572. https://doi.org/10.1161/CIRCRESAHA.109.203034.
Article CAS PubMed Google Scholar
Rizzo, P., D. Mele, C. Caliceti, M. Pannella, C. Fortini, A.G. Clementz, M.B. Morelli, G. Aquila, P. Ameri, and R. Ferrari. 2014. The role of notch in the cardiovascular system: Potential adverse effects of investigational notch inhibitors. Frontiers in Oncology 4: 384. https://doi.org/10.3389/fonc.2014.00384.
Campa, V.M., R. Gutiérrez-Lanza, F. Cerignoli, R. Díaz-Trelles, B. Nelson, T. Tsuji, M. Barcova, W. Jiang, and M. Mercola. 2008. Notch activates cell cycle reentry and progression in quiescent cardiomyocytes. The Journal of Cell Biology 183: 129–141. https://doi.org/10.1083/jcb.200806104.
Article CAS PubMed PubMed Central Google Scholar
Zheng, J., S. Zhang, and T. Wang. 2019. Expression of Notch-1 and nuclear factor-κB signal pathway in myocardial cells of coronary heart disease rats. Experimental and Therapeutic Medicine 17: 1587–1592. https://doi.org/10.3892/etm.2018.7123.
Article CAS PubMed Google Scholar
Milano, J., J. McKay, C. Dagenais, L. Foster-Brown, F. Pognan, R. Gadient, R.T. Jacobs, A. Zacco, B. Greenberg, and P.J. Ciaccio. 2004. Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicological Sciences: An Official Journal of the Society of Toxicology 82: 341–358. https://doi.org/10.1093/toxsci/kfh254.
Article CAS PubMed Google Scholar
Mantawy, E.M., W.M. El-Bakly, A. Esmat, A.M. Badr, and E. El-Demerdash. 2014. Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis. European Journal of Pharmacology 728. https://doi.org/10.1016/j.ejphar.2014.01.065.
Mathias, L.M., B. Simões, P.H.C. Alegre, I. de Oliveira, F. Dos Santos, T. Bachiega, A.M. Figueiredo, F. Chiuso-Minicucci, A.A. Fernandes, et al. 2019. Euterpe oleracea mart. (Açai) supplementation attenuates acute
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