Braun J, Sieper J. Ankylosing spondylitis. Lancet. 2007;369(9570):1379–90.

Article  PubMed  Google Scholar 

Zhang X, Sun Z, Zhou A, Tao L, Chen Y, Shi X, et al. Association between infections and risk of ankylosing spondylitis: a systematic review and meta-analysis. Front Immunol. 2021;12:768741.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Hwang MC, Ridley L, Reveille JD. Ankylosing spondylitis risk factors: a systematic literature review. Clin Rheumatol. 2021;40(8):3079–93.

Article  PubMed  PubMed Central  Google Scholar 

Song ZY, Yuan D, Zhang SX. Role of the microbiome and its metabolites in ankylosing spondylitis. Front Immunol. 2022;13:1010572.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Tavasolian F, Lively S, Pastrello C, Tang M, Lim M, Pacheco A, et al. Proteomic and genomic profiling of plasma exosomes from patients with ankylosing spondylitis. Ann Rheum Dis. 2023;82(11):1429–43.

Article  PubMed  CAS  Google Scholar 

Wang H, Luo F, Shao X, Gao Y, Jiang N, Jia C, et al. Integrated proteomics and single-cell mass cytometry analysis dissects the immune landscape of ankylosing spondylitis. Anal Chem. 2023;95(19):7702–14.

Article  PubMed  CAS  Google Scholar 

Ferkingstad E, Sulem P, Atlason BA, Sveinbjornsson G, Magnusson MI, Styrmisdottir EL, et al. Large-scale integration of the plasma proteome with genetics and disease. Nat Genet. 2021;53(12):1712–21.

Article  PubMed  CAS  Google Scholar 

van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984;27(4):361–8.

Article  PubMed  Google Scholar 

Emdin CA, Khera AV, Kathiresan S. Mendelian randomization. JAMA. 2017;318(19):1925–6.

Article  PubMed  Google Scholar 

Bowden J, Del Greco MF, Minelli C, Davey Smith G, Sheehan NA, Thompson JR. Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic. Int J Epidemiol. 2016;45(6):1961–74.

PubMed  PubMed Central  Google Scholar 

Pierce BL, Ahsan H, Vanderweele TJ. Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants. Int J Epidemiol. 2011;40(3):740–52.

Article  PubMed  Google Scholar 

Bowden J, Davey Smith G, Burgess S. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol. 2015;44(2):512–25.

Article  PubMed  PubMed Central  Google Scholar 

Bowden J, Holmes MV. Meta-analysis and Mendelian randomization: a review. Res Synth Methods. 2019;10(4):486–96.

Article  PubMed  PubMed Central  Google Scholar 

Verbanck M, Chen CY, Neale B, Do R. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018;50(5):693–8.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Cai J, Wei Z, Chen M, He L, Wang H, Li M, et al. Socioeconomic status, individual behaviors and risk for mental disorders: a Mendelian randomization study. Eur Psychiatry. 2022;65(1):e28.

Article  PubMed  PubMed Central  Google Scholar 

Ziegenhain C, Vieth B, Parekh S, Reinius B, Guillaumet-Adkins A, Smets M, et al. Comparative analysis of single-cell RNA sequencing methods. Mol Cell. 2017;65(4):631-43 e4.

Article  PubMed  CAS  Google Scholar 

Qu HQ, Kao C, Hakonarson H. Single-cell RNA sequencing technology landscape in 2023. Stem Cells. 2024;42(1):1–12.

Article  PubMed  Google Scholar 

Butler A, Hoffman P, Smibert P, Papalexi E, Satija R. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nat Biotechnol. 2018;36(5):411–20.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, et al. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019;20(2):163–72.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Byrne EM, Yang J, Wray NR. Inference in psychiatry via 2-sample Mendelian randomization-from association to causal pathway? JAMA Psychiat. 2017;74(12):1191–2.

Article  Google Scholar 

Qin Y, Meng X, Wang M, Liang W, Xu R, Chen J, et al. Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation. J Clin Invest. 2023;133(20):e161935.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Mathieu NA, Paparisto E, Barr SD, Spratt DE. HERC5 and the ISGylation pathway: critical modulators of the antiviral immune response. Viruses. 2021;13(6):1102.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Chu L, Qian L, Chen Y, Duan S, Ding M, Sun W, et al. HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity. Cell Rep. 2024;43(3):113870.

Article  PubMed  CAS  Google Scholar 

Liu C, Li L, Hou G, Lu Y, Gao M, Zhang L. HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration. Life Sci. 2022;303:120692.

Article  PubMed  CAS  Google Scholar 

Tang J, Yang Q, Cui Q, Zhang D, Kong D, Liao X, et al. Weighted gene correlation network analysis identifies RSAD2, HERC5, and CCL8 as prognostic candidates for breast cancer. J Cell Physiol. 2020;235(1):394–407.

Article  PubMed  CAS  Google Scholar 

De Leon-Oliva D, Garcia-Montero C, Fraile-Martinez O, Boaru DL, Garcia-Puente L, Rios-Parra A, et al. AIF1: function and connection with inflammatory diseases. Biology (Basel). 2023;12(5):694.

PubMed  PubMed Central  Google Scholar 

Sikora M, Kopec B, Piotrowska K, Pawlik A. Role of allograft inflammatory factor-1 in pathogenesis of diseases. Immunol Lett. 2020;218:1–4.

Article  PubMed  CAS  Google Scholar 

Zong C, Meng Y, Ye F, Yang X, Li R, Jiang J, et al. AIF1 + CSF1R + MSCs, induced by TNF-alpha, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis. Hepatology. 2023;78(2):434–51.

PubMed  Google Scholar 

Egana-Gorrono L, Chinnasamy P, Casimiro I, Almonte VM, Parikh D, Oliveira-Paula GH, et al. Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019;289:184–94.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Piotrowska K, Sluczanowska-Glabowska S, Kurzawski M, Dziedziejko V, Kopytko P, Paczkowska E, et al. Over-expression of allograft inflammatory factor-1 (AIF-1) in patients with rheumatoid arthritis. Biomolecules. 2020;10(7):1064.

Article  PubMed  CAS  PubMed Central  Google Scholar 

Zhao JW, Zhao WY, Cui XH, Xing L, Shi JC, Yu L. The role of the mitochondrial ribosomal protein family in detecting hepatocellular carcinoma and predicting prognosis, immune features, and drug sensitivity. Clin Transl Oncol. 2024;26(2):496–514.

Article  PubMed  CAS