Penack O, Marchetti M, Ruutu T, Aljurf M, Bacigalupo A, Bonifazi F, et al. Prophylaxis and management of graft versus host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation. Lancet Haematol. 2020;7:e157–e167.

Article  PubMed  Google Scholar 

Ponce DM, Politikos I, Alousi A, Carpenter PA, Milano F, MacMillan ML, et al. Guidelines for the prevention and management of graft-versus-host disease after cord blood transplantation. Transpl Cell Ther. 2021;27:540–4.

Article  CAS  Google Scholar 

Bacigalupo A, Milone G, Cupri A, Severino A, Fagioli F, Berger M, et al. Steroid treatment of acute graft- versus -host disease grade I: a randomized trial. Haematologica. 2017;102:2125–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

MacMillan ML, Robin M, Harris AC, DeFor TE, Martin PJ, Alousi A, et al. A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality. Biol Blood Marrow Transpl. 2015;21:761–7.

Article  Google Scholar 

Malard F, Huang XJ, Sim JPY. Treatment and unmet needs in steroid-refractory acute graft-versus-host disease. Leukemia. 2020;34:1229–40.

Article  PubMed  PubMed Central  Google Scholar 

MacMillan M, DeFor T, Weisdorf D. What predicts high risk acute graft‐versus‐host disease (GVHD) at onset?: identification of those at highest risk by a novel acute GVHD risk score. Br J Haematol. 2012;157:732–41.

Martin P, Schoch G, Fisher L, Byers V, Anasetti C, Appelbaum F, et al. A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment. Blood. 1990;76:1464–72.

Article  CAS  PubMed  Google Scholar 

Cragg L, Blazar BR, Defor T, Kolatker N, Miller W, Kersey J, et al. A randomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease. Biol Blood Marrow Transpl. 2000;6:441–7.

Article  CAS  Google Scholar 

Weisdorf D, Haake R, Blazar B, Miller W, McGlave P, Ramsay N, et al. Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood. 1990;75:1024–30.

Article  CAS  PubMed  Google Scholar 

Murata M, Nakasone H, Kanda J, Nakane T, Furukawa T, Fukuda T, et al. Clinical factors predicting the response of acute graft-versus-host disease to corticosteroid therapy: an analysis from the GVHD Working Group of the Japan Society for Hematopoietic Cell Transplantation. Biol Blood Marrow Transpl J Am Soc Blood Marrow Transpl. 2013;19:1183–9.

Article  CAS  Google Scholar 

Konuma T, Kanda J, Inamoto Y, Hayashi H, Kobayashi S, Uchida N, et al. Improvement of early mortality in single‐unit cord blood transplantation for Japanese adults from 1998 to 2017. Am J Hematol. 2020;95:343–53.

Article  CAS  PubMed  Google Scholar 

Konuma T, Mizuno S, Kondo T, Arai Y, Uchida N, Takahashi S, et al. Improved trends in survival and engraftment after single cord blood transplantation for adult acute myeloid leukemia. Blood Cancer J. 2022;12:81.

Article  PubMed  PubMed Central  Google Scholar 

Sugita J, Kawashima N, Fujisaki T, Kakihana K, Ota S, Matsuo K, et al. HLA-haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide after busulfan-containing reduced-intensity conditioning. Biol Blood Marrow Transpl. 2015;21:1646–52.

Article  Google Scholar 

Sugita J, Kamimura T, Ishikawa T, Ota S, Eto T, Kuroha T, et al. Reduced dose of posttransplant cyclophosphamide in HLA-haploidentical peripheral blood stem cell transplantation. Bone Marrow Transpl. 2021;56:596–604.

Article  CAS  Google Scholar 

Przepiorka D, Weisdorf D, Martin P, Klingemann HG, Beatty P, Hows J, et al. 1994 consensus conference on acute GVHD grading. Bone Marrow Transpl. 1995;15:825–8.

CAS  Google Scholar 

Harris AC, Young R, Devine S, Hogan WJ, Ayuk F, Bunworasate U, et al. International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium. Biol Blood Marrow Transpl. 2016;22:4–10.

Article  Google Scholar 

Sorror ML, Maris MB, Storb R, Baron F, Sandmaier BM, Maloney DG, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005;106:2912–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Giralt S, Ballen K, Rizzo D, Bacigalupo A, Horowitz M, Pasquini M, et al. Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research. Biol Blood Marrow Transpl J Am Soc Blood Marrow Transpl. 2009;15:367–9.

Article  Google Scholar 

Bacigalupo A, Ballen K, Rizzo D, Giralt S, Lazarus H, Ho V, et al. Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transpl J Am Soc Blood Marrow Transpl. 2009;15:1628–33.

Article  Google Scholar 

Mancusi A, Ruggeri L, Velardi A. Haploidentical hematopoietic transplantation for the cure of leukemia: from its biology to clinical translation. Blood. 2016;128:2616–23.

Article  CAS  PubMed  Google Scholar 

Ponce DM, Gonzales A, Lubin M, Castro-Malaspina H, Giralt S, Goldberg JD, et al. Graft-versus-Host Disease after Double-Unit Cord Blood Transplantation Has Unique Features and an Association with Engrafting Unit-to-Recipient HLA Match. Biol Blood Marrow Transpl. 2013;19:904–11.

Article  CAS  Google Scholar 

MacMillan ML, DeFor TE, Holtan SG, Rashidi A, Blazar BR, Weisdorf DJ. Validation of Minnesota acute graft- versus -host disease Risk Score. Haematologica. 2020;105:519–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

MacMillan M, Weisdorf D, Brunstein C, Cao Q, DeFor T, Verneris M, et al. Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors. Blood. 2009;113:2410–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mielcarek M, Storer B, Boeckh M, Carpenter P, McDonald G, Deeg H, et al. Initial therapy of acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes. Blood. 2009;113:2888–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mielcarek M, Furlong T, Storer BE, Green ML, McDonald GB, Carpenter PA, et al. Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial. Haematologica. 2015;100:842–8.

Article  CAS  PubMed  PubMed Central  Google Scholar