Von Lilienfeld-Toal M, Wagener J, Einsele H, et al. Invasive fungal infection. Dtsch Arztebl Int. 2019;116(16):271–8. https://doi.org/10.3238/arztebl.2019.0271.
Lass-Flörl C, Steixner S. The changing epidemiology of fungal infections. Mol Aspects Med. 2023;94:101215. https://doi.org/10.1016/j.mam.2023.101215.
Article PubMed CAS Google Scholar
Fang W, Wu J, Cheng M, et al. Diagnosis of invasive fungal infections: challenges and recent developments. J Biomed Sci. 2023;30(1):42. https://doi.org/10.1186/s12929-023-00926-2.
Article PubMed PubMed Central CAS Google Scholar
Sprute R, Nacov JA, Neofytos D, et al. Antifungal prophylaxis and pre-emptive therapy: when and how? Mol Aspects Med. 2023;92: 101190. https://doi.org/10.1016/j.mam.2023.101190.
Article PubMed CAS Google Scholar
Vitiello A, Ferrara F, Boccellino M, et al. Antifungal drug resistance: an emergent health threat. Biomedicines. 2023;11(4):1063. https://doi.org/10.3390/biomedicines11041063.
Article PubMed PubMed Central CAS Google Scholar
Wu S, Song R, Liu T, et al. Antifungal therapy: novel drug delivery strategies driven by new targets. Adv Drug Deliv Rev. 2023;199:114967. https://doi.org/10.1016/j.addr.2023.114967.
Article PubMed CAS Google Scholar
Soldi LR, Coelho YNB, Paranhos LR, et al. The impact of antifungal prophylaxis in patients diagnosed with acute leukemias undergoing induction chemotherapy: a systematic review and meta-analysis. Clin Exp Med. 2023;23(7):3231–49. https://doi.org/10.1007/s10238-023-01062-9.
Article PubMed CAS Google Scholar
Carmo A, Rocha M, Pereirinha P, et al. Antifungals: from pharmacokinetics to clinical practice. Antibiotics (Basel). 2023;12(5):884. https://doi.org/10.3390/antibiotics12050884.
Article PubMed CAS Google Scholar
Chen L, Krekels EHJ, Verweij PE, et al. Pharmacokinetics and pharmacodynamics of posaconazole. Drugs. 2020;80(7):671–95. https://doi.org/10.1007/s40265-020-01306-y.
Article PubMed PubMed Central CAS Google Scholar
Chen L, Krekels EHJ, Heijnen AR, et al. An integrated population pharmacokinetic analysis for posaconazole oral suspension, delayed-release tablet, and intravenous infusion in healthy volunteers. Drugs. 2023;83(1):75–86. https://doi.org/10.1007/s40265-022-01819-8.
Article PubMed CAS Google Scholar
Stemler J, Mellinghoff SC, Khodamoradi Y, et al. Primary prophylaxis of invasive fungal diseases in patients with haematological malignancies: 2022 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO). J Antimicrob Chemother. 2023;78(8):1813–26. https://doi.org/10.1093/jac/dkad143.
Article PubMed PubMed Central CAS Google Scholar
Wong TY, Loo YS, Veettil SK, et al. Efficacy and safety of posaconazole for the prevention of invasive fungal infections in immunocompromised patients: a systematic review with meta-analysis and trial sequential analysis. Sci Rep. 2020;10(1):14575. https://doi.org/10.1038/s41598-020-71571-0.
Article PubMed PubMed Central CAS Google Scholar
Maertens JA, Girmenia C, Brüggemann RJ, et al. European guidelines for primary antifungal prophylaxis in adult haematology patients: summary of the updated recommendations from the European Conference on Infections in Leukaemia. J Antimicrob Chemother. 2018;73(12):3221–30. https://doi.org/10.1093/jac/dky286.
Van Daele R, Spriet I, Maertens J. Posaconazole in prophylaxis and treatment of invasive fungal infections: a pharmacokinetic, pharmacodyn amic and clinical evaluation. Expert Opin Drug Metab Toxicol. 2020;16(7):539–50. https://doi.org/10.1080/17425255.2020.1764939.
Dolton MJ, Ray JE, Chen SC, et al. Multicenter study of posaconazole therapeutic drug monitoring: exposure–response relationship and factors affecting concentration. Antimicrob Agents Chemother. 2012;56(11):5503–10. https://doi.org/10.1128/AAC.00802-12.
Article PubMed PubMed Central CAS Google Scholar
Kably B, Launay M, Derobertmasure A, et al. Antifungal drugs TDM: trends and update. Ther Drug Monit. 2022;44(1):166–97. https://doi.org/10.1097/FTD.0000000000000952.
McCreary EK, Davis MR, Narayanan N, et al. Utility of triazole antifungal therapeutic drug monitoring: Insights from the Society of Infectious Diseases Pharmacists: endorsed by the Mycoses Study Group Education and Research Consortium. Pharmacotherapy. 2023;43(10):1043–50. https://doi.org/10.1002/phar.2850.
Article PubMed CAS Google Scholar
Gómez-López A. Antifungal therapeutic drug monitoring: focus on drugs without a clear recommendation. Clin Microbiol Infect. 2020;26(11):1481–7. https://doi.org/10.1016/j.cmi.2020.05.037.
Chen L, Wang Y, Zhang T, et al. Utility of posaconazole therapeutic drug monitoring and assessment of plasma concentration threshold for effective prophylaxis of invasive fungal infections: a meta-analysis with trial sequential analysis. BMC Infect Dis. 2018;18(1):155. https://doi.org/10.1186/s12879-018-3055-3.
Article PubMed PubMed Central Google Scholar
Jia MM, Zhang QW, Qin ZF, et al. Deciphering the relationship between the trough concentration of posaconazole and its efficacy and safety in Chinese patients with hematological disorders. Front Pharmacol. 2020;11:575463. https://doi.org/10.3389/fphar.2020.575463.
Article PubMed PubMed Central CAS Google Scholar
Li W, Xia F, Zhou H, et al. Efficacy of posaconazole prophylaxis for fungal disease in hematology patients treated with chemotherapy and transplantation: an open-label, prospective, observational study. Front Microbiol. 2020;11:349. https://doi.org/10.3389/fmicb.2020.00349.
Article PubMed PubMed Central Google Scholar
Chen L, Krekels EHJ, Dong Y, et al. Meta-pharmacokinetic analysis of posaconazole following dosing of oral suspension, delayed-release tablet, and intravenous infusion in patients vs. healthy volunteers: Impact of clinical characteristics and race. Int J Antimicrob Agents. 2023;62(6):106995. https://doi.org/10.1016/j.ijantimicag.2023.106995.
Article PubMed CAS Google Scholar
Donnelly JP, Chen SC, Kauffman CA, et al. Revision and update of the consensus definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. Clin Infect Dis. 2020;71(6):1367–76. https://doi.org/10.1093/cid/ciz1008.
National Institute of Diabetes and Digestive and Kidney Diseases. Adverse Drug Reaction Probability Scale (Naranjo) in Drug Induced Liver Injury. LiverTox: Clinical and Research Information on Drug-Induced Liver [Internet]. [Updated 2019 May 4]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548069/
Kraljevic M, Khanna N, Medinger M, et al. Clinical considerations on posaconazole administration and therapeutic drug monitoring in allogeneic hematopoietic cell transplant recipients. Med Mycol. 2021;59(7):701–11. https://doi.org/10.1093/mmy/myaa106.
Article PubMed CAS Google Scholar
Reynolds G, Urbancic KF, Fong CY, et al. Invasive fungal infection following venetoclax and posaconazole co-administration. Br J Haematol. 2023;203(4):593–8. https://doi.org/10.1111/bjh.19116.
Article PubMed CAS Google Scholar
Suh HJ, Yoon SH, Yu KS, et al. The genetic polymorphism UGT1A4*3 is associated with low posaconazole plasma concentrations in hematological malignancy patients receiving the oral suspension. Antimicrob Agents Chemother. 2018;62(7):e02230–e2317. https://doi.org/10.1128/AAC.02230-17.
Article PubMed PubMed Central CAS Google Scholar
Cojutti PG, Candoni A, Lazzarotto D, et al. Co-administration of proton pump inhibitors and/or of steroids may be a risk factor for low trough concentrations of posaconazole delayed-released tablets in adult patients with haematological malignancies. Br J Clin Pharmacol. 2018;84(11):2544–50. https://doi.org/10.1111/bcp.13707.
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