Comparison of Muscle Growth and Dynamic Strength Adaptations Induced by Unilateral and Bilateral Resistance Training: A Systematic Review and Meta-analysis

Kassiano W, Nunes JP, Costa B, Ribeiro AS, Schoenfeld BJ, Cyrino ES. Does varying resistance exercises promote superior muscle hypertrophy and strength gains? A systematic review. J Strength Cond Res. 2022;36(6):1753–62. https://doi.org/10.1519/JSC.0000000000004258. (PMID: 35438660).

Article  PubMed  Google Scholar 

Mullican K, Nijem R. Are unilateral exercises more effective than bilateral exercises? Strength Cond J. 2016;38(1):68–70. https://doi.org/10.1519/SSC.0000000000000181.

Article  Google Scholar 

Nijem RM, Galpin AJ. Unilateral versus bilateral exercise and the role of the bilateral force deficit. Strength Cond J. 2014;36(5):113–8. https://doi.org/10.1519/SSC.0000000000000085.

Article  Google Scholar 

Rossman MJ, Venturelli M, McDaniel J, Amann M, Richardson RS. Muscle mass and peripheral fatigue: a potential role for afferent feedback? Acta Physiol (Oxf). 2012;206(4):242–50. https://doi.org/10.1111/j.1748-1716.2012.02471.x. (PMID: 22762286).

Article  CAS  PubMed  Google Scholar 

Rossman MJ, Garten RS, Venturelli M, Amann M, Richardson RS. The role of active muscle mass in determining the magnitude of peripheral fatigue during dynamic exercise. Am J Physiol Regul Integr Comp Physiol. 2014;306(12):R934–40. https://doi.org/10.1152/ajpregu.00043.2014. (PMID: 24740653).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abbiss CR, Karagounis LG, Laursen PB, Peiffer JJ, Martin DT, Hawley JA, et al. Single-leg cycle training is superior to double-leg cycling in improving the oxidative potential and metabolic profile of trained skeletal muscle. J Appl Physiol (1985). 2011;110(5):1248–55. https://doi.org/10.1152/japplphysiol.01247.2010. (PMID: 21330612).

Article  CAS  PubMed  Google Scholar 

Zhang J, Iannetta D, Alzeeby M, MacInnis MJ, Aboodarda SJ. Exercising muscle mass influences neuromuscular, cardiorespiratory, and perceptual responses during and following ramp-incremental cycling to task failure. Am J Physiol Regul Integr Comp Physiol. 2021;321(2):R238–49. https://doi.org/10.1152/ajpregu.00286.2020. (PMID: 34189949).

Article  CAS  PubMed  Google Scholar 

Matos-Santos L, Farinatti P, Borjes JP, Massaferri R, Monteiro W. Cardiovascular responses to resistance exercise performed with large and small muscle mass. Int J Sports Med. 2017;38(12):883–9. https://doi.org/10.1055/s-0043-116671. (PMID: 28926870).

Article  PubMed  Google Scholar 

De Oliveira JLS, Lima LCR, Barreto RV, Kassiano W, Neto JOV, Filho JCCN, et al. Cardiovascular responses to unilateral, bilateral, upper, and lower limbs resistance exercises. Int J Exerc Sci. 2023;16(2):1154–64. (PMID: 38288401).

PubMed  Google Scholar 

Matkowski B, Place N, Martin A, Lepers R. Neuromuscular fatigue differs following unilateral vs bilateral sustained submaximal contractions. Scand J Med Sci Sports. 2011;21(2):268–76. https://doi.org/10.1111/j.1600-0838.2009.01040.x. (PMID: 19903318).

Article  CAS  PubMed  Google Scholar 

Gandevia SC. Spinal and supraspinal factors in human muscle fatigue. Physiol Rev. 2001;81(4):1725–89. https://doi.org/10.1152/physrev.2001.81.4.1725. (PMID: 11581501).

Article  CAS  PubMed  Google Scholar 

Botton CE, Radaelli R, Wilhelm EN, Rech A, Brown LE, Pinto RS. Neuromuscular adaptations to unilateral vs. bilateral strength training in women. J Strength Cond Res. 2016;30(7):1924–32. https://doi.org/10.1519/JSC.0000000000001125. (PMID: 26348920).

Article  PubMed  Google Scholar 

Janzen CL, Chilibeck PD, Davison KS. The effect of unilateral and bilateral strength training on the bilateral deficit and lean tissue mass in post-menopausal women. Eur J Appl Physiol. 2006;97(3):253–60. https://doi.org/10.1007/s00421-006-0165-1. (PMID: 16568338).

Article  PubMed  Google Scholar 

Zhang W, Chen X, Xu K, Xie H, Li D, Ding S, et al. Effect of unilateral training and bilateral training on physical performance: a meta-analysis. Front Physiol. 2023;14:1128250. https://doi.org/10.3389/fphys.2023.1128250. (PMID: 37123275).

Article  PubMed  PubMed Central  Google Scholar 

Liao KF, Nassis GP, Bishop C, Yang W, Bian C, Li YM. Effects of unilateral vs. bilateral resistance training interventions on measures of strength, jump, linear and change of direction speed: a systematic review and meta-analysis. Biol Sport. 2022;39(3):485–97. https://doi.org/10.5114/biolsport.2022.107024. (PMID: 35959319).

Article  PubMed  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71. https://doi.org/10.1136/bmj.n71. (PMID: 33782057).

Article  PubMed  PubMed Central  Google Scholar 

Ardern CL, Büttner F, Andrade R, Weir A, Ashe MC, Holden S, et al. Implementing the 27 PRISMA 2020 Statement items for systematic reviews in the sport and exercise medicine, musculoskeletal rehabilitation and sports science fields: the PERSiST (implementing Prisma in Exercise, Rehabilitation, Sport medicine and SporTs science) guidance. Br J Sports Med. 2022;56(4):175–95. https://doi.org/10.1136/bjsports-2021-103987. (PMID: 34625401).

Article  PubMed  Google Scholar 

McGuinness LA, Higgins JPT. Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods. 2021;12(1):55–61. https://doi.org/10.1002/jrsm.1411. (PMID: 32336025).

Article  PubMed  Google Scholar 

Dankel SJ, Loenneke JP. Effect sizes for paired data should use the change score variability rather than the pre-test variability. J Strength Cond Res. 2021;35(6):1773–8. https://doi.org/10.1519/JSC.0000000000002946. (PMID: 30358698).

Article  PubMed  Google Scholar 

Caldwell A, Vigotsky AD. A case against default effect sizes in sport and exercise science. PeerJ. 2020;8:e10314. https://doi.org/10.7717/peerj.10314. (PMID: 33194448).

Article  PubMed  PubMed Central  Google Scholar 

Borenstein M. Introduction to meta-analysis. Chichester: John Wiley & Sons; 2009.

Book  Google Scholar 

Fisher Z, Tipton E, Zhipeng H. Robumeta: robust variance meta-regression. R package version 2.1. https://www.CRANR-projectorg/package=robumeta. 2023.

Hedges LV, Tipton E, Johnson MC. Robust variance estimation in meta-regression with dependent effect size estimates. Res Synth Methods. 2010;1(1):39–65. https://doi.org/10.1002/jrsm.5. (PMID: 26056092).

Article  PubMed  Google Scholar 

Appleby BB, Cormack SJ, Newton RU. Unilateral and bilateral lower-body resistance training does not transfer equally to sprint and change of direction performance. J Strength Cond Res. 2020;34(1):54–64. https://doi.org/10.1519/JSC.0000000000003035. (PMID: 30844983).

Article  PubMed  Google Scholar 

Krajewski KT, Bansbach HM, McLean L, McKenzie C, Rawcliffe A, Graham SM, et al. Effects of short-term unilateral strength training on measures of postural control when wearing “operationally relevant’’ backpack loads. J Strength Cond Res. 2020;34(10):2743–50. https://doi.org/10.1519/JSC.0000000000003794. (PMID: 32956262).

Article  PubMed  Google Scholar 

Lee ELY, Abd Malek NF, Tan K, Pratama RS, Mohamad NI, Nadzalan AM. The effects of unilateral versus bilateral resistance training on bilateral deficit, unilateral and bilateral strength adaptation among trained men. J Phys Conf Ser. 2021;1793(1): 012057. https://doi.org/10.1088/1742-6596/1793/1/012057.

Article  Google Scholar 

Ramirez-Campillo R, Sanchez-Sanchez J, Gonzalo-Skok O, Rodríguez-Fernandez A, Carretero M, Nakamura FY. Specific changes in young soccer player’s fitness after traditional bilateral vs. unilateral combined strength and plyometric training. Front Physiol. 2018;9:265. https://doi.org/10.3389/fphys.2018.00265. (PMID: 29623049).

Article  PubMed  PubMed Central  Google Scholar 

Speirs DE, Bennett MA, Finn CV, Turner AP. Unilateral vs. bilateral squat training for strength, sprints, and agility in academy rugby players. J Strength Cond Res. 2016;30(2):386–92. https://doi.org/10.1519/JSC.0000000000001096. (PMID: 26200193).

Article  PubMed  Google Scholar 

Stern D, Gonzalo-Skok O, Loturco I, Turner A, Bishop C. A comparison of bilateral vs. unilateral-biased strength and power training interventions on measures of physical performance in elite youth soccer players. J Strength Cond Res. 2020;34(8):2105–11. https://doi.org/10.1519/JSC.0000000000003659. (PMID: 32541618).

Article  PubMed  Google Scholar 

Zhao X, Turner AP, Sproule J, Phillips SM. The effect of unilateral and bilateral leg press training on lower body strength and power and athletic performance in adolescent rugby players. J Hum Kinet. 2023;86:235–46. https://doi.org/10.5114/jhk/159626. (PMID: 37181263).

Article  PubMed  PubMed Central  Google Scholar 

Jakobi JM, Chilibeck PD. Bilateral and unilateral contractions: possible differences in maximal voluntary force. Can J Appl Physiol. 2001;26(1):12–33. https://doi.org/10.1139/h01-002. (PMID: 11173667).

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