Authors Keywords: pharmacokinetics, loco-regional anaesthesia, anti-haemostatic agents Abstract

Perioperatively, patients on anti-haemostatic agents present anaesthetists with unique challenges. Besides careful consideration of the overall bleeding versus thrombosis risks, the risks versus benefits of loco-regional anaesthetic techniques must be balanced with the risks of perineural haematoma formation and neurological damage. This article reviews the pharmacokinetics of available anti-haemostatic agents in South Africa in relation to the performance of loco-regional anaesthesia.

Author Biographies SN Griessel, Stellenbosch University

Tygerberg Hospital, Stellenbosch University, South Africa

L Firfiray, Stellenbosch University

Tygerberg Hospital, Stellenbosch University, South Africa

Issue Section

Clinical reviews

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