Letter D

Dalziel’s syndrome (Dalziel’s disease)“I have pleasure in drawing your attention to this condition, which, I think, has not yet been fully described.” With these words, a Glasgow surgeon, T Kennedy Dalzeil, drew the attention of members of the British Medical Association to the intestinal disease that he called chronic interstitial enteritis. The address, accompanied by a demonstration of resected specimens, was given to the Annual Meeting of the BMA in Glasgow in July 1913. He described how in 1901 he had seen a professional colleague who had numerous attacks of colic associated with slight attacks of diarrhea, who had gone on to have an intestinal obstruction. Dalzeil’s description of the condition that later became known as Crohn’s disease was quite comprehensive. He proposed that the disease was caused by the same organisms as those responsible for chronic enteritis, Johne’s disease, in animals described a few years earlier (1895). Dalziel’s dilemma was that he could see acid-fast bacilli in the diseased animal tissues but not in the diseased human tissues.

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