Safety of non-ionic contrast media in CT examinations for out-patients: retrospective multicenter analysis of 473,482 patients

Ong MY, Koh JJ, Kothan S, Lai C (2022) The incidence and associated risk factors of contrast-induced nephropathy after contrast-enhanced computed tomography in the emergency setting: a systematic review. Life (Basel) 12(6):826.

Huynh K, Baghdanian AH, Baghdanian AA, Sun DS, Kolli KP, Zagoria RJ (2020) Updated guidelines for intravenous contrast use for CT and MRI. Emerg Radiol 27:115–126

Article  PubMed  Google Scholar 

Snaith B, Harris MA, Shinkins B et al (2019) Point of care creatinine testing in diagnostic imaging: a feasibility study within the outpatient computed tomography setting. Eur J Radiol 112:82–87

Article  PubMed  Google Scholar 

Wee NK, Tiong SC, Lee CH, H’Ng MWC (2021) Safety of a rapid outpatient hydration protocol for patients with renal impairment requiring intravenous iodinated contrast media for computed tomography. Singapore Med J 62:588–593

Article  CAS  PubMed  PubMed Central  Google Scholar 

An J, Jung H, Kwon OY et al (2019) Differences in adverse reactions among iodinated contrast media: analysis of the KAERS Database. J Allergy Clin Immunol Pract 7:2205–11

Article  CAS  PubMed  Google Scholar 

Hsieh C, Wu SC, Kosik RO, Huang YC, Chan WP (2022) Pharmacological prevention of hypersensitivity reactions caused by iodinated contrast media: a systematic review and meta-analysis. Diagnostics (Basel) 12(7):1673

Tasker F, Fleming H, McNeill G, Creamer D, Walsh S (2019) Contrast media and cutaneous reactions. Part 2: delayed hypersensitivity reactions to iodinated contrast media. Clin Exp Dermatol 44:844–60

Article  CAS  PubMed  Google Scholar 

Voltolini S, Cofini V, Murzilli F et al (2022) Hypersensitivity reactions to iodinate contrast media in Italy: a retrospective study. Characteristics of patients and risk factors. Eur Ann Allergy Clin Immunol 54:60–7

Article  CAS  PubMed  Google Scholar 

Chiu TM, Chu SY (2022) Hypersensitivity reactions to iodinated contrast media. Biomedicines 10(5):1036

Mortelé KJ, Oliva MR, Ondategui S, Ros PR, Silverman SG (2005) Universal use of nonionic iodinated contrast medium for CT: evaluation of safety in a large urban teaching hospital. AJR Am J Roentgenol. 184:31–4

Article  PubMed  Google Scholar 

Kodzwa R (2019) ACR manual on contrast media: 2018 updates. Radiol Technol 91(1):97–100

PubMed  Google Scholar 

Van der Molen AJ, Reimer P, Dekkers IA et al (2018) Post-contrast acute kidney injury - part 1: definition, clinical features, incidence, role of contrast medium and risk factors: recommendations for updated ESUR Contrast Medium Safety Committee guidelines. Eur Radiol 28(7):2845–2855

Article  PubMed  PubMed Central  Google Scholar 

Esplugas E, Cequier A, Gomez-Hospital JA, Del Blanco BG, Jara F (2002) Comparative tolerability of contrast media used for coronary interventions. Drug Saf 25:1079–98

Article  CAS  PubMed  Google Scholar 

Gharekhanloo F, Torabian S (2012) Comparison of allergic adverse effects and contrast enhancement between iodixanol and iopromide. Iran J Radiol 9:63–66

Article  PubMed  PubMed Central  Google Scholar 

Iordache AM, Docea AO, Buga AM et al (2019) The incidence of skin lesions in contrast media-induced chemical hypersensitivity. Exp Ther Med. 17:1113–24

CAS  PubMed  Google Scholar 

Lee SY, Rhee CM, Leung AM, Braverman LE, Brent GA, Pearce EN (2015) A review: radiographic iodinated contrast media-induced thyroid dysfunction. J Clin Endocrinol Metab. 100:376–83

Article  CAS  PubMed  Google Scholar 

Shin H, Taghavifar S, Salehi S, Joyce P, Gholamrezanezhad A (2021) Current comments on contrast media administration in patients with renal insufficiency. Clin Imaging 69:37–44

Article  PubMed  Google Scholar 

Zhang B, Dong Y, Liang L et al (2016) The incidence, classification, and management of acute adverse reactions to the low-osmolar iodinated contrast media Isovue and Ultravist in contrast-enhanced computed tomography scanning. Medicine (Baltimore) 95:e3170

Article  PubMed  Google Scholar 

Mikkonen R, Vehmas T, Granlund H, Kivisaari L (2000) Seasonal variation in the occurrence of late adverse skin reactions to iodine-based contrast media. Acta Radiol 41:390–393

Article  CAS  PubMed  Google Scholar 

Torres MJ, Trautmann A, Böhm I et al (2021) Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity. Allergy 76:1325–1339

Article  PubMed  Google Scholar 

Dean KE, Starikov A, Giambrone A, Hentel K, Min R, Loftus M (2015) Adverse reactions to intravenous contrast media: an unexpected discrepancy between inpatient and outpatient cohorts. Clin Imaging 39:863–5

Article  PubMed  Google Scholar 

Suh YJ, Yoon SH, Hong H et al (2019) Acute adverse reactions to nonionic iodinated contrast media: a meta-analysis. Investig Radiol 54:589–99

Article  CAS  Google Scholar 

Kim SR, Lee JH, Park KH, Park HJ, Park JW (2017) Varied incidence of immediate adverse reactions to low-osmolar non-ionic iodide radiocontrast media used in computed tomography. Clin Exp Allergy 47:106–112

Article  PubMed  Google Scholar 

Jost G, Pietsch H, Lengsfeld P, Hutter J, Sieber MA (2010) The impact of the viscosity and osmolality of iodine contrast agents on renal elimination. Investig Radiol 45:255–61

Article  Google Scholar 

Ho J, Kingston RJ, Young N, Katelaris CH, Sindhusake D (2012) Immediate hypersensitivity reactions to IV non-ionic iodinated contrast in computed tomography. Asia Pac Allergy 2:242–7

Article  PubMed  PubMed Central  Google Scholar 

Schild HH, Kuhl CK, Hubner-Steiner U, Bohm I, Speck U (2006) Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trial. Radiology 240:56–64

Article  PubMed  Google Scholar 

Li X, Liu H, Zhao L et al (2017) Clinical observation of adverse drug reactions to non-ionic iodinated contrast media in population with underlying diseases and risk factors. Br J Radiol 90:20160729

Article  PubMed  PubMed Central  Google Scholar 

Zhao F, Lei R, Yang SK et al (2019) Comparative effect of iso-osmolar versus low-osmolar contrast media on the incidence of contrast-induced acute kidney injury in diabetic patients: a systematic review and meta-analysis. Cancer Imaging 19:38

Article  PubMed  PubMed Central  Google Scholar 

Han XF, Zhang XX, Liu KM, Tan H, Zhang Q (2018) Contrast-induced nephropathy in patients with diabetes mellitus between iso- and low-osmolar contrast media: a meta-analysis of full-text prospective, randomized controlled trials. PLoS One 13:e0194330

Article  PubMed  PubMed Central  Google Scholar 

Zhang BC, Wu Q, Wang C, Li DY, Wang ZR (2014) A meta-analysis of the risk of total cardiovascular events of isosmolar iodixanol compared with low-osmolar contrast media. J Cardiol 63:260–8

Article  PubMed  Google Scholar 

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