Dierick BJH, et al. Burden and socioeconomics of asthma, allergic rhinitis, atopic dermatitis and food allergy. Expert Rev Pharmacoecon Outcomes Res. 2020;20:437–53.
Meng Y, Wang C, Zhang L. Advances and novel developments in allergic rhinitis. Allergy. 2020;75:3069–76. https://doi.org/10.1111/all.14586
Asher MI, García-Marcos L, Pearce NE, Strachan DP. Trends in worldwide asthma prevalence. Eur Respir. 2020. https://doi.org/10.1183/13993003.02094-2020.
Ober C. Asthma genetics in the post-GWAS era. Ann Am Thorac Soc. 2016;13(Suppl 1):S85-90.
Article PubMed PubMed Central Google Scholar
Renz H, et al. Gene-environment interaction in chronic disease: a European science foundation forward look. J Allergy Clin Immunol. 2011;128:S27-49.
Legaki E, Taka S, Papadopoulos NG. The complexity in DNA methylation analysis of allergic diseases. Curr Opin Allergy Clin Immunol. 2023;23:172–8.
Article CAS PubMed Google Scholar
Holliday R, Pugh JE. DNA modification mechanisms and gene activity during development. Science. 1975;187:226–32.
Article CAS PubMed Google Scholar
Compere SJ, Palmiter RD. DNA methylation controls the inducibility of the mouse metallothionein-I gene lymphoid cells. Cell. 1981;25:233–40.
Article CAS PubMed Google Scholar
Tost J. DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Mol Biotechnol. 2010;44:71–81.
Article CAS PubMed Google Scholar
Schübeler D. Function and information content of DNA methylation. Nature. 2015;517:321–6.
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 1999;99:247–57.
Article CAS PubMed Google Scholar
Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annu Rev Biochem. 2005;74:481–514.
Article CAS PubMed Google Scholar
Bourc’his D, Xu GL, Lin CS, Bollman B, Bestor TH. Dnmt3L and the establishment of maternal genomic imprints. Science. 2001;294:2536–9.
Baubec T, et al. Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation. Nature. 2015;520:243–7.
Article CAS PubMed Google Scholar
Weinberg DN, et al. The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape. Nature. 2019;573:281–6.
Article CAS PubMed PubMed Central Google Scholar
Wu H, et al. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science. 2010;329:444–8.
Article CAS PubMed PubMed Central Google Scholar
Chen Z, Yin Q, Inoue A, Zhang C, Zhang Y. Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells. Sci. 2019. https://doi.org/10.1126/sciadv.aay7246.
Article PubMed PubMed Central Google Scholar
Weinberg DN, et al. Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands. Nat Genet. 2021;53:794–800.
Article CAS PubMed PubMed Central Google Scholar
Lin CC, Chen YP, Yang WZ, Shen JCK, Yuan HS. Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res. 2020;48:3949–61.
Article CAS PubMed PubMed Central Google Scholar
Smallwood SA, et al. Dynamic CpG island methylation landscape in oocytes and preimplantation embryos. Nat Genet. 2011;43:811–4.
Article CAS PubMed PubMed Central Google Scholar
Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet. 2012;13:484–92.
Article CAS PubMed Google Scholar
Beck DB, et al. Delineation of a human mendelian disorder of the dna demethylation machinery: TET3 deficiency. Am J Hum Genet. 2020;106:234–45.
Article CAS PubMed PubMed Central Google Scholar
Gu TP, et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature. 2011;477:606–10.
Article CAS PubMed Google Scholar
Inoue A, Shen L, Dai Q, He C, Zhang Y. Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Res. 2011;21:1670–6.
Article CAS PubMed PubMed Central Google Scholar
Inoue A, Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science. 2011;334:194.
Article CAS PubMed PubMed Central Google Scholar
Tahiliani M, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324:930–5.
Article CAS PubMed PubMed Central Google Scholar
Ito S, et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science. 2011;333:1300–3.
Article CAS PubMed PubMed Central Google Scholar
Jung KH, et al. Short-term exposure to PM2.5 and vanadium and changes in asthma gene DNA methylation and lung function decrements among urban children. Respir Res. 2017. https://doi.org/10.1186/s12931-017-0550-9.
Article PubMed PubMed Central Google Scholar
Gruzieva O, et al. Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis. Environ Health Perspect. 2019;127:57012.
Plusquin M, et al. DNA methylome marks of exposure to particulate matter at three time points in early life. Environ Sci Technol. 2018;52:5427–37.
Article CAS PubMed Google Scholar
Clifford RL, et al. Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation. J Allergy Clin Immunol. 2017;139:112–21.
Comments (0)