Sarkar D, Gorai P, Pramanik A, Mondal A, Mondal N, Modak B, et al. Characterization and active component identification of Premna herbacea roxb root extract reveals anti-inflammatory effect and amelioration of imiquimod induced psoriasis via modulation of macrophage inflammatory response. Phytomedicine. 2023;119:155007. https://doi.org/10.1016/j.phymed.2023.155007.

Article  CAS  PubMed  Google Scholar 

Deng J, Tan S, Liu R, Yu W, Chen H, Tang N, et al. Chinese medicine formula PSORI-CM02 alleviates psoriatic dermatitis via M-MDSCs and Th17 crosstalk. Front Pharmacol. 2021;11:1–13.

Article  Google Scholar 

Oka T, Sugaya M, Takahashi N, Takahashi T, Shibata S, Miyagaki T, et al. CXCL17 attenuates Imiquimod-Induced psoriasis-like skin inflammation by recruiting myeloid-derived suppressor cells and regulatory T cells. J Immunol. 2017;198:3897–908.

Article  CAS  PubMed  Google Scholar 

Dhabale A, Nagpure S. Types of psoriasis and their effects on the Immune System. Cureus. 2022;14(9):e29536

PubMed  PubMed Central  Google Scholar 

Alrefai H, Muhammad K, Rudolf R, Pham DAT, Klein-Hessling S, Patra AK, et al. NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. Nat Commun. 2016;7:11724. https://doi.org/10.1038/ncomms11724.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pramanik A, Bhattacharyya S. Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment. Life Sci. 2022;305:120755. https://doi.org/10.1016/j.lfs.2022.120755.

Article  CAS  PubMed  Google Scholar 

Lim HX, Kim TS. Understanding the differentiation, expansion, recruitment and suppressive activities of myeloid-derived suppressor cells in cancers. Int J Mol Sci. 2020;21:3599.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Veglia F, Sanseviero E, Gabrilovich DI. Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity. Nat Rev Immunol. 2021. https://doi.org/10.1038/s41577-020-00490-y.

Article  PubMed  PubMed Central  Google Scholar 

Almand B, Clark JI, Nikitina E, Beynen V, English NR, Knight SC, et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol. 2001;166(1):678–89. https://doi.org/10.4049/jimmunol.166.1.678.

Article  CAS  PubMed  Google Scholar 

Marvel D, Gabrilovich DI. Myeloid-derived suppressor cells in the tumor microenvironment : expect the unexpected. J Xlin Invest. 2015;125:3356.

Article  Google Scholar 

Zhao H, Wu L, Yan G, Chen Y, Zhou M, Wu Y, et al. Inflammation and tumor progression: signaling pathways and targeted intervention. Signal Transduct Target Ther. 2021. https://doi.org/10.1038/s41392-021-00658-5.

Article  PubMed  PubMed Central  Google Scholar 

Mahanti K, Saha J, Sarkar D, Pramanik A, Chattopadhyay NR. Alteration of functionality and differentiation directed by changing gene expression patterns in myeloid-derived suppressor cells (MDSCs) in tumor microenvironment and bone marrow through early to terminal phase of tumor progression. J Leukocyte Biol. 2024;115:958–84.

Article  PubMed  Google Scholar 

Liu P, Peng C, Chen X, Wu L, Yin M, Li J. Acitretin promotes the differentiation of myeloid-derived suppressor cells in the treatment of psoriasis. Front Med. 2021;8:1–13.

Google Scholar 

Chen C, Tan L, Zhu W, Lei L, Kuang Y, Liu P, et al. Targeting myeloid-derived suppressor cells is a novel strategy for anti-psoriasis therapy.  Mediators Inflammation. 2020.

Fultang L, Panetti S, Ng M, Collins P, Graef S, Rizkalla N, et al. EBioMedicine MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers. EBioMedicine. 2019;47:235–46. https://doi.org/10.1016/j.ebiom.2019.08.025.

Article  PubMed  PubMed Central  Google Scholar 

Yang Y, Li C, Liu T, Dai X, Bazhin AV. Myeloid-derived suppressor cells in tumors: from mechanisms to antigen specificity and microenvironmental regulation.  Front Immunol. 2020;11:1–22.

CAS  Google Scholar 

Li M, Zhu D, Wang T, Xia X, Tian J, Wang S. Roles of myeloid-derived suppressor cell subpopulations in autoimmune arthritis. Front Immunol. 2018;9:1–15.

Article  Google Scholar 

Kong YY, Wilson K, Apostolopoulos V. Dendritic cells and myeloid derived suppressor cells fully responsive to stimulation via toll-like receptor 4 are rapidly induced from bone-marrow cells by granulocyte-macrophage colony-stimulating factor. Vaccines. 2020;8:522.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu S, Cao X. Interleukin-17 and its expanding biological functions. Cell Mol Immunol. 2010;7:164–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kwon HK, Kim GC, Hwang JS, Kim Y, Chae CS, Nam JH, et al. Transcription factor NFAT1 controls allergic contact hypersensitivity through regulation of activation induced cell death program. Sci Rep. 2016;6:1–15.

Article  Google Scholar 

Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol. 1997;15:707–47.

Article  CAS  PubMed  Google Scholar 

López-Rodríguez C, Aramburu J, Rakeman AS, Rao A. NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. Proc Natl Acad Sci USA. 1999;96:7214–9.

Article  PubMed  PubMed Central  Google Scholar 

Wang X, Bi Y, Xue L, Liao J, Chen X, Lu Y, et al. The calcineurin-NFAT axis controls allograft immunity in myeloid- derived suppressor cells through reprogramming T cell. Mol Cell Biol. 2015;35:598–609.

Article  PubMed  PubMed Central  Google Scholar 

Al-Daraji WI, Grant KR, Ryan K, Saxton A, Reynolds NJ. Localization of calcineurin/NFAT in human skin and psoriasis and inhibition of calcineurin/NFAT activation in human keratinocytes by cyclosporin A. J Invest Dermatol. 2002;118:779–88. https://doi.org/10.1046/j.1523-1747.2002.01709.x.

Article  CAS  PubMed  Google Scholar 

Herman A, Herman AP. Topically used herbal products for the treatment of psoriasis - mechanism of action, drug delivery, clinical studies. Planta Med. 2016;82:1447–55.

Article  CAS  PubMed  Google Scholar 

Alarami AMJ. Histopathological changes in the liver and kidney of albino mice on exposure to Insecticide. Dimethoate Int J Curr Microbiol App Sci. 2015;4:287–300.

CAS  Google Scholar 

Saha J, Sarkar D, Pramanik A, Mahanti K, Adhikary A, Bhattacharyya S. PGE2-HIF1α reciprocal induction regulates migration, phenotypic alteration and immunosuppressive capacity of macrophages in tumor microenvironment. Life Sci. 2020;253:117731. https://doi.org/10.1016/j.lfs.2020.117731.

Article  CAS  PubMed  Google Scholar 

Lu Y, Xiao Y, Yin MZ, Zhou XC, Wu LS, Chen WQ, et al. Polyethylene glycol ointment alleviates Psoriasis-Like inflammation through down-regulating the function of Th17 cells and MDSCs. Front Med. 2021;7:1–11.

Article  CAS  Google Scholar 

Pati S, Mukherjee S, Dutta S, Guin A, Roy D, Bose S, et al. Tumor-associated CD19 þ CD39 – B regulatory cells deregulate class-switch recombination to suppress antib responses. Cancer Immunol Res. 2023;11:364–80.

Article  CAS  PubMed  Google Scholar 

Yousefzadehn H, Azad FJ, Rastin M, Banihashemi M, Mahmoudi M. Expression of Th1 and Th2 cytokine and associated transcription factors in peripheral blood mononuclear cells and correlation with disease severity. Rep Biochem Mol Biol. 2017;6:102–11.

Google Scholar 

Katoh H, Wang D, Daikoku T, Sun H, Dey SK, Dubois RN. Suppressor cells are essential to promote colitis-associated tumorigenesis. Cancer Cell. 2013;24:631–44. https://doi.org/10.1016/j.ccr.2013.10.009.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han Y, Liu D, Li L. PD-1/PD-L1 pathway: current researches in cancer. Am J Cancer Res. 2020;10:727–42.

CAS  PubMed  PubMed Central  Google Scholar 

Adamczyk M, Krasowska D. PD1 / PD-L1 pathway in psoriasis and psoriatic arthritis: a review. Adv Dermatol Allergol. 2021;38:925–30.