Soria F, Shariat SF, Lerner SP, et al. Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC). World J Urol. 2017;35:379–87.
Petros FG. Epidemiology, clinical presentation, and evaluation of upper-tract urothelial carcinoma. Transl Androl Urol. 2020;9:1794–8.
Article PubMed PubMed Central Google Scholar
Sfakianos JP, Gul Z, Shariat SF, Matin SF, Daneshmand S, Plimack E, Lerner S, Roupret M, Pal S. Genetic differences between bladder and upper urinary tract carcinoma: implications for therapy. Eur Urol Oncol. 2021;4:170–9.
Fujii Y, Sato Y, Suzuki H, et al. Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer Cell. 2021;39:793-809.e8.
Article CAS PubMed PubMed Central Google Scholar
Necchi A, Madison R, Pal SK, et al. Comprehensive genomic profiling of upper-tract and bladder urothelial carcinoma. Eur Urol Focus. 2021;7:1339–46.
CollàRuvolo C, Wenzel M, Nocera L, et al. The effect of race on stage at presentation and survival in upper tract urothelial carcinoma. Urol Oncol: Semin Orig Investig. 2021;39:788.e7-788.e13.
Lonati C, Moschini M, Simeone C, Spiess PE, Necchi A. Lynch syndrome in urological practice: diagnosis, therapeutic strategies, and screening for upper tract urothelial carcinoma. Curr Opin Urol. 2022;32:40–7.
Roberts JL, Ghali F, Aganovic L, Bechis S, Healy K, Rivera-Sanfeliz G, Autorino R, Derweesh I. Diagnosis, management, and follow-up of upper tract urothelial carcinoma: an interdisciplinary collaboration between urology and radiology. Abdom Radiol. 2019;44:3893–905.
Schuettfort VM, Pradere B, Quhal F, et al. Diagnostic challenges and treatment strategies in the management of upper-tract urothelial carcinoma. Türk Üroloji Dergisi/Turk J Urol. 2021;47:S33–44.
Petros FG, Qiao W, Singla N, Clinton TN, Robyak H, Raman JD, Margulis V, Matin SF. Preoperative multiplex nomogram for prediction of high-risk nonorgan-confined upper-tract urothelial carcinoma. Urol Oncol: Semin Orig Investig. 2019;37:292.e1-292.e9.
Yates DR, Hupertan V, Colin P, et al. Cancer-specific survival after radical nephroureterectomy for upper urinary tract urothelial carcinoma: proposal and multi-institutional validation of a post-operative nomogram. Br J Cancer. 2012;106:1083–8.
Article CAS PubMed PubMed Central Google Scholar
Ku JH, Moon KC, Jung JH, Jeong SH, Kwak C, Kim HH. External validation of an online nomogram in patients undergoing radical nephroureterectomy for upper urinary tract urothelial carcinoma. Br J Cancer. 2013;109:1130–6.
Article CAS PubMed Google Scholar
Katims AB, Gaffney C, Firouzi S, et al. Feasibility and tissue concordance of genomic sequencing of urinary cytology in upper tract urothelial carcinoma. Urol Oncol: Semin Orig Investig. 2023;41:433.e19-433.e24.
Evmorfopoulos K, Mitrakas L, Karathanasis A, Zachos I, Tzortzis V, Vlachostergios PJ. Upper tract urothelial carcinoma: a rare malignancy with distinct immuno-genomic features in the era of precision-based therapies. Biomedicines. 2023;11:1775.
Article CAS PubMed PubMed Central Google Scholar
Grahn A, Coleman JA, Eriksson Y, et al. Consultation on UTUC II Stockholm 2022: diagnostic and prognostic methods—what’s around the corner? World J Urol. 2023;41:3405–11.
Article PubMed PubMed Central Google Scholar
Grahn A, Eisfeldt J, Malm C, ForoughiAsl H, Jaremko G, Tham E, Brehmer M. Genomic profile – a possible diagnostic and prognostic marker in upper tract urothelial carcinoma. BJU Int. 2022;130:92–101.
Article CAS PubMed Google Scholar
Yip W, Kim K, Kuo F, et al. Upper tract urothelial carcinoma transcriptome profiling and immune microenvironment characterization. J Clin Oncol. 2022;40:564–564.
Van Allen EM, Mouw KW, Kim P, et al. Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma. Cancer Discov. 2014;4:1140–53.
Article PubMed PubMed Central Google Scholar
Hirotsu Y, Yokoyama H, Amemiya K, Hagimoto T, Hosaka K, Oyama T, Mochizuki H, Omata M. Genomic profiling identified ERCC2 E606Q mutation in helicase domain respond to platinum-based neoadjuvant therapy in urothelial bladder cancer. Front Oncol. 2020. https://doi.org/10.3389/fonc.2020.01643.
Article PubMed PubMed Central Google Scholar
Tang Q, Zuo W, Wan C, Xiong S, Xu C, Yuan C, Sun Q, Zhou L, Li X. Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy. Front Immunol. 2023. https://doi.org/10.3389/fimmu.2022.1097730.
Article PubMed PubMed Central Google Scholar
Chalfin HJ, Glavaris SA, Gorin MA, et al. Circulating tumor cell and circulating tumor DNA assays reveal complementary information for patients with metastatic urothelial cancer. Eur Urol Oncol. 2021;4:310–4.
Green EA, Li R, Albiges L, Choueiri TK, Freedman M, Pal S, Dyrskjøt L, Kamat AM. Clinical utility of cell-free and circulating tumor DNA in kidney and bladder cancer: a critical review of current literature. Eur Urol Oncol. 2021;4:893–903.
Vandekerkhove G, Lavoie J-M, Annala M, et al. Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer. Nat Commun. 2021;12:184.
Article CAS PubMed PubMed Central Google Scholar
Huelster HL, Gould B, Schiftan EA, et al. Novel use of circulating tumor DNA to identify muscle-invasive and non–organ-confined upper tract urothelial carcinoma. Eur Urol. 2024;85:283–92.
Article CAS PubMed Google Scholar
Mu N, Jylhä C, Axelsson T, Sydén F, Brehmer M, Tham E. Patient-specific targeted analysis of circulating tumour DNA in plasma is feasible and may be a potential biomarker in UTUC. World J Urol. 2023;41:3421–7.
Article CAS PubMed PubMed Central Google Scholar
Tamura D, Abe M, Hiraki H, et al. Postoperative recurrence detection using individualized circulating tumor DNA in upper tract urothelial carcinoma. Cancer Sci. 2024;115:529–39.
Article CAS PubMed Google Scholar
Subiela JD, Territo A, Mercadé A, et al. Diagnostic accuracy of ureteroscopic biopsy in predicting stage and grade at final pathology in upper tract urothelial carcinoma: systematic review and meta-analysis. Eur J Surg Oncol. 2020;46:1989–97.
Uhlén M, Karlsson MJ, Hober A, et al. The human secretome. Sci Signal. 2019. https://doi.org/10.1126/scisignal.aaz0274.
Giudice G, Petsalaki E. Proteomics and phosphoproteomics in precision medicine: applications and challenges. Brief Bioinform. 2019;20:767–77.
Article CAS PubMed Google Scholar
Qu Y, Yao Z, Xu N, et al. Plasma proteomic profiling discovers molecular features associated with upper tract urothelial carcinoma. Cell Rep Med. 2023;4:101166.
Article CAS PubMed PubMed Central Google Scholar
Lu C-M, Lin J-J, Huang H-H, Ko Y-C, Hsu J-L, Chen J-C, Din Z-H, Wu Y-J. A panel of tumor markers, calreticulin, annexin A2, and annexin A3 in upper tract urothelial carcinoma identified by proteomic and immunological analysis. BMC Cancer. 2014;14:363.
Article PubMed PubMed Central Google Scholar
Li P, Tao J, Wei D, et al. Serum metabolomic analysis of human upper urinary tract urothelial carcinoma. Tumor Biology. 2015;36:7531–7.
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