Albrecht K, Binder S, Minden K, Poddubnyy D, Regierer AC, Strangfeld A, Callhoff J. Systematisches Review Zur Schätzung Der Prävalenz entzündlich Rheumatischer Erkrankungen in Deutschland [Systematic review to estimate the prevalence of inflammatory rheumatic diseases in Germany. German Version] Z Rheumatol. 2023;82(9):727–38. https://doi.org/10.1007/s00393-022-01305-2. German.

Article  PubMed  PubMed Central  Google Scholar 

van den Berg R, van der Heijde DM. How should we diagnose spondyloarthritis according to the ASAS classification criteria: a guide for practicing physicians. Pol Arch Med Wewn. 2010;120(11):452–7. PMID: 21102381.

Article  PubMed  Google Scholar 

Feldtkeller E, Khan MA, van der Heijde D, van der Linden S, Braun J. Age at disease onset and diagnosis delay in HLA-B27 negative vs. positive patients with ankylosing spondylitis. Rheumatol Int. 2003;23(2):61 – 6. https://doi.org/10.1007/s00296-002-0237-4. Epub 2002 Sep 3. PMID: 12634937.

Senbekov M, Saliev T, Bukeyeva Z, Almabayeva A, Zhanaliyeva M, Aitenova N, Toishibekov Y, Fakhradiyev I. The recent progress and applications of Digital Technologies in Healthcare: a review. Int J Telemed Appl. 2020;2020:8830200. https://doi.org/10.1155/2020/8830200. PMID: 33343657; PMCID: PMC7732404.

Article  PubMed  PubMed Central  Google Scholar 

Zimba O, Kocyigit BF, Korkosz M. Diagnosis, monitoring, and management of axial spondyloarthritis. Rheumatol Int. 2024 May 17. https://doi.org/10.1007/s00296-024-05615-3. Epub ahead of print. PMID: 38758383.

Ortolan A, Webers C, Sepriano A, Falzon L, Baraliakos X, Landewé RB, Ramiro S, van der Heijde D, Nikiphorou E. Efficacy and safety of non-pharmacological and non-biological interventions: a systematic literature review informing the 2022 update of the ASAS/EULAR recommendations for the management of axial spondyloarthritis. Ann Rheum Dis. 2023;82(1):142–52. https://doi.org/10.1136/ard-2022-223297. Epub 2022 Oct 19. PMID: 36261247.

Article  CAS  PubMed  Google Scholar 

Ramiro S, Nikiphorou E, Sepriano A, Ortolan A, Webers C, Baraliakos X, Landewé RBM, Van den Bosch FE, Boteva B, Bremander A, Carron P, Ciurea A, van Gaalen FA, Géher P, Gensler L, Hermann J, de Hooge M, Husakova M, Kiltz U, López-Medina C, Machado PM, Marzo-Ortega H, Molto A, Navarro-Compán V, Nissen MJ, Pimentel-Santos FM, Poddubnyy D, Proft F, Rudwaleit M, Telkman M, Zhao SS, Ziade N, van der Heijde D. ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update. Ann Rheum Dis. 2023;82(1):19–34. https://doi.org/10.1136/ard-2022-223296. Epub 2022 Oct 21. PMID: 36270658.

Article  PubMed  Google Scholar 

Gravaldi LP, Bonetti F, Lezzerini S, De Maio F. Effectiveness of Physiotherapy in patients with Ankylosing spondylitis: a systematic review and Meta-analysis. Healthc (Basel). 2022;10(1):132. https://doi.org/10.3390/healthcare10010132. PMID: 35052296; PMCID: PMC8775656.

Article  Google Scholar 

Zão A, Cantista P. The role of land and aquatic exercise in ankylosing spondylitis: a systematic review. Rheumatol Int. 2017;37(12):1979–1990. https://doi.org/10.1007/s00296-017-3829-8. Epub 2017 Oct 5. PMID: 28983663.

Pécourneau V, Degboé Y, Barnetche T, Cantagrel A, Constantin A, Ruyssen-Witrand A. Effectiveness of Exercise Programs in Ankylosing spondylitis: a Meta-analysis of Randomized controlled trials. Arch Phys Med Rehabil. 2018;99(2):383–e3891. https://doi.org/10.1016/j.apmr.2017.07.015. Epub 2017 Aug 30. PMID: 28860095.

Article  PubMed  Google Scholar 

Pina Gonçalves N, Emília Santos M, Silvério-António M, Donato H, Pimentel-Santos FM, Cruz E. The effects of physical exercise on axial spondyloarthritis - a systematic review. ARP Rheumatol 2023 Aug 27. English. Epub ahead of print. PMID: 37728143.

Boudjani R, Challal S, Semerano L, Sigaux J. Impact of different types of exercise programs on ankylosing spondylitis: a systematic review and meta-analysis. Disabil Rehabil. 2023;45(24):3989–4000. https://doi.org/10.1080/09638288.2022.2140842. Epub 2022 Nov 11. PMID: 36369692.

Hilberdink B, van der Giesen F, Vliet Vlieland T, van Gaalen F, van Weely S. Supervised Group Exercise in Axial Spondyloarthritis: patients’ satisfaction and perspective on evidence-based Enhancements. Arthritis Care Res. 2020;72(6):829–37. PMID:30927518.

Article  Google Scholar 

Strunz PP, Maire ML, Heusinger T, Hammel L, Gernert M, Schwaneck EC, Callhoff J, Portegys J, Schmalzing M, Tony HP, Froehlich M. Apps in Der Rheumatologie: Bedarf es Einer App in Der Therapie Der Axialen Spondyloarthritis? [Apps in rheumatology: is there a need for an app in therapy for axial spondyloarthritis?]. Z Rheumatol. 2023;82(3):256–61. https://doi.org/10.1007/s00393-021-01104-1. German.

Article  PubMed  Google Scholar 

Knitza J, Simon D, Lambrecht A, Raab C, Tascilar K, Hagen M, Kleyer A, Bayat S, Derungs A, Amft O, Schett G, Hueber AJ. Mobile Health usage, preferences, barriers, and eHealth literacy in Rheumatology: Patient Survey Study. JMIR Mhealth Uhealth. 2020;8(8):e19661. https://doi.org/10.2196/19661. PMID: 32678796; PMCID: PMC7450373.

Article  PubMed  PubMed Central  Google Scholar 

Azevedo R, Bernardes M, Fonseca J, Lima A. Smartphone application for rheumatoid arthritis self-management: cross-sectional study revealed the usefulness, willingness to use and patients’ needs. Rheumatol Int. 2015;35(10):1675–85. https://doi.org/10.1007/s00296-015-3270-9. Epub 2015 Apr 24. PMID: 25903352.

Article  PubMed  Google Scholar 

Kwan YH, Ong WJ, Xiong M, Leung YY, Phang JK, Wang CTM, Fong W. Evaluation of mobile apps targeted at patients with Spondyloarthritis for Disease Monitoring: systematic app search. JMIR MHealth UHealth. 2019;7(10):e14753. https://doi.org/10.2196/14753.

Article  PubMed  PubMed Central  Google Scholar 

Song Y, Chen H. Evaluating Chinese Mobile Health Apps for Ankylosing Spondylitis Management: systematic app search. JMIR MHealth UHealth. 2021;9(7):e27234. https://doi.org/10.2196/27234.

Article  PubMed  PubMed Central  Google Scholar 

Abaton URL. https://www.abaton.info/ueber-abaton (23.05.2024).

Rheuma-Auszeit URL. https://www.rheuma-liga.de/infothek/app (17.05.2024).

DiGA-Verzeichnis. des Bundesinstituts für Arzneimitten und Medizinprodukte (DiGA-directory oft he federal institute for drugs and medical devices), URL: https://diga.bfarm.de/de/verzeichnis/00387 (01. April 2024).

Digitale-Versorgungs-Gesetz (DVG, Digital Health Care Law.), URL: https://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl119s2562.pdf#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl119s2562.pdf%27%5D__1716552966964 (24.05.2024).

Weise H, Zenner B, Schmiedchen B, Benning L, Bulitta M, Schmitz D, Weise K. The Effect of an App-Based Home Exercise Program on Self-reported Pain Intensity in Unspecific and Degenerative Back Pain: Pragmatic Open-label Randomized Controlled Trial. J Med Internet Res. 2022;24(10):e41899. https://doi.org/10.2196/41899. Erratum in: J Med Internet Res. 2023;25:e46512. PMID: 36215327; PMCID: PMC9652727.

Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J, Braun J, Chou CT, Collantes-Estevez E, Dougados M, Huang F, Gu J, Khan MA, Kirazli Y, Maksymowych WP, Mielants H, Sørensen IJ, Ozgocmen S, Roussou E, Valle-Oñate R, Weber U, Wei J, Sieper J. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009;68(6):777 – 83. https://doi.org/10.1136/ard.2009.108233. Epub 2009 Mar 17. Erratum in: Ann Rheum Dis. 2019;78(6):e59. https://doi.org/10.1136/ard.2009.108233corr1. PMID: 19297344.

Rudwaleit M, Taylor WJ. Classification criteria for psoriatic arthritis and ankylosing spondylitis/axial spondyloarthritis. Best Pract Res Clin Rheumatol. 2010;24(5):589–604. https://doi.org/10.1016/j.berh.2010.05.007. PMID: 21035082.

Akgul O, Ozgocmen S. Classification criteria for spondyloarthropathies. World J Orthop. 2011;2(12):107–15. https://doi.org/10.5312/wjo.v2.i12.07. PMID: 22474629; PMCID: PMC3302034.

Article  PubMed  PubMed Central  Google Scholar 

Contraindications ViViRA URL. https://www.vivira.com/fileadmin/user_upload/002_vivira_website/0029_downloads/2022/ViViRA-Kontraindikationen-2023.pdf (21.10.2024).

DRKS-ID DRKS00031254, URL. https://drks.de/search/de/trial/DRKS00031254 (21.06.2024).

Garcia KKS, Abrahão AA. Research Development using REDCap Software. Healthc Inf Res. 2021;27(4):341–9. https://doi.org/10.4258/hir.2021.27.4.341. Epub 2021 Oct 31. PMID: 34788915; PMCID: PMC8654330.

Article  Google Scholar 

Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A. Defining spinal mobility in ankylosing spondylitis (AS). The bath AS Metrology Index. J Rheumatol. 1994;21(9):1694–8. PMID: 7799351.

CAS  PubMed  Google Scholar 

Zochling J. Measures of symptoms and disease status in ankylosing spondylitis: Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life Scale (ASQoL), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Global Score (BAS-G), Bath Ankylosing Spondylitis Metrology Index (BASMI), Dougados Functional Index (DFI), and Health Assessment Questionnaire for the Spondylarthropathies (HAQ-S). Arthritis Care Res (Hoboken). 2011;63 Suppl 11:S47-58. https://doi.org/10.1002/acr.20575. PMID: 22588768.

Karcioglu O, Topacoglu H, Dikme O, Dikme O. A systematic review of the pain scales in adults: which to use? Am J Emerg Med. 2018;36(4):707–14. https://doi.org/10.1016/j.ajem.2018.01.008. Epub 2018 Jan 6. PMID: 29321111.

Article  PubMed  Google Scholar 

Freynhagen R, Baron R, Gockel U, Tölle TR. painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin. 2006;22(10):1911-20. https://doi.org/10.1185/030079906X132488. PMID: 17022849.

Yang X, Fan D, Xia Q, Wang M, Zhang X, Li X, Cai G, Wang L, Xin L, Xu S, Pan F. The health-related quality of life of ankylosing spondylitis patients assessed by SF-36: a systematic review and meta-analysis. Qual Life Res. 2016;25(11):2711–23. Epub 2016 Jun 20. PMID: 27324038.

Article  PubMed  Google Scholar 

Datenschutzerklärung ViViRA. (data declaration ViViRA), URL: https://www.vivira.com/fileadmin/user_upload/002_vivira_website/0038_dse/20220624-Datenschutzerklaerung.pdf (11.04.2024).

Kassambara A. 2023. rstatix: Pipe-Friendly Framework for Basic Statistical Tests. R package version 0.7.2, https://CRAN.R-project.org/package=rstatix

Mair P, Wilcox R. Robust statistical methods in R using the WRS2 package. Behav Res Methods. 2020;52(2):464–488. https://doi.org/10.3758/s13428-019-01246-w. PMID: 31152384.

Lenth R. 2024. emmeans: Estimated Marginal Means, aka Least-Squares Means. R package version 1.10.0, https://CRAN.R-project.org/package=emmeans

Venables WN, Ripley BD. (2002) Modern Applied Statistics with S. Fourth Edition. Springer, New York. ISBN 0-387-95457-0.

Solis-Navarro L, Gismero A, Fernández-Jané C, Torres-Castro R, Solá-Madurell M, Bergé C, Pérez LM, Ars J, Martín-Borràs C, Vilaró J, Sitjà-Rabert M. Effectiveness of home-based exercise delivered by digital health in older adults: a systematic review and meta-analysis. Age Ageing. 2022;51(11):afac243. https://doi.org/10.1093/ageing/afac243. PMID: 36346736; PMCID: PMC9642810.

Article  PubMed  PubMed Central  Google Scholar 

Paul L, McDonald MT, McConnachie A, Siebert S, Coulter EH. Online physiotherapy for people with axial spondyloarthritis: quantitative and qualitative data from a cohort study. Rheumatol Int. 2024;44(1):145–56. https://doi.org/10.1007/s00296-023-05456-6. Epub 2023 Sep 21. PMID: 37733042; PMCID: PMC10766789.

Article  CAS  PubMed  Google Scholar 

de Hooge M, Ramonda R, Lorenzin M, Frallonardo P, Punzi L, Ortolan A, Doria A. Work productivity is associated with disease activity and functional ability in Italian patients with early axial spondyloarthritis: an observational study from the SPACE cohort. Arthritis Res Ther. 2016;18(1):265. https://doi.org/10.1186/s13075-016-1162-3. PMID: 27852321; PMCID: PMC5112652.

Article  PubMed  PubMed Central  Google Scholar 

Martinez-Calderon J, Flores-Cortes M, Morales-Asencio JM, Luque-Suarez A, Pain-Related, Fear. Pain Intensity and Function in Individuals with Chronic Musculoskeletal Pain: A Systematic Review and Meta-Analysis. J Pain. 2019;20(12):1394–1415. https://doi.org/10.1016/j.jpain.2019.04.009. Epub 2019 May 4. PMID: 31063874.

Swinnen TW, Westhovens R, Dankaerts W, de Vlam K. Widespread pain in axial spondyloarthritis: clinical importance and gender differences. Arthritis Res Ther. 2018;20(1):156. https://doi.org/10.1186/s13075-018-1626-8. PMID: 30053895; PMCID: PMC6062924.

Article  PubMed  PubMed Central