Cross AL., Viswanath O, Sherman AL. Pregabalin. In StatPearls [Internet]. StatPearls Publishing. 2020.https://www.ncbi.nlm.nih.gov/books/NBK470341/. Accessed 24 Apr 2024.

Lyrica®. Annex I Summary of Product Characteristics. Pfizer. 2020. https://www.ema.europa.eu/en/documents/product-information/lyrica-epar-product-information_en.pdf. Accessed 24 Apr 2024.

Alles SRA, Cain SM, Snutch TP. Pregabalin as a pain therapeutic: beyond calcium channels. Front Cell Neurosci. 2020;14:83. https://doi.org/10.3389/fncel.2020.00083.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Evoy KE, Morrison MD, Saklad SR. Abuse and misuse of pregabalin and gabapentin. Drugs. 2017;77(4):403–26. https://doi.org/10.1007/s40265-017-0700-x.

Article  CAS  PubMed  Google Scholar 

Mathieson S, Lin CC, Underwood M, Eldabe S. Pregabalin and gabapentin for pain. BMJ. 2020;369: m1315. https://doi.org/10.1136/bmj.m1315.

Article  PubMed  Google Scholar 

Chincholkar M. Analgesic mechanisms of gabapentinoids and effects in experimental pain models: a narrative review. Br J Anaesth. 2018;120(6):1315–34. https://doi.org/10.1016/j.bja.2018.02.066.

Article  CAS  PubMed  Google Scholar 

Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain-United States, 2016. JAMA. 2016;315(15):1624–45. https://doi.org/10.1001/jama.2016.1464.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Łuszczki JJ. Dose-response relationship analysis of pregabalin doses and their antinociceptive effects in hot-plate test in mice. Pharmacol Rep. 2010;62(5):942–8. https://doi.org/10.1016/s1734-1140(10)70355-8.

Article  PubMed  Google Scholar 

Shamsi Meymandi M, Keyhanfar F. Relative potency of pregabalin, gabapentin, and morphine in a mouse model of visceral pain. Can J Anaesth. 2013;60(1):44–9. https://doi.org/10.1007/s12630-012-9813-6.

Article  PubMed  Google Scholar 

Tanabe M, Ono K, Honda M, Ono H. Gabapentin and pregabalin ameliorate mechanical hypersensitivity after spinal cord injury in mice. Eur J Pharmacol. 2009;609(1–3):65–8. https://doi.org/10.1016/j.ejphar.2009.03.020.

Article  CAS  PubMed  Google Scholar 

Johansen ME. Gabapentinoid use in the United States 2002 through 2015. JAMA Intern Med. 2018;178(2):292–4. https://doi.org/10.1001/jamainternmed.2017.7856.

Article  PubMed  PubMed Central  Google Scholar 

Goins A, Patel K, Alles SRA. The gabapentinoid drugs and their abuse potential. Pharmacol Ther. 2021;227: 107926. https://doi.org/10.1016/j.pharmthera.2021.107926.

Article  CAS  PubMed  Google Scholar 

Spoendlin J, Blozik E, Graber S, Rauch M, Marxer C, Rüegg S, Meier C, Winterfeld U, Panchaud A. Use of valproate in pregnancy and in women of childbearing age between 2014 and 2018 in Switzerland: a retrospective analysis of Swiss healthcare claims data. Swiss Med Wkly. 2021;151: w20386. https://doi.org/10.4414/smw.2021.20386.

Article  PubMed  Google Scholar 

Blotière PO, Raguideau F, Weill A, Elefant E, Perthus I, Goulet V, Rouget F, Zureik M, Coste J, Dray-Spira R. Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs. Neurology. 2019;93(2):e167–80. https://doi.org/10.1212/wnl.0000000000007696.

Article  PubMed  PubMed Central  Google Scholar 

Etemad L, Mohammad A, Mohammadpour AH, Vahdati Mashhadi N, Moallem SA. Teratogenic effects of pregabalin in mice. Iran J Basic Med Sci. 2013;16(10):1065–70.

PubMed  PubMed Central  Google Scholar 

Singh KP, Gupta K. Teratogenic effects of third-generation antiepileptic drug, pregabalin: an in vivo study. Curr Drug Saf. 2018;13(2):113–21. https://doi.org/10.2174/1574886313666180402145645.

Article  CAS  PubMed  Google Scholar 

Winterfeld U, Merlob P, Baud D, Rousson V, Panchaud A, Rothuizen LE, Bernard N, Vial T, Yates LM, Pistelli A, Ellfolk M, Eleftheriou G, de Vries LC, Jonville-Bera AP, Kadioglu M, Biollaz J, Buclin T. Pregnancy outcome following maternal exposure to pregabalin may call for concern. Neurology. 2016;86(24):2251–7. https://doi.org/10.1212/wnl.0000000000002767.

Article  CAS  PubMed  Google Scholar 

Kim Y, Brodt MD, Tang SY, Silva MJ. MicroCT for scanning and analysis of mouse bones. Methods Mol Biol. 2021;2230:169–98. https://doi.org/10.1007/978-1-0716-1028-2_11.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rovaris K, Queiroz PM, Vasconcelos KF, Corpas LDS, Silveira BMD, Freitas DQ. Segmentation methods for micro CT images: a comparative study using human bone samples. Braz Dent J. 2018;29(2):150–3. https://doi.org/10.1590/0103-6440201801385.

Article  PubMed  Google Scholar 

Free RD, DeRocher K, Stock SR, et al. Characterization of enamel caries lesions in rat molars using synchrotron X-ray microtomography. J Synchrotron Radiat. 2017;24(Pt 5):1056–64. https://doi.org/10.1107/s1600577517008724.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sinibaldi R, Conti A, Sinjari B, et al. Multimodal-3D imaging based on μMRI and μCT techniques bridges the gap with histology in visualization of the bone regeneration process. J Tissue Eng Regen Med. 2018;12(3):750–61. https://doi.org/10.1002/term.2494.

Article  CAS  PubMed  Google Scholar 

Hasanein P, Shakeri S. Pregabalin role in inhibition of morphine analgesic tolerance and physical dependency in rats. Eur J Pharmacol. 2014;742:113–7. https://doi.org/10.1016/j.ejphar.2014.08.030.

Article  CAS  PubMed  Google Scholar 

Alder S, Zbinden G. Methods for the evaluation of physical, neuromuscular, and behavioral development of rats in early postnatal life. Methods Prenatal Toxicol. 1977;1977:175–85.

Google Scholar 

Kaneko H, Hashimoto S, Enokiya Y, Ogiuchi H, Shimono M. Cell proliferation and death of Hertwig’s epithelial root sheath in the rat. Cell Tissue Res. 1999;298(1):95–103. https://doi.org/10.1007/s004419900061.

Article  CAS  PubMed  Google Scholar 

European Medicines Agency. Annex I Summary of Product Characteristics. https://www.ema.europa.eu/en/documents/product-information/pregabalin-sandoz-gmbh-epar-product-information_en.pdf. Accessed 24 Apr 2024.

Kleinman KP, Oken E, Radesky JS, Rich-Edwards JW, Peterson KE, Gillman MW. How should gestational weight gain be assessed? A comparison of existing methods and a novel method, area under the weight gain curve. Int J Epidemiol. 2007;36(6):1275–82. https://doi.org/10.1093/ije/dym156.

Article  PubMed  Google Scholar 

Qi Y, He J. Neurophysiologic profiling of at-risk low and very low birth-weight infants using magnetic resonance imaging. Front Physiol. 2021;12: 638868. https://doi.org/10.3389/fphys.2021.638868.

Article  PubMed  PubMed Central  Google Scholar 

Othman A. Child developmental delays and disorders: speech and language delay. FP Essent. 2021;510:17–21.

PubMed  Google Scholar 

Morse DC, Henck JW, Bailey SA. Developmental toxicity studies with pregabalin in rats: significance of alterations in skull bone morphology. Birth Defects Res B Dev Reprod Toxicol. 2016;107(2):94–107. https://doi.org/10.1002/bdrb.21175.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Margulis AV, Hernandez-Diaz S, McElrath T, et al. Relation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth. PLoS ONE. 2019;14(8): e0214180. https://doi.org/10.1371/journal.pone.0214180.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Veiby G, Daltveit AK, Engelsen BA, Gilhus NE. Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy. J Neurol. 2014;261(3):579–88. https://doi.org/10.1007/s00415-013-7239-x.

Article  CAS  PubMed