Adel Fahmideh M, Scheurer ME (2021) Pediatric brain tumors: descriptive epidemiology, risk factors, and future directions. Cancer Epidemiol Biomarkers Prev 30:813–821. https://doi.org/10.1158/1055-9965.EPI-20-1443

Article  PubMed  Google Scholar 

Ryall S, Tabori U, Hawkins C (2020) Pediatric low-grade glioma in the era of molecular diagnostics. Acta Neuropathol Commun 8:30. https://doi.org/10.1186/s40478-020-00902-z

Article  PubMed  PubMed Central  Google Scholar 

Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neurooncology 23:1231–1251. https://doi.org/10.1093/neuonc/noab106

Article  CAS  Google Scholar 

Guerin JB, Kaufmann TJ, Eckel LJ et al (2023) A radiologist’s guide to the 2021 WHO central nervous system tumor classification: part 2—Newly described and revised tumor types. Radiology 307:e221885. https://doi.org/10.1148/radiol.221885

Article  PubMed  Google Scholar 

Hu W, Guo F, Xu Y et al (2022) Differentiation of neoplastic and Non-neoplastic intracranial enhancement lesions using Three-Dimensional Pseudo-Continuous arterial spin labeling. Front Neurosci 16:812997. https://doi.org/10.3389/fnins.2022.812997

Article  PubMed  PubMed Central  Google Scholar 

Law M, Hamburger M, Johnson G et al (2004) Differentiating surgical from Non-Surgical lesions using perfusion MR imaging and proton MR spectroscopic imaging. Technol Cancer Res Treat 3:557–565. https://doi.org/10.1177/153303460400300605

Article  PubMed  Google Scholar 

Korany GM, El Aziz Sayed SA, Ali NM, Ryad KF (2021) The role of magnetic resonance spectroscopy in differentiation of neoplastic from non-neoplastic pediatric intracerebral brain lesions. J Curr Med Res Pract 6. https://doi.org/10.4103/JCMRP.JCMRP_148_19

Van Zijl PCM, Zhou J, Mori N et al (2003) Mechanism of magnetization transfer during on-resonance water saturation. A new approach to detect mobile proteins, peptides, and lipids. Magn Reson Med 49:440–449. https://doi.org/10.1002/mrm.10398

Article  CAS  PubMed  Google Scholar 

Zhou J, Payen J-F, Wilson DA et al (2003) Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nat Med 9:1085–1090. https://doi.org/10.1038/nm907

Article  CAS  PubMed  Google Scholar 

Jones CK, Schlosser MJ, Van Zijl PCM et al (2006) Amide proton transfer imaging of human brain tumors at 3T. Magn Reson Med 56:585–592. https://doi.org/10.1002/mrm.20989

Article  PubMed  Google Scholar 

Zhang H, Zhou J, Peng Y (2021) Amide proton Transfer–Weighted MR imaging of pediatric central nervous system diseases. Magn Reson Imaging Clin N Am 29:631–641. https://doi.org/10.1016/j.mric.2021.06.012

Article  CAS  PubMed  Google Scholar 

Zhang H, Yong X, Ma X et al (2021) Differentiation of low- and high-grade pediatric gliomas with amide proton transfer imaging: added value beyond quantitative relaxation times. Eur Radiol 31:9110–9119. https://doi.org/10.1007/s00330-021-08039-w

Article  CAS  PubMed  Google Scholar 

Zhang H, Tang X, Lv Y et al (2020) Amide proton Transfer-Weighted (APTw) imaging of intracranial infection in children: initial experience and comparison with Gadolinium-Enhanced T1-Weighted imaging. Biomed Res Int 2020:1–13. https://doi.org/10.1155/2020/6418343

Article  CAS  Google Scholar 

Louis DN, Perry A, Reifenberger G et al (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131:803–820. https://doi.org/10.1007/s00401-016-1545-1

Article  PubMed  Google Scholar 

Zhou J, Zaiss M, Knutsson L et al (2022) Review and consensus recommendations on clinical APT -weighted imaging approaches at 3T: application to brain tumors. Magn Reson Med 88:546–574. https://doi.org/10.1002/mrm.29241

Article  PubMed  PubMed Central  Google Scholar 

Wen Z, Hu S, Huang F et al (2010) MR imaging of high-grade brain tumors using endogenous protein and peptide-based contrast. NeuroImage 51:616–622. https://doi.org/10.1016/j.neuroimage.2010.02.050

Article  PubMed  Google Scholar 

Togao O, Yoshiura T, Keupp J et al (2014) Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades. Neurooncology 16:441–448. https://doi.org/10.1093/neuonc/not158

Article  CAS  Google Scholar 

Unal I (2017) Defining an optimal Cut-Point value in ROC analysis: an alternative approach. Comput Math Methods Med 2017:1–14. https://doi.org/10.1155/2017/3762651

Article  Google Scholar 

Wu B, Warnock G, Zaiss M et al (2016) An overview of CEST MRI for non-MR physicists. EJNMMI Phys 3:19. https://doi.org/10.1186/s40658-016-0155-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nakayama M, Naganawa S, Ouyang M et al (2021) A review of clinical and imaging findings in tumefactive demyelination. Am J Roentgenol 217:186–197. https://doi.org/10.2214/AJR.20.23226

Article  Google Scholar 

Koike H, Morikawa M, Ishimaru H et al (2023) Amide proton transfer–Chemical exchange saturation transfer imaging of intracranial brain tumors and Tumor-Like lesions: our experience and a review. Diagnostics 13:914. https://doi.org/10.3390/diagnostics13050914

Article  CAS  PubMed  PubMed Central  Google Scholar 

Obdeijn IV, Wiegers EC, Alic L et al (2024) Amide proton transfer weighted imaging in pediatric neuro-oncology: initial experience. NMR Biomed 37:e5122. https://doi.org/10.1002/nbm.5122

Article  CAS  PubMed  Google Scholar 

Sotirios B, Demetriou E, Topriceanu CC, Zakrzewska Z (2020) The role of APT imaging in gliomas grading: A systematic review and meta-analysis. Eur J Radiol 133:109353. https://doi.org/10.1016/j.ejrad.2020.109353

Article  PubMed  Google Scholar 

Choi YS, Ahn SS, Lee S-K et al (2017) Amide proton transfer imaging to discriminate between low- and high-grade gliomas: added value to apparent diffusion coefficient and relative cerebral blood volume. Eur Radiol 27:3181–3189. https://doi.org/10.1007/s00330-017-4732-0

Article  PubMed  PubMed Central  Google Scholar 

Sakata A, Fushimi Y, Okada T et al (2017) Diagnostic performance between contrast enhancement, proton MR spectroscopy, and amide proton transfer imaging in patients with brain tumors. Magn Reson Imaging 46:732–739. https://doi.org/10.1002/jmri.25597

Article  Google Scholar 

Jiang S, Eberhart CG, Zhang Y et al (2017) Amide proton transfer-weighted magnetic resonance image-guided stereotactic biopsy in patients with newly diagnosed gliomas. Eur J Cancer 83:9–18. https://doi.org/10.1016/j.ejca.2017.06.009

Article  PubMed  PubMed Central  Google Scholar 

Zhang H, Kang H, Zhao X et al (2016) Amide proton transfer (APT) MR imaging and magnetization transfer (MT) MR imaging of pediatric brain development. Eur Radiol 26:3368–3376. https://doi.org/10.1007/s00330-015-4188-z

Article  PubMed  PubMed Central  Google Scholar 

Tang X, Zhang H, Zhou J et al (2020) Brain development in children with developmental delay using amide proton transfer-weighted imaging and magnetization transfer imaging. Pediatr Invest 4:250–256. https://doi.org/10.1002/ped4.12237

Article  CAS  Google Scholar