Survivorship Navigator: Personalized Survivorship Care Plan Generation using Large Language Models

Abstract

Cancer survivorship care plans (SCPs) are critical tools for guiding long-term follow-up care of cancer survivors. Yet, their widespread adoption remains hindered by the significant clinician burden and the time- and labor-intensive process of SCP creation. Current practices require clinicians to extract and synthesize treatment summaries from complex patient data, apply relevant survivorship guidelines, and generate a care plan with personalized recommendations, making SCP generation time-consuming. In this study, we systematically explore the potential of large language models (LLMs) for automating SCP generation and introduce Survivorship Navigator, a framework designed to streamline SCP creation and enhance integration with clinical systems. We evaluate our approach through automated assessments and a human expert study, demonstrating that Survivorship Navigator outperforms baseline methods, producing SCPs that are more accurate, guideline-compliant, and actionable.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

This study did not receive any funding

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

The study used ONLY openly available human data that were originally located at: https://physionet.org/content/curated-oncology-reports/1.0/ The CORAL dataset is a fine-grained, expert-annotated collection of 40 de-identified breast and pancreatic cancer progress notes.

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

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I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

Data Availability

All data utilized in this study are available at https://physionet.org/content/curated-oncology-reports/1.0/

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