Higashi Y, Noma K, Yoshizumi M, Kihara Y (2009) Endothelial function and oxidative stress in cardiovascular diseases. Circ J 73(3):411–418

Article  CAS  PubMed  Google Scholar 

Horikoshi T, Nakamura T, Yamada R, Ishida K, Takemoto K, Takeuchi T, Ishii Y, Suzuki H, Matsumoto H (2025) Association between carotid plaque progression and persistent endothelial dysfunction in an infarct-related coronary artery in STEMI survivors. Heart Vessels 40:36–46

Article  PubMed  Google Scholar 

Krüger-Genge A, Blocki A, Franke R-P, Jung F (2019) Vascular endothelial cell biology: an update. Int J Mol Sci 20(18):4411

Article  PubMed  PubMed Central  Google Scholar 

Sinoway LI, Hendrickson C, Davidson WR, Prophet S, Zelis R (1989) Characteristics of flow-mediated brachial artery vasodilation in human subjects. Circ Res 64(1):32–42

Article  CAS  PubMed  Google Scholar 

Gori T, Muxel S, Damaske A, Radmacher MC, Fasola F, Schaefer S, Schulz A, Jabs A, Parker JD, Münzel T (2012) Endothelial function assessment: flow-mediated dilation and constriction provide different and complementary information on the presence of coronary artery disease. Eur Heart J 33(3):363–371

Article  PubMed  Google Scholar 

Nemoto T, Minami Y, Yamaoka-Tojo M, Sato T, Muramatsu Y, Kakizaki R, Fujiyoshi K, Hashimoto T, Meguro K, Shimohama T, Tojo T, Ako J (2019) Impaired flow-mediated dilation and severity and vulnerability of culprit plaque in patients with coronary artery disease. Int Heart J 60(3):539–545

Article  CAS  PubMed  Google Scholar 

Careri G, Nerla R, Di Monaco A, Russo G, Stazi A, Villano A, Sestito A, Lanza GA, Crea F (2013) Clinical correlates and prognostic value of flow mediated dilation in patients with non-ST segment elevation acute coronary syndromes. Am J Cardiol 111(1):51–57

Article  PubMed  Google Scholar 

Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM (2000) Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20(5):1262–1275

Article  CAS  PubMed  Google Scholar 

Kondo S, Mizukami T, Kobayashi N, Wakabayashi K, Mori H, Yamamoto MH, Yoshida M, Hashimoto T, Muramatsu Y, Minami Y, Ako J (2023) Diagnosis and prognostic value of the underlying cause of acute coronary syndrome in optical coherence tomography-guided emergency percutaneous coronary intervention. J Am Heart Assoc 12(20):e030412

Article  CAS  PubMed  PubMed Central  Google Scholar 

Crea F, Libby P (2017) Acute coronary syndromes: the way forward from mechanisms to precision treatment. Circulation 136(12):1155–1166

Article  PubMed  PubMed Central  Google Scholar 

Quillard T, Franck G, Mawson T, Folco E, Libby P (2017) Mechanisms of erosion of atherosclerotic plaques. Curr Opin Lipidol 28(5):434–441

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yamamoto E, Yonetsu T, Kakuta T, Soeda T, Saito Y, Yan BP, Kurihara O, Takano M, Niccoli G, Higuma T, Kimura S, Minami Y, Ako J, Adriaenssens T, Boeder NF, Nef HM, Fracassi F, Sugiyama T, Lee H, Crea F, Kimura T, Fujimoto JG, Fuster V, Jang IK (2019) Clinical and laboratory predictors for plaque erosion in patients with acute coronary syndromes. J Am Heart Assoc 8(21):e012322

Article  PubMed  PubMed Central  Google Scholar 

Mori H, Yamamoto MH, Mizukami T, Yoshida M, Shimokado A, Okimoto T, Igarashi Y, Kaneko H (2025) Significant stenosis without thrombus: is it the third most common morphology of acute coronary syndrome? CJC Open 7:641–648

Article  PubMed  PubMed Central  Google Scholar 

Jekell A, Kalani M, Kahan T (2019) The interrelation of endothelial function and microvascular reactivity in different vascular beds, and risk assessment in hypertension: results from the Doxazosin–ramipril study. Heart Vessels 34:484–495

Article  PubMed  Google Scholar 

Niccoli G, Montone RA, Di Vito L, Gramegna M, Refaat H, Scalone G, Leone AM, Trani C, Burzotta F, Porto I, Aurigemma C, Prati F, Crea F (2015) Plaque rupture and intact fibrous cap assessed by optical coherence tomography portend different outcomes in patients with acute coronary syndrome. Eur Heart J 36(22):1377–1384

Article  PubMed  Google Scholar 

Toyota T, Morimoto T, Yamashita Y, Shiomi H, Kato T, Makiyama T, Ikeda Y, Sone K, Suzuki H, Yamamoto T (2019) More- versus less-intensive lipid-lowering therapy: systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes 12(8):e005460

Article  PubMed  Google Scholar 

Seiyama K, Oka A, Miyoshi T, Sudo Y, Takagi W, Ugawa S, Kambara H, Tanaka Y, Hori K, Uwatoko Y, Eguchi M, Matsuzaki T, Imamura K (2025) Impact of an intensive lipid-lowering therapy protocol on achieving target low-density lipoprotein cholesterol levels in patients with acute coronary syndrome. Circ Rep 7(2):131–138

Article  PubMed  PubMed Central  Google Scholar 

Virmani R, Burke AP, Farb A, Kolodgie FD (2006) Pathology of the vulnerable plaque. J Am Coll Cardiol 47(8 Suppl):C13–C18

Article  CAS  PubMed  Google Scholar 

Zhu B, Wu Q, Yan K, Liu G, Jia H, Hu S, Zhang S (2024) The impact of flow-mediated vasodilatation on mechanism and prognosis in patients with acute coronary syndrome: a FMD and OCT study. Rev Cardiovasc Med 25(4):123

Article  PubMed  PubMed Central  Google Scholar 

Shin ES, Ann SH, Singh GB, Lim KH, Yoon HJ, Hur SH, Lee CW, Park DW, Lee SW, Kim YH, Park SJ (2015) OCT–defined morphological characteristics of coronary artery spasm sites in vasospastic angina. JACC Cardiovasc Imaging 8(9):1059–1067

Article  PubMed  Google Scholar 

Dai J, Xing L, Jia H, Zhu Y, Zhang S, Hu S, Ren X, Xu M, Ma L, Fang C, Yin Y, Guo W, Wang C, Yu B, Jiang H (2018) In vivo predictors of plaque erosion in patients with ST-segment elevation myocardial infarction: a clinical, angiographical, and intravascular optical coherence tomography study. Eur Heart J 39(22):2077–2085

Article  PubMed  Google Scholar 

Yahagi K, Davis HR, Arbustini E, Virmani R (2015) Sex differences in coronary artery disease: pathological observations. Atherosclerosis 239(1):260–267

Article  CAS  PubMed  Google Scholar 

Gori T (2018) Endothelial function: a short guide for the interventional cardiologist. Int J Mol Sci 19(12):3838

Article  PubMed  PubMed Central  Google Scholar 

Zhou H, Wang S, Zhao C, He H (2022) Effect of exercise on vascular function in hypertension patients: a meta-analysis of randomized controlled trials. Front Cardiovasc Med 9:1013490

Article  PubMed  PubMed Central  Google Scholar 

Miyamoto M, Kotani K, Ishibashi S, Taniguchi N (2012) The effect of antihypertensive drugs on endothelial function as assessed by flow-mediated vasodilation in hypertensive patients. Int J Vasc Med 2012:1–11

Article  Google Scholar 

Muiesan ML, Salvetti M, Monteduro C, Rizzoni D, Zulli R, Corbellini C, Tufano F, Agabiti-Rosei E (1999) Effect of treatment on flow-dependent vasodilation of the brachial artery in essential hypertension. Hypertension 33(1):575–580

Article  CAS  PubMed  Google Scholar 

Miwa Y, Masai H, Shimizu M (2009) Differential effects of calcium-channel blockers on vascular endothelial function in patients with coronary spastic angina. Circ J 73(4):713–717

Article  CAS  PubMed  Google Scholar 

Zhang N, Chen T, Liu C, Tang B, Nie L, An H, Wang H, Chen L (2013) Inhibition of ubiquitin protein expression and 20S proteasome activity by irbesartan prevents post-infarction ventricular remodeling and decreases TNF-α generation. Biomed Rep 1(6):935–939

Article  CAS  PubMed  PubMed Central  Google Scholar