*Department of Electrical and Biomedical Engineering, University of Vermont College of Engineering and Mathematical Sciences, Burlington, VT;

†Department of Neurological Sciences, University of Vermont Larner College of Medicine, Burlington, VT;

‡Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont Larner College of Medicine, Burlington, VT; and

§Department of Pharmacology, University of Vermont Larner College of Medicine, Burlington, VT.

Correspondence: Marilyn J. Cipolla, PhD, Department of Neurological Sciences, University of Vermont Larner College of Medicine, 149 Beaumont Avenue, HSRF 416A, Burlington, VT 05405 (e-mail: [email protected]).

Supported by the National Institutes of Health, the National Institute of Neurological Disorders and Stroke Grant R21 NS120419-01A1, the Totman Medical Research Trust, and the Cardiovascular Research Institute of Vermont. We also acknowledge support from NIH National Center for Research Resources, award number 1S10RR019246 and 1S10OD025030-01 from the Office of Research Infrastructure Programs to the Microscopy Imaging Center, University of Vermont.

The authors report no conflicts of interest.

All studies were approved by the University of Vermont IACUC.

Raw and analyzed data will be made available upon reasonable request.

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by O. M. O'Brien, S. Tremble, and A. Kropf. The first draft of the manuscript was written by O. M. O'Brien, A. Kropf, and M. J. Cipolla, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.