Agne M, Blank I, Emhardt AJ, Gäbelein CG, Gawlas F, Gillich N, Gonschorek P et al (2014) Modularized CRISPR/dCas9 Effector Toolkit for Target-Specific Gene Regulation. ACS Synth Biol 3(12):986–989

Article  CAS  PubMed  Google Scholar 

Ansari I, Chaturvedi A, Chitkara D, Singh S (2022) CRISPR/Cas Mediated Epigenome Editing for Cancer Therapy. Semin Cancer Biol 83:570–583

Article  CAS  PubMed  Google Scholar 

Bártová Eva (2024) Epigenetic and Gene Therapy in Human and Veterinary Medicine. Environ Epigenetics 10(1):006

Article  Google Scholar 

Baylin SB, Jones PA (2011) A Decade of Exploring the Cancer Epigenome - Biological and Translational Implications. Nat Rev Cancer 11(10):726–734

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhattacharjee G, Gohil N, Siruka D, Khambhati K, Maurya R, Ramakrishna S, Chu D-T, Singh V (2023) CRISPR-dCas9 System for Epigenetic Editing towards Therapeutic Applications. Prog Mol Biol Transl Sci 198:15–24

Article  CAS  PubMed  Google Scholar 

Bhokisham Narendranath, Laudermilch Ethan, Traeger Lindsay L, Bonilla Tonya D, Ruiz-Estevez Mercedes, Becker Jordan R (2023) CRISPR-Cas System: The Current and Emerging Translational Landscape. Cells 12(8):1103. https://doi.org/10.3390/cells12081103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bloomer H, Khirallah J, Li Y, Qiaobing Xu (2022) CRISPR/Cas9 Ribonucleoprotein-Mediated Genome and Epigenome Editing in Mammalian Cells. Adv Drug Deliv Rev 181:114087

Article  CAS  PubMed  Google Scholar 

Bray Freddie, Laversanne Mathieu, Sung Hyuna, Ferlay Jacques, Siegel Rebecca L, Soerjomataram Isabelle, Jemal Ahmedin (2024) Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA A Cancer Journal for Clinicians 74(3):229–63

Article  PubMed  Google Scholar 

Brocken DJW, Tark-Dame M, Dame RT (2018) dCas9: A Versatile Tool for Epigenome Editing. Curr Issues Mol Biol 26:15–32

Article  PubMed  Google Scholar 

Campa CC, Weisbach NR, Santinha AJ, Incarnato D, Platt RJ (2019) Multiplexed Genome Engineering by Cas12a and CRISPR Arrays Encoded on Single Transcripts. Nat Methods 16(9):887–893

Article  CAS  PubMed  Google Scholar 

Castro-Muñoz Leonardo Josué, Ulloa Elenaé Vázquez, Sahlgren Cecilia, Lizano Marcela, De La Cruz-Hernández Erick, Contreras-Paredes Adriana (2023) Modulating Epigenetic Modifications for Cancer Therapy. Oncol Rep 49(3):59. https://doi.org/10.3892/or.2023.8496

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chakrabortty Atonu, Patton Daniel J, Smith Bruce F, Agarwal Payal (2023) miRNAs: Potential as Biomarkers and Therapeutic Targets for Cancer. Genes 14(7):1375. https://doi.org/10.3390/genes14071375

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, Iyer EPR, Lin S et al (2015) Highly Efficient Cas9-Mediated Transcriptional Programming. Nat Methods 12(4):326–328

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Y, Ping Y (2023) Development of CRISPR/Cas Delivery Systems for In Vivo Precision Genome Editing. Acc Chem Res 56(16):2185–2196

Article  CAS  PubMed  Google Scholar 

Chen M, Qi LS (2017) Repurposing CRISPR System for Transcriptional Activation. Adv Exp Med Biol 983:147–157

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Junhao, Pan Yi, Yunhui Lu, Fang Xue, Ma Tianyi, Chen Xi, Wang Yanhong, Fang Xingtang, Zhang Chunlei, Song Chengchuang (2024) The Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation. Genes 15(7):875. https://doi.org/10.3390/genes15070875

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choudhury SR, Cui Yi, Lubecka K, Stefanska B, Irudayaraj J (2016) CRISPR-dCas9 Mediated TET1 Targeting for Selective DNA Demethylation at BRCA1 Promoter. Oncotarget 7(29):46545–46556

Article  PubMed  PubMed Central  Google Scholar 

Cong Le, Ann Ran F, Cox D, Lin S, Barretto R, Habib N, Hsu PD et al (2013) Multiplex Genome Engineering Using CRISPR/Cas Systems. Science 339(6121):819–823

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cui N, Zhang J-T, Li Z, Liu X-Y, Wang C, Huang H, Jia N (2022) Structural Basis for the Non-Self RNA-Activated Protease Activity of the Type III-E CRISPR Nuclease-Protease Craspase. Nat Commun 13(1):7549

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dakal TC, Dhabhai B, Pant A, Moar K, Chaudhary K, Yadav V, Ranga V et al (2024) Oncogenes and Tumor Suppressor Genes: Functions and Roles in Cancers. MedComm 5(6):e582

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dawson MA, Kouzarides T (2012) Cancer Epigenetics: From Mechanism to Therapy. Cell 150(1):12–27

Article  CAS  PubMed  Google Scholar 

Dong Z, Dai L, Zhang Y, Fang C, Shi G, Chen Ye, Li J et al (2020) Hypomethylation of GDNF Family Receptor Alpha 1 Promotes Epithelial-Mesenchymal Transition and Predicts Metastasis of Colorectal Cancer. PLoS Genet 16(11):e1009159

Article  CAS  PubMed  PubMed Central  Google Scholar 

Evmenov Konstantin, Pustogarov Nikolay, Panteleev Dmitri, Safin Artur, Alkalaeva Elena (2024) An Efficient Expression and Purification Protocol for SpCas9 Nuclease and Evaluation of Different Delivery Methods of Ribonucleoprotein. Int J Mol Sci 25(3):1622. https://doi.org/10.3390/ijms25031622

Article  CAS  PubMed  PubMed Central  Google Scholar 

Forrest ME, Khalil AM (2017) Review: Regulation of the Cancer Epigenome by Long Non-Coding RNAs. Cancer Lett 407:106–112

Article  CAS  PubMed  Google Scholar 

Fymat, Alain L. 2017. “Genetics, Epigenetics and Cancer.” Cancer Ther Oncol Int J 4(2) https://doi.org/10.19080/ctoij.2017.04.555634.

Ghafouri-Fard S, Shirvani-Farsani Z, Branicki W, Taheri M (2020) MicroRNA Signature in Renal Cell Carcinoma. Front Oncol 10:596359

Article  PubMed  PubMed Central  Google Scholar 

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N et al (2013) CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell 154(2):442–451

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gonzalez-Salinas F, Rojo R, Martinez-Amador C, Herrera-Gamboa J, Trevino V (2020) Transcriptomic and Cellular Analyses of CRISPR/Cas9-Mediated Edition of FASN Show Inhibition of Aggressive Characteristics in Breast Cancer Cells. Biochem Biophys Res Commun 529(2):321–327

Article  CAS  PubMed  Google Scholar 

Graham TA, Sottoriva A (2017) Measuring Cancer Evolution from the Genome. J Pathol 241(2):183–191

Article  PubMed  Google Scholar 

Grünewald J, Miller BR, Szalay RN, Cabeceiras PK, Woodilla CJ, Eliza JB, Holtz KP, Keith Joung J (2023) Engineered CRISPR Prime Editors with Compact, Untethered Reverse Transcriptases. Nat Biotechnol 41(3):337–343

Article  PubMed