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Genome-wide identification and functional analysis of gene family and the critical role of in response to drought and salt stress in cotton
Genome-wide identification and functional analysis of gene family and the critical role of in response to drought and salt stress in cotton
Cotton is an important natural fiber crop. The Tesmin/TSO1-like CXC (TCX) gene family plays an important role in plant res...
Genome-wide analysis of genes in soybean and the role of in improving salt stress tolerance
Genome-wide analysis of genes in soybean and the role of in improving salt stress tolerance
The histidine phosphotransfer proteins (AHP) plays a pivotal role in the cytokinin signal transduction pathway, which is v...
Multi-omics approaches: transforming the landscape of natural product isolation
Multi-omics approaches: transforming the landscape of natural product isolation
The field of natural product (NPs) discovery has significantly evolved with the advent of multi-omics approaches, encompas...
revealed as a potential diagnostic biomarker for endometriosis based on machine learning and single-cell transcriptomic analysis
revealed as a potential diagnostic biomarker for endometriosis based on machine learning and single-cell transcriptomic analysis
Endometriosis is a prevalent gynecological disease characterized by the ectopic growth of functional endometrial tissue ou...
Comprehensive multi-omics analysis of nucleotide metabolism: elucidating the role and prognostic significance of UCK2 in bladder cancer
Comprehensive multi-omics analysis of nucleotide metabolism: elucidating the role and prognostic significance of UCK2 in bladder cancer
Nucleotide metabolism reprogramming is a hallmark of cancer, yet its systematic investigation remains limited. Here, we pe...
Breaking the palatability trade-off: idealizing resistant starch in rice
Breaking the palatability trade-off: idealizing resistant starch in rice
A recent study by Sang et al. successfully demonstrated the simultaneous editing of SBEIIb to develop rice germplasm with ...
Integrated multi-omics analysis of UL16-binding protein 2 as a prognostic and immunotherapy biomarker for colorectal cancer
Integrated multi-omics analysis of UL16-binding protein 2 as a prognostic and immunotherapy biomarker for colorectal cancer
UL16-binding protein 2 (ULBP2) is an important immune regulatory molecule involved in natural killer cell activation and t...
Exploring the mC epitranscriptome of mRNAs in breast cancer cells through genome engineering and long-read sequencing approaches
Exploring the mC epitranscriptome of mRNAs in breast cancer cells through genome engineering and long-read sequencing approaches
Epitranscriptomics has emerged as a rapidly evolving field that focused on studying post-transcriptional RNA modifications...
LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients
LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients
The volume-regulated anion channel (VRAC) is implicated in remodeling the cytoskeleton. Leucine-rich repeat-containing 8A ...
Thermotolerance for yield and quality in rice: a novel NF-Ys- gene system
Thermotolerance for yield and quality in rice: a novel NF-Ys- gene system
With the increase in global temperatures, heat stress damaged the yield as well as grain quality of many cereal crops. Enh...
Transcriptome analysis reveals no obvious unintended effects in the spleen of CRISPR/Cas9-mediated and double-knockout pigs
Transcriptome analysis reveals no obvious unintended effects in the spleen of CRISPR/Cas9-mediated and double-knockout pigs
Gene editing provides powerful tools for farm animal breeding. Our group previously obtained CD163/pAPN double-knockout (D...
Advancing ornamental plant breeding through genomic technologies: opportunities, challenges, and future directions
Advancing ornamental plant breeding through genomic technologies: opportunities, challenges, and future directions
The ornamental plants constitute an important sector of horticulture industry, which are worth billions of dollars worldwi...
Bioinformatics analysis and expression of the transcription factor in in response to salt stress
Bioinformatics analysis and expression of the transcription factor in in response to salt stress
Salt stress is a significant factor limiting plant growth and can severely reduce crop yields. In addition to causing phys...
LncRNAs in hypoxic microenvironment; insight in their impact in cancer biology
LncRNAs in hypoxic microenvironment; insight in their impact in cancer biology
Hypoxia may facilitate metastasis and tumor advancement in solid tumors. Intratumoral hypoxia may facilitate tumo...
Increased CDKN2A expression correlates with resistance to platinum-based therapy and decreased infiltration of B lymphocytes in colon adenocarcinoma
Increased CDKN2A expression correlates with resistance to platinum-based therapy and decreased infiltration of B lymphocytes in colon adenocarcinoma
Cuproptosis-related gene CDKN2A is involved in the development and progression of various solid tumors. However, the poten...
RNA G-quadruplexes: emerging regulators of gene expression and therapeutic targets
RNA G-quadruplexes: emerging regulators of gene expression and therapeutic targets
RNA G-quadruplexes (rG4s) are non-canonical, four-stranded secondary structures formed by guanine-rich RNA sequences. Thes...
iACP-DPNet: a dual-pooling causal dilated convolutional network for interpretable anticancer peptide identification
iACP-DPNet: a dual-pooling causal dilated convolutional network for interpretable anticancer peptide identification
Anticancer peptides (ACPs) are acknowledged for their potential in cancer therapy, attributed to their safety, low side ef...
Immune-based molecular subtyping of triple-negative breast cancer via SNF-CC and functional validation of key immune-associated genes
Immune-based molecular subtyping of triple-negative breast cancer via SNF-CC and functional validation of key immune-associated genes
Triple-negative breast cancer (TNBC) presents significant therapeutic challenges due to its aggressive nature and lack of ...
Milletomics: a metabolomics centered integrated omics approach toward genetic progression
Milletomics: a metabolomics centered integrated omics approach toward genetic progression
Producing alternative staple foods like millet will be essential to feeding ten billion people by 2050. The increased dema...
Revolutionizing soybean genomics: How CRISPR and advanced sequencing are unlocking new potential
Revolutionizing soybean genomics: How CRISPR and advanced sequencing are unlocking new potential
Soybean Glycine max L., paleopolyploid genome, poses challenges to its genetic improvement. However, the development of re...
Genomic profiling of pan-drug resistant proteus mirabilis Isolates reveals antimicrobial resistance and virulence gene landscape
Genomic profiling of pan-drug resistant proteus mirabilis Isolates reveals antimicrobial resistance and virulence gene landscape
Proteus mirabilis is a gram-negative pathogen that caused significant opportunistic infections. In this study we aimed to ...
Microproteins unveiling new dimensions in cancer
Microproteins unveiling new dimensions in cancer
In the complex landscape of cancer biology, the discovery of microproteins has triggered a paradigm shift, thereby, challe...
Integrative analyses of long and short-read RNA sequencing reveal the spliced isoform regulatory network of seedling growth dynamics in upland cotton
Integrative analyses of long and short-read RNA sequencing reveal the spliced isoform regulatory network of seedling growth dynamics in upland cotton
The polyploid genome of cotton has significantly increased the transcript complexity. Recent advances in full-length trans...
Biotechnological frontiers in harnessing allelopathy for sustainable crop production
Biotechnological frontiers in harnessing allelopathy for sustainable crop production
Allelopathy, the phenomenon in which plants release biochemical compounds that influence the growth and development of nei...
AC092100.1 promotes angiogenesis in pre-eclampsia through YTHDC2/VEGFA signaling
AC092100.1 promotes angiogenesis in pre-eclampsia through YTHDC2/VEGFA signaling
Aberrant long non-coding RNA (lncRNA) expression has been shown to be involved in the pathological process of pre-eclampsi...
Long non-coding RNA MAGEA4-AS1 binding to p53 enhances MK2 signaling pathway and promotes the proliferation and metastasis of oral squamous cell carcinoma
Long non-coding RNA MAGEA4-AS1 binding to p53 enhances MK2 signaling pathway and promotes the proliferation and metastasis of oral squamous cell carcinoma
Long non-coding RNAs (lncRNAs) regulate the occurrence, development and progression of oral squamous cell carcinoma (OSCC)...
Exploring the transcription start sites and other genomic features facilitates the accurate identification and annotation of small RNAs across multiple stress conditions in Mycobacterium tuberculosis
Exploring the transcription start sites and other genomic features facilitates the accurate identification and annotation of small RNAs across multiple stress conditions in Mycobacterium tuberculosis
Mycobacterium tuberculosis (MTB) is a pathogen that is known for its ability to persist in harsh environments and cause ch...
LncRNA XIST/miR-455-3p/HOXC4 axis promotes breast cancer development by activating TGF-β/SMAD signaling pathway
LncRNA XIST/miR-455-3p/HOXC4 axis promotes breast cancer development by activating TGF-β/SMAD signaling pathway
Breast cancer is the second primary cause of cancer death among women. Long non-coding RNA (lncRNA) X-inactive specific tr...
Tet1-mediated activation of the Ampk signaling by Trpv1 DNA hydroxymethylation exerts neuroprotective effects in a rat model of Parkinson’s disease
Tet1-mediated activation of the Ampk signaling by Trpv1 DNA hydroxymethylation exerts neuroprotective effects in a rat model of Parkinson’s disease
Epigenetic regulation plays a role in Parkinson’s disease (PD), and ten-eleven translocation methylcytosine dioxygen...
C-FOS inhibition promotes pancreatic cancer cell ferroptosis by transcriptionally regulating the expression of SLC7A11
C-FOS inhibition promotes pancreatic cancer cell ferroptosis by transcriptionally regulating the expression of SLC7A11
Cellular proto-oncogene C-Fos forms the AP-1 transcription factor by dimerizing with proto-oncogene c-Jun; this factor upr...
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