Ahmed F, Ijaz B, Ahmad Z, Farooq N, Sarwar MB, Husnain T (2020) Modification of miRNA expression through plant extracts and compounds against breast cancer: mechanism and translational significance. Phytomedicine 68:153168
Article PubMed CAS Google Scholar
Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 575(7784):688–692
Article PubMed PubMed Central CAS Google Scholar
Chen B, Sang Y, Song X, Zhang D, Wang L, Zhao W, Liang Y, Zhang N, Yang Q (2021) Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28. Theranostics 11(8):3932–3947
Article PubMed PubMed Central CAS Google Scholar
Deepak KGK, Vempati R, Nagaraju GP, Dasari VR, Nagini S, Rao DN, Malla RR (2020) Tumor microenvironment: challenges and opportunities in targeting metastasis of triple negative breast cancer. Pharmacol Res 153:104683
Article PubMed CAS Google Scholar
Ding Y, Chen X, Liu C, Ge W, Wang Q, Hao X, Wang M, Chen Y, Zhang Q (2021) Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells. J Hematol Oncol 14(1):19
Article PubMed PubMed Central CAS Google Scholar
Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M (2017) ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol 13(1):91–98
Article PubMed CAS Google Scholar
Dou D, Ren X, Han M, Xu X, Ge X, Gu Y, Wang X (2020) Cancer-associated fibroblasts-derived exosomes suppress immune cell function in breast cancer via the miR-92/PD-L1 pathway. Front Immunol 11:2026
Article PubMed PubMed Central CAS Google Scholar
Fernández-Nogueira P, Fuster G, Gutierrez-Uzquiza Á, Gascón P, Carbó N, Bragado P (2021) Cancer-associated fibroblasts in breast cancer treatment response and metastasis. Cancers (Basel) 13(13):3146
Hardy RI, Bove KE, James FW, Kaplan S, Goldman L (1987) A histologic study of laser-induced transmyocardial channels. Lasers Surg Med 6(6):563–573
Article PubMed CAS Google Scholar
Hou Y, Cai S, Yu S, Lin H (2021) Metformin induces ferroptosis by targeting miR-324-3p/GPX4 axis in breast cancer. Acta Biochim Biophys Sin (Shanghai) 53(3):333–341
Article PubMed CAS Google Scholar
Houthuijzen JM, Jonkers J (2018) Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment. Cancer Metastasis Rev 37(4):577–597
Article PubMed CAS Google Scholar
Li I, Nabet BY (2019) Exosomes in the tumor microenvironment as mediators of cancer therapy resistance. Mol Cancer 18(1):32
Article PubMed PubMed Central Google Scholar
Li Z, Chen L, Chen C, Zhou Y, Hu D, Yang J, Chen Y, Zhuo W, Mao M, Zhang X, Xu L, Wang L, Zhou J (2020) Targeting ferroptosis in breast cancer. Biomark Res 8(1):58
Article PubMed PubMed Central Google Scholar
Li Z, Wu X, Wang W, Gai C, Zhang W, Li W, Ding D (2021) Fe(II) and tannic acid-cloaked MOF as carrier of artemisinin for supply of ferrous ions to enhance treatment of triple-negative breast cancer. Nanoscale Res Lett 16(1):37
Article PubMed PubMed Central CAS Google Scholar
Li K, Lin C, Li M, Xu K, He Y, Mao Y, Lu L, Geng W, Li X, Luo Z, Cai K (2022) Multienzyme-like reactivity cooperatively impairs glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways in triple-negative breast cancer for sensitized ferroptosis therapy. ACS Nano 16(2):2381–2398
Article PubMed CAS Google Scholar
Lou W, Liu J, Ding B, Jin L, Xu L, Li X, Chen J, Fan W (2019) Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer. Aging (Albany NY) 11(9):2628–2652
Article PubMed CAS Google Scholar
Lu Q, Yang L, Xiao JJ, Liu Q, Ni L, Hu JW, Yu H, Wu X, Zhang BF (2023) Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway. Free Radic Biol Med 195:89–102
Article PubMed CAS Google Scholar
Nascimento C, Ferreira F (2021) Tumor microenvironment of human breast cancer, and feline mammary carcinoma as a potential study model. Biochim Biophys Acta Rev Cancer 1876(1):188587
Article PubMed CAS Google Scholar
Niu B, Liao K, Zhou Y, Wen T, Quan G, Pan X, Wu C (2021) Application of glutathione depletion in cancer therapy: enhanced ROS-based therapy, ferroptosis, and chemotherapy. Biomaterials 277:121110
Article PubMed CAS Google Scholar
Pegtel DM, Gould SJ (2019) Exosomes. Annu Rev Biochem 88:487–514
Article PubMed CAS Google Scholar
Pelon F, Bourachot B, Kieffer Y, Magagna I, Mermet-Meillon F, Bonnet I, Costa A, Givel AM, Attieh Y, Barbazan J, Bonneau C, Fuhrmann L, Descroix S, Vignjevic D, Silberzan P, Parrini MC, Vincent-Salomon A, Mechta-Grigoriou F (2020) Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms. Nat Commun 11(1):404
Article PubMed PubMed Central CAS Google Scholar
Qi R, Bai Y, Li K, Liu N, Xu Y, Dal E, Wang Y, Lin R, Wang H, Liu Z, Li X, Wang X, Shi B (2023) Cancer-associated fibroblasts suppress ferroptosis and induce gemcitabine resistance in pancreatic cancer cells by secreting exosome-derived ACSL4-targeting miRNAs. Drug Resist Updat 68:100960
Article PubMed CAS Google Scholar
Ren L, Chen H, Song J, Chen X, Lin C, Zhang X, Hou N, Pan J, Zhou Z, Wang L, Huang D, Yang J, Liang Y, Li J, Huang H, Jiang L (2019) MiR-454-3p-mediated Wnt/β-catenin signaling antagonists suppression promotes breast cancer metastasis. Theranostics 9(2):449–465
Article PubMed PubMed Central CAS Google Scholar
Sha R, Xu Y, Yuan C, Sheng X, Wu Z, Peng J, Wang Y, Lin Y, Zhou L, Xu S, Zhang J, Yin W, Lu J (2021) Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy. EBioMedicine 71:103560
Article PubMed PubMed Central CAS Google Scholar
Sun Z, Shi K, Yang S, Liu J, Zhou Q, Wang G, Song J, Li Z, Zhang Z, Yuan W (2018) Effect of exosomal miRNA on cancer biology and clinical applications. Mol Cancer 17(1):147
Article PubMed PubMed Central Google Scholar
Tang W, Xu F, Zhao M, Zhang S (2021) Ferroptosis regulators, especially SQLE, play an important role in prognosis, progression and immune environment of breast cancer. BMC Cancer 21(1):1160
Article PubMed PubMed Central CAS Google Scholar
Wang H, Wei H, Wang J, Li L, Chen A, Li Z (2020) MicroRNA-181d-5p-containing exosomes derived from CAFs promote EMT by regulating CDX2/HOXA5 in breast cancer. Mol Ther Nucleic Acids 19:654–667
Article PubMed CAS Google Scholar
Wang D, Wei G, Ma J, Cheng S, Jia L, Song X, Zhang M, Ju M, Wang L, Zhao L, Xin S (2021b) Identification of the prognostic value of ferroptosis-related gene signature in breast cancer patients. BMC Cancer 21(1):645
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