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SCI Abstract
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Current status and trend of global research on the pharmacological effects of emodin family: bibliometric study and visual analysis
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Coptisine inhibits esophageal carcinoma growth by modulating pyroptosis via inhibition of HGF/c-Met signaling
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Comparative effects of dexpanthenol and thymoquinone on colistin-induced neurotoxicity in rats
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Humic acid from vermicompost effectively regulates the redox status and mitigates the progression of experimental periodontitis
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Marine-derived bioactive compounds for neuropathic pain: pharmacology and therapeutic potential
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Tocilizumab alleviated lipopolysaccharide-induced acute lung injury by improving PI3K/AKT pathway
Acute lung injury (ALI) is a severe inflammatory condition of the respiratory system, associated with high morbidity and m...
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Sexual dysfunctions associated with antipsychotic drug intake: a retrospective analysis of the FDA adverse events reporting system (FAERS)
Sexual dysfunctions (SD) are common and debilitating side effects of antipsychotics. The current study analyzes the occurr...
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Exploring the impact of cuproptosis-related genes on immune infiltration in rheumatoid arthritis
Immune infiltration plays a significant role in the pathogenesis of rheumatoid arthritis (RA). Cuproptosis, a newly charac...
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MiRNAs: main players of cancer drug resistance target ABC transporters
Chemotherapy remains the cornerstone of cancer treatment; however, its efficacy is frequently compromised by the developme...
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Morin, as a natural flavonoid, provides promising influences against cardiovascular diseases
The present investigation evaluated the potential impacts of morin, a natural flavonoid, against cardiovascular disorders....
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MircoRNAs predict and modulate responses to chemotherapy in leukemic patients
Leukemia covers a broad category of cancer malignancies that specifically affect bone marrow and blood cells. While differ...
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Icariin mediates autophagy and apoptosis of hepatocellular carcinoma cells induced by the β-catenin signaling pathway through lncRNA LOXL1-AS1
To investigate the effect of icariin (ICA) on hepatocellular carcinoma (HCC) and its autophagy/apoptosis mechanism in HCC....
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Neurotensin receptor agonist PD149163 modulates LPS-induced enterocyte apoptosis by downregulating TNFR pathway and executioner caspase 3 in endotoxemic mice: insights from in vivo and in silico study
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An update on selective estrogen receptor modulator: repurposing and formulations
The selective estrogen receptor modulator (SERM) raloxifene hydrochloride (RLH) is used extensively in the management and ...
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Targeting ferroptosis: the role of non-coding RNAs in hepatocellular carcinoma progression and therapy
One of the most common tumors is hepatocellular carcinoma (HCC), and the prognosis for late-stage HCC is still not good. I...
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Doxorubicin treatment has a biphasic effect over time on dopamine release and impulsive behavior in Wistar rats
Doxorubicin (Dox) is a chemotherapy agent commonly used to treat multiple types of cancers and is associated with cognitiv...
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Network pharmacology-based strategy to reveal the mechanism of pinocembrin against ovarian cancer
Ovarian cancer stands as the foremost cause of mortality among gynaecological diseases globally, characterized by high mor...
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Immune cell traits and causal relationships with cholecystitis: a mendelian randomization analysis
Cholecystitis, characterized by inflammation of the gallbladder, is intricately linked to immune cells and the cytokines t...
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An updated landscape on nanopharmaceutical delivery for mitigation of colon cancer
Globally, colorectal cancer (CRC) continues to rank among the leading causes of cancer-related death. Systemic toxicity, m...
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A systematic review of the traditional uses, chemistry, and curative aptitude of echinacoside—a phenylethanoid glycoside
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Self-nanoemulsifying drug delivery system for nebulization: fabrication and evaluation for systemic delivery of atorvastatin
The study undertakes the development of an atorvastatin-loaded self-nanoemulsifying drug delivery system (SNEDDS) to impro...
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The molecular mechanism of berberine affecting psoriasis skin inflammation by regulating keratinocyte pyroptosis via the p38 MAPK/NF-κB pathway
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VSIG-3/IGSF11 silencing in A2058 melanoma cells simultaneously suppresses melanoma progression and induces anti-tumoral cytokine profile in human T cells: In silico and in vitro study
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Protective effect of aspirin and gentisic acid, a plant-derived phenolic acid, on acrylamide-induced neurotoxicity by inhibiting apoptosis and autophagy
Acrylamide (ACR) is a toxic agent for humans and animals. Gentisic acid, an aspirin metabolite, has anti...
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Oral toxicity assessment and the mitigation of lung carcinogenesis by phytol and α-bisabolol combination treatment in swiss albino mice: insights into redox enzyme modulation and caspase-dependent cell death mechanisms
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Pre-clinical study of IR808 dye for cervical cancer in vitro and in vivo imaging
There is an urgent need for improved methods for early screening and rapid diagnosis of cervical cancer since current conv...
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Cancer-associated fibroblast-secreted exosomal miR-454-3p inhibits lipid metabolism and ferroptosis in breast cancer by targeting ACSL4
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A single-dose, randomized, crossover bioequivalence study of levamlodipine besilate tablets in healthy subjects
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