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Resistance to platinum-based cancer drugs: a special focus on epigenetic mechanisms
Chemoresistance is a significant clinical challenge, limiting the drug response in cancer. Several mechanisms associated w...
Tabula Rasa HealthCare company profile: involvement on pharmacogenomic and personalized medicine research
A Matos, P Dow, JM Bingham, V Michaud, CH Knowlton and J Turgeon are employees and shareholders of TRHC. LJ Lesko is Chair...
Is there a benefit for CYP2C19 genotype-guided antiplatelet treatment in elderly acute coronary syndrome patients?
JM ten Berg reports grants from the Netherlands Organization for Health Research and Development, a Dutch government insti...
The role of SLCO1B1 genotyping in lowering cardiovascular risk
https://orcid.org/0000-0001-6113-5564Section of General Internal Medicine, Veterans Affairs Boston Healthcare System, Bost...
Resolving discordant CYP2D6 genotyping results in Thai subjects: platform limitations and novel haplotypes
Aim: Several CYP2D6 Luminex xTAG genotype calls were identified as inconsistent or suspicious among Thai subjects and furt...
Efficacy and safety of opioid therapy guided by pharmacogenetics: a systematic review
Aim: To perform a systematic review to determine the efficacy/safety of PGx-guided opioid therapy for chronic/postoperativ...
Inaugural Pharmacogenomics Access and Reimbursement Symposium
The Pharmacogenomics Access & Reimbursement Symposium, a landmark event presented by the Golden Helix Foundation and t...
Pharmacogenomics education, research and clinical implementation in the state of Minnesota
Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increas...
Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes
Aim: Numerous drugs are being widely prescribed for COVID-19 treatment without any direct evidence for the drug safety/eff...
KRAS-targeted therapies in advanced solid cancers: drug the undruggable?
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial intere...