SCI Abstract

search
+
Psychotropic polypharmacy impairs walking independence in post-stroke patients
Psychotropic polypharmacy impairs walking independence in post-stroke patients
Psychotropic drugs are associated with adverse outcomes in older adults. However, evidence on the effect of psychotropic u...
Effect of dapagliflozin on malignant ventricular arrhythmias in elderly after acute myocardial infarction: a propensity score-matched cohort study
Effect of dapagliflozin on malignant ventricular arrhythmias in elderly after acute myocardial infarction: a propensity score-matched cohort study
This study aims to evaluate the effect of dapagliflozin (DAPA) on malignant ventricular arrhythmias (MVA) after acute myoc...
Effects of oral antidiabetic agents on the renin–angiotensin–aldosterone system
Effects of oral antidiabetic agents on the renin–angiotensin–aldosterone system
The renin-angiotensin-aldosterone system (RAAS) is a vital endocrine system that plays a crucial role in maintaining homeo...
Efficacy and safety of pembrolizumab in the treatment of advanced hepatocellular carcinoma: a systematic review and meta-analysis
Efficacy and safety of pembrolizumab in the treatment of advanced hepatocellular carcinoma: a systematic review and meta-analysis
The efficacy and safety of pembrolizumab in treating advanced hepatocellular carcinoma (HCC) are inconsistent across studi...
A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker
A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker
In advanced cancer patients the CYP3A4-mediated clearance of drugs is dependent on the severity of inflammation. In a stud...
Efficacy of cyclophosphamide for skin fibrosis in systemic sclerosis: a systematic review and single-arm meta-analysis
Efficacy of cyclophosphamide for skin fibrosis in systemic sclerosis: a systematic review and single-arm meta-analysis
Systemic sclerosis (SSc) is a chronic connective tissue disorder characterized by skin thickening with vascular and viscer...
Drug-related falls: proportion and impact of hospitalizations in geriatric departments on the prescription of fall-risk increasing drugs (FRIDs)
Drug-related falls: proportion and impact of hospitalizations in geriatric departments on the prescription of fall-risk increasing drugs (FRIDs)
The incidence of drug-related admissions in France was 8.5% in 2018, with falls being the 5 th cause of DRA. The scr...
Correction to: Effectiveness of Macrolides as Add-On Therapy to Beta-Lactams in Community-Acquired Pneumonia: A Meta-Analysis of Randomized Controlled Trials
Correction to: Effectiveness of Macrolides as Add-On Therapy to Beta-Lactams in Community-Acquired Pneumonia: A Meta-Analysis of Randomized Controlled Trials
Correction to: European Journal of Clinical Pharmacology (2025) 81:83–91After the pub...
Tranexamic acid-induced anaphylaxis: a systematic review
Tranexamic acid-induced anaphylaxis: a systematic review
Tranexamic acid (TXA) is a synthetic antifibrinolytic agent widely used in a diverse range of hemorrhagic scenarios. Despi...
Pharmacogenomics-guided treatment versus conventional treatment in patients with Schizophrenia: Evaluation of medication adherence and switching rate
Pharmacogenomics-guided treatment versus conventional treatment in patients with Schizophrenia: Evaluation of medication adherence and switching rate
The main objective of this study was to systematically evaluate the effectiveness of pharmacogenomics-guided treatment (PG...
Disproportionality analysis of serotonin syndrome associated with selective serotonin reuptake inhibitors: a pharmacovigilance analysis
Disproportionality analysis of serotonin syndrome associated with selective serotonin reuptake inhibitors: a pharmacovigilance analysis
The incidence and risk of serotonin syndrome associated with selective serotonin reuptake inhibitors (SSRIs) have increase...
Signal detection between 5-alpha reductase inhibitors and the risk of suicidality and depression: an international pharmacovigilance analysis
Signal detection between 5-alpha reductase inhibitors and the risk of suicidality and depression: an international pharmacovigilance analysis
This study aims to investigate the signal detection between the use of finasteride and dutasteride and the occurr...
Global burden of vaccine-associated Raynaud’s phenomenon, 1968–2024: A comprehensive analysis of the pharmacovigilance database
Global burden of vaccine-associated Raynaud’s phenomenon, 1968–2024: A comprehensive analysis of the pharmacovigilance database
Reports of Raynaud's phenomenon following vaccination have been steadily increasing; however, research on vaccine-asso...
Comparative efficacy and adverse effects of β3-agonists and antimuscarinics in overactive bladder: a network and component network meta-analysis
Comparative efficacy and adverse effects of β3-agonists and antimuscarinics in overactive bladder: a network and component network meta-analysis
To assess and compare the efficacy and adverse effects of β3-adrenergic receptor agonists (vibegron and mirabegron), ...
Literature-based case analysis of serious adverse drug events associated with edoxaban
Literature-based case analysis of serious adverse drug events associated with edoxaban
Edoxaban, a direct oral factor Xa inhibitor, is widely used for stroke prevention in non-valvular atrial fibrillation and ...
Inpatient referrals to a specialist falls and syncope service: prevalence of STOPPFall FRIDs and review of deprescribing patterns
Inpatient referrals to a specialist falls and syncope service: prevalence of STOPPFall FRIDs and review of deprescribing patterns
Falls are the commonest cause of accidental death in older people and the most frequent reason for their presentation to h...
Association between sodium-glucose cotransporter-2 inhibitor and adverse events in patients with moderate to severe chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Association between sodium-glucose cotransporter-2 inhibitor and adverse events in patients with moderate to severe chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Although there is concern about the association of sodium-glucose cotransporter-2 inhibitor (SGLT2i) use with musculoskele...
Evaluating the safety and effectiveness of tolvaptan in patients with heart failure and renal impairment: a systematic review and meta-analysis
Evaluating the safety and effectiveness of tolvaptan in patients with heart failure and renal impairment: a systematic review and meta-analysis
Patients with heart failure and concomitant renal impairment are often prescribed loop diuretics, such as furosemide, as t...
Effects of drugs on the oxygen dissociation curve—a scoping review
Effects of drugs on the oxygen dissociation curve—a scoping review
The shape and position of the hemoglobin-oxygen dissociation curve (ODC) is of critical importance in medicine, as it dete...
The impact of age and renal function on the pharmacokinetics and protein binding characteristics of fludarabine in paediatric and adult patients undergoing allogeneic haematopoietic stem cell transplantation conditioning
The impact of age and renal function on the pharmacokinetics and protein binding characteristics of fludarabine in paediatric and adult patients undergoing allogeneic haematopoietic stem cell transplantation conditioning
To evaluate the population pharmacokinetics of unbound F-Ara-A (the circulating metabolite of fludarabine) in 211 patients...
Sodium-glucose cotransporter 2 inhibitors and renal cancer in the US FDA adverse event reporting system
Sodium-glucose cotransporter 2 inhibitors and renal cancer in the US FDA adverse event reporting system
Recent evidence suggests an association between sodium-glucose cotransporter 2 (SGLT2) inhibitors and a higher risk of ren...
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”
Cite this articleChung, PY., Liao, KF. & Lai, SW. Comment on “Use of statins and risks of ovarian, uterine, and cervic...
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis
With the widespread use of CDK4/6 inhibitors, the number of discontinuations and reductions due to adverse events is incre...
The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review
The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review
The present study aimed to systematically collect and synthesize available cost-effectiveness studies of semaglutide in pa...
Efficacy of tacrolimus versus cyclosporine after lung transplantation: an updated systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials
Efficacy of tacrolimus versus cyclosporine after lung transplantation: an updated systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials
Little data supports using tacrolimus versus cyclosporin for immunosuppression concerning acute rejection and bronchioliti...
Preventive effects of first-generation antihistamine on emergence agitation or delirium: a systematic review
Preventive effects of first-generation antihistamine on emergence agitation or delirium: a systematic review
The effects of first-generation antihistamines in preventing postoperative emergence agitation or delirium are unclear. De...
Evaluation of the predictive performance of an online voriconazole dose calculator in children
Evaluation of the predictive performance of an online voriconazole dose calculator in children
The dosing of voriconazole is challenging in pediatrics. One approach to improve the dosing is through the use of Bayesian...
A critical review on approaches to generate and validate virtual population for physiologically based pharmacokinetic models: Methodologies, case studies and way forward
A critical review on approaches to generate and validate virtual population for physiologically based pharmacokinetic models: Methodologies, case studies and way forward
In silico modeling and simulation techniques such as physiologically based pharmacokinetic (PBPK) and physiologically base...
Pharmacokinetics-pharmacodynamics of first-line antitubercular drugs: a comparative study in tuberculosis patients with and without concomitant diabetes mellitus
Pharmacokinetics-pharmacodynamics of first-line antitubercular drugs: a comparative study in tuberculosis patients with and without concomitant diabetes mellitus
To observe the variability in the plasma concentrations and pharmacokinetic-pharmacodynamic (PK-PD) profiles of first-line...
Efficacy and safety of ticagrelor monotherapy following a brief DAPT vs. prolonged 12-month DAPT in ACS patients post-PCI: a meta-analysis of RCTs
Efficacy and safety of ticagrelor monotherapy following a brief DAPT vs. prolonged 12-month DAPT in ACS patients post-PCI: a meta-analysis of RCTs
As per current guidelines, acute coronary syndrome (ACS) patients who undergo percutaneous coronary intervention (PCI) sho...
Load More
format_indent_increase