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CD27 as a Diagnostic Biomarker and Its Role in Immune Heterogeneity and Predicting Clinical Drug Responses in Hashimoto’s Thyroiditis
CD27 as a Diagnostic Biomarker and Its Role in Immune Heterogeneity and Predicting Clinical Drug Responses in Hashimoto’s Thyroiditis
To identify key genes & potential molecular mechanisms associated with HT to provide new insights for the development ...
Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidemia
Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidemia
Role of SLCO1B1 gene polymorphisms and blood lipid levels before and after atorvastatin treatment among Chinese Han adults...
The Association of PLA2G7 Gene Polymorphisms with Serum Lp-PLA2 Activity and Lipid Profile in Han Chinese Patients with Coronary Heart Disease
The Association of PLA2G7 Gene Polymorphisms with Serum Lp-PLA2 Activity and Lipid Profile in Han Chinese Patients with Coronary Heart Disease
Investigating the distribution patterns of PLA2G7 gene variants in Han Chinese patients with coronary heart disease. Read ...
The Genetic and Molecular Drivers of Multiple Myeloma: Current Insights, Clinical Implications, and the Path Forward
The Genetic and Molecular Drivers of Multiple Myeloma: Current Insights, Clinical Implications, and the Path Forward
We report key controversies and challenges in defining the genetic drivers of Multiple Myeloma, & examine their implic...
PEAR1, PON1, CYP2C19, CYP1A2 and F2R Polymorphisms are Associated with MACE in Clopidogrel-Treated Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
PEAR1, PON1, CYP2C19, CYP1A2 and F2R Polymorphisms are Associated with MACE in Clopidogrel-Treated Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
PEAR1, PON1, CYP2C19, CYP1A2 and F2R Polymorphisms are Associated with MACE in Clopidogrel-Treated Patients with Acute Cor...
Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder
Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder
Role of Bacterial Lipopolysaccharide--associated genes in the immune responses of individuals with Autism Spectrum Disorder
Pharmacogenomics Tools for Precision Public Health and Lessons for Low- and Middle-Income Countries: A Scoping Review
Pharmacogenomics Tools for Precision Public Health and Lessons for Low- and Middle-Income Countries: A Scoping Review
The trend shows a scarce development of technological tools for public health precision in LMICs, which evidences the need...
Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway
Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway
Exploring the effect of Naoxintong on warfarin anticoagulation therapy and its potential mechanism, concluding that it is ...
A Novel Pathogenic Splicing Mutation of OFD1 is Responsible for a Boy with Joubert Syndrome Exhibiting Orofaciodigital Spectrum Anomalies, Polydactyly and Retinitis Pigmentosa
A Novel Pathogenic Splicing Mutation of OFD1 is Responsible for a Boy with Joubert Syndrome Exhibiting Orofaciodigital Spectrum Anomalies, Polydactyly and Retinitis Pigmentosa
Case of JS and expands the mutant spectrum of OFD1, but also enhances our understanding of the mechanism by which OFD1 is ...
Association of MiRNA Polymorphisms Involved in the PI3K/ATK/GSK3β Pathway with T2DM in a Chinese Population
Association of MiRNA Polymorphisms Involved in the PI3K/ATK/GSK3β Pathway with T2DM in a Chinese Population
Investigating the association of SNPs in miRNA genes targeting the PI3K/AKT/GSK3β pathway with Type 2 diabetes mellit...
Pharmacogenomics of Chemotherapies for Childhood Cancers in Africa: A Scoping Review
Pharmacogenomics of Chemotherapies for Childhood Cancers in Africa: A Scoping Review
Pharmacogenomic variants, such as TPMT*3A, 3C, and CYP3A53, *6, significantly impact drug metabolism in African children w...
Novel SLC16A2 Frameshift Mutation as a Cause of Allan-Herndon-Dudley Syndrome and its Implications for Carrier Screening
Novel SLC16A2 Frameshift Mutation as a Cause of Allan-Herndon-Dudley Syndrome and its Implications for Carrier Screening
Genetic cause of AHDS in a male proband and to expanding the mutation spectrum of the SLC16A2 gene
Clinicopathological and Molecular Features of Primary Inflammatory Myofibroblastic Tumor in Nasal Cavity and Paranasal Sinuses
Clinicopathological and Molecular Features of Primary Inflammatory Myofibroblastic Tumor in Nasal Cavity and Paranasal Sinuses
Investigating the clinicopathological and molecular features of primary inflammatory myofibroblastic tumor in the nasal ca...
Prevalence of CYP2C19 Variants in Patients with Cardiovascular Disease from the Yunnan-Guizhou Plateau in Southwestern China
Prevalence of CYP2C19 Variants in Patients with Cardiovascular Disease from the Yunnan-Guizhou Plateau in Southwestern China
Investigating the frequency distributions of CYP2C19 alleles in patients with cardiovascular disease. Read more
Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation
Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation
This work found a link between FAM198B and quercetin, and the regulatory effect of FAM198B on the MAPK pathway of GC.
Associations Between FTO Polymorphisms and Neuroblastoma Risk in Chinese Children
Associations Between FTO Polymorphisms and Neuroblastoma Risk in Chinese Children
Revealing that individuals with retroperitoneal Neuroblastoma and those with stage III+IV NB are more prone to exhibit FTO...
Molecular Genetic Analysis of a DMD Frameshift Mutation in a Boy with Duchenne Muscular Dystrophy by MLPA and Sanger Sequencing
Molecular Genetic Analysis of a DMD Frameshift Mutation in a Boy with Duchenne Muscular Dystrophy by MLPA and Sanger Sequencing
The combination of MLPA and Sanger sequencing technologies can help make a definite genetic diagnosis for DMD patients. Re...
Advances in the Clinical Use of Clopidogrel: A Review of Individualized Treatment Strategies and Monitoring Optimization Based on Genetic Polymorphisms
Advances in the Clinical Use of Clopidogrel: A Review of Individualized Treatment Strategies and Monitoring Optimization Based on Genetic Polymorphisms
we elucidate clopidogrel's pharmacokinetic properties and pharmacodynamic mechanisms and evaluate its clinical efficacy an...
A Case Report of Hemiplegic Migraine with Mutation in the ATP1A2 Gene
A Case Report of Hemiplegic Migraine with Mutation in the ATP1A2 Gene
Presenting a case of hemiplegic migraine that bears the potential for misdiagnosis, particularly as encephalitis. Read more
Serum IFN-γ Predicts the Therapeutic Effect of Belimumab in Refractory Lupus Nephritis Patients
Serum IFN-γ Predicts the Therapeutic Effect of Belimumab in Refractory Lupus Nephritis Patients
To evaluate belimumabf's efficacy in refractory lupus nephritis (LN) patients and identify predictive serum biomarkers for...
Bioinformatics-Based Identification of Key Prognostic Genes in Neuroblastoma with a Focus on Immune Cell Infiltration and Diagnostic Potential of VGF
Bioinformatics-Based Identification of Key Prognostic Genes in Neuroblastoma with a Focus on Immune Cell Infiltration and Diagnostic Potential of VGF
Identifying differentially expressed genes (DEGs) in neuroblastoma (NB) through comprehensive bioinformatics analysis and ...
Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension
Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension
The correlation between single nucleotide polymorphisms in selected genes (CACNA1, CACNA1D, ABCB1, ACE, ADBR2, & NOS1A...
Genetic Diversity Landscape in African Population: A Review of Implications for Personalized and Precision Medicine
Genetic Diversity Landscape in African Population: A Review of Implications for Personalized and Precision Medicine
This review aim to delineate nuanced facets, advantageous and challenging, of Africa's genetic multiplicity vis-à-v...
Immune Microenvironment Alterations and Identification of Key Diagnostic Biomarkers in Chronic Kidney Disease Using Integrated Bioinformatics and Machine Learning
Immune Microenvironment Alterations and Identification of Key Diagnostic Biomarkers in Chronic Kidney Disease Using Integrated Bioinformatics and Machine Learning
Investigating immune cell infiltration, differential gene expression, pathway enrichment in CKD to identify key diagnostic...
Hsa_circ_0078767 Enhances Osteosarcoma Chemoresistance to Doxorubicin Through the Regulation of the miR-188-3p/GPX4 Axis
Hsa_circ_0078767 Enhances Osteosarcoma Chemoresistance to Doxorubicin Through the Regulation of the miR-188-3p/GPX4 Axis
To examine hsa_circ_0078767 as a mediator of doxorubicin (DOX) resistance in OS
Prognostic Value and Immunological Role of POP7 in Clear Cell Renal Cell Carcinoma
Prognostic Value and Immunological Role of POP7 in Clear Cell Renal Cell Carcinoma
The expression & prognostic value of POP family in ccRCC were analyzed & the relationship between POP7 & immun...
16S rRNA Gene Sequencing of Gut Microbiota in Rheumatoid Arthritis Treated with 99Tc-MDP
16S rRNA Gene Sequencing of Gut Microbiota in Rheumatoid Arthritis Treated with 99Tc-MDP
Exploring effect of 99Tc-MDP treatment on composition and function of the intestinal flora, provide new information on the...
An Aging-Related lncRNA Signature Establishing for Breast Cancer Prognosis and Immunotherapy Responsiveness Prediction
An Aging-Related lncRNA Signature Establishing for Breast Cancer Prognosis and Immunotherapy Responsiveness Prediction
Our study intended to develop a prognostic risk model based on aging-related lncRNAs (AG-lncs) to foresee BC patients' out...
The Correlation of Centromere Protein Q with Diagnosis and Prognosis in Hepatocellular Carcinoma
The Correlation of Centromere Protein Q with Diagnosis and Prognosis in Hepatocellular Carcinoma
Although more specific studies are clearly needed, our study suggests that CENPQ may represent a novel biomarker and poten...
Preliminary Study on Clinical Characteristics and Pathogenesis of IQSEC2 Mutations Patients
Preliminary Study on Clinical Characteristics and Pathogenesis of IQSEC2 Mutations Patients
Preliminary Study on Clinical Characteristics and Pathogenesis of IQSEC2 Mutations Patients
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