Buerki R, Lapointe S, Solomon D, Phillips J, Perry A, Villaneuva-Meyer J, Molinaro A, Bush NAO, Taylor J, Butowski N (2019) Clinical and pathological characteristics of 52 adults with H3 K27M-mutant diffuse midline gliomas at UCSF (S14. 004). AAN Enterprises
Enomoto T, Aoki M, Hamasaki M, Abe H, Nonaka M, Inoue T, Nabeshima K (2019) Midline glioma in adults: clinicopathological, genetic, and epigenetic analysis. Neurol Med Chir. https://doi.org/10.2176/nmc.oa.2019-0168
López-Pérez CA, Franco-Mojica X, Villanueva-Gaona R, Díaz-Alba A, Rodríguez-Florido MA, Navarro VG (2022) Adult diffuse midline gliomas H3 K27-altered: review of a redefined entity. J Neuro-Oncol. https://doi.org/10.1007/s11060-022-04024-5
Picca A, Berzero G, Bielle F, Touat M, Savatovsky J, Polivka M, Trisolini E, Meunier S, Schmitt Y, Idbaih A (2018) FGFR1 actionable mutations, molecular specificities, and outcome of adult midline gliomas. Neurology 90:e2086–e2094
Article CAS PubMed Google Scholar
Solomon DA, Wood MD, Tihan T, Bollen AW, Gupta N, Phillips JJ, Perry A (2016) Diffuse midline gliomas with histone H3-K27M mutation: a series of 47 cases assessing the spectrum of morphologic variation and associated genetic alterations. Brain Pathol 26:569–580
Article CAS PubMed Google Scholar
Vuong HG, Le HT, Ngo TN, Fung K-M, Battiste JD, McNall-Knapp R, Dunn IF (2021) H3K27M-mutant diffuse midline gliomas should be further molecularly stratified: an integrated analysis of 669 patients. J Neuro-Oncol. https://doi.org/10.1007/s11060-021-03890-9
Wang Y, Feng L-l, Ji P-g, Liu J-h, Guo S-c, Zhai Y-l, Sankey EW, Wang Y, Xue Y-r, Wang N, Lou M, Xu M, Chao M, Gao G-D, Qu Y, Gong L, Wang L (2021) Clinical features and molecular markers on diffuse midline gliomas with H3K27M mutations: a 43 cases retrospective cohort study. Front Oncol. https://doi.org/10.3389/fonc.2020.602553
Article PubMed PubMed Central Google Scholar
Zheng L, Gong J, Yu T, Zou Y, Zhang M, Nie L, Chen X, Yue Q, Liu Y, Mao Q (2022) Diffuse midline gliomas with histone H3 K27M mutation in adults and children: a retrospective series of 164 cases. Am J Surg Pathol 46:863
Article PubMed PubMed Central Google Scholar
Ostrom QT, Price M, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS (2022) CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2015–2019. Neuro-Oncology 24:v1–v95
Article CAS PubMed PubMed Central Google Scholar
Eschbacher KL, Ida CM, Johnson DR, Alvi MA, Jenkins SM, Ruff MW, Kerezoudis P, Neth BJ, Pasion RM, Daniels DJ (2021) Diffuse gliomas of the brainstem and cerebellum in adults show molecular heterogeneity. Am J Surg Pathol 45:1082–1090
Bin-Alamer O, Jimenez AE, Azad TD, Bettegowda C, Mukherjee D (2022) H3K27M-altered diffuse midline gliomas among adult patients: a systematic review of clinical features and survival analysis. World Neurosurg 165:e251–e264. https://doi.org/10.1016/j.wneu.2022.06.020
Sarangi S, Wong E (2019) HOUT-05. Comparing outcomes of adult diffuse midline gliomas to glioblastoma (GBM) in young patients. Neuro-Oncology 21:vi112–vi113. https://doi.org/10.1093/neuonc/noz175.470
Article PubMed Central Google Scholar
Karremann M, Gielen GH, Hoffmann M, Wiese M, Colditz N, Warmuth-Metz M, Bison B, Claviez A, van Vuurden DG, von Bueren AO, Gessi M, Kühnle I, Hans VH, Benesch M, Sturm D, Kortmann RD, Waha A, Pietsch T, Kramm CM (2018) Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location. Neuro-Oncology 20:123–131. https://doi.org/10.1093/neuonc/nox149
Article CAS PubMed Google Scholar
Kerezoudis P, Goyal A, Lu VM, Alvi MA, Bydon M, Kizilbash SH, Burns TC (2020) The role of radiation and chemotherapy in adult patients with high-grade brainstem gliomas: results from the National Cancer Database. J Neurooncol 146:303–310. https://doi.org/10.1007/s11060-019-03374-x
Article CAS PubMed Google Scholar
Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng H, Pfister SM, Reifenberger G (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro-Oncology 23:1231–1251
Article CAS PubMed PubMed Central Google Scholar
Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM (2012) Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22:425–437. https://doi.org/10.1016/j.ccr.2012.08.024
Article CAS PubMed Google Scholar
Bechet D, Gielen GG, Korshunov A, Pfister SM, Rousso C, Faury D, Fiset P-O, Benlimane N, Lewis PW, Lu C (2014) Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas. Acta Neuropathol 128:733–741
Article CAS PubMed PubMed Central Google Scholar
Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Taylor KR, Saulnier P, Lacroix L, Mackay A (2015) Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes. Acta Neuropathol 130:815–827
Article CAS PubMed PubMed Central Google Scholar
Meyronet D, Esteban-Mader M, Bonnet C, Joly M-O, Uro-Coste E, Amiel-Benouaich A, Forest F, Rousselot-Denis C, Burel-Vandenbos F, Bourg V (2017) Characteristics of H3 K27M-mutant gliomas in adults. Neuro-Oncology 19:1127–1134
Article CAS PubMed PubMed Central Google Scholar
Daoud EV, Rajaram V, Cai C, Oberle RJ, Martin GR, Raisanen JM, White CL III, Foong C, Mickey BE, Pan E (2018) Adult brainstem gliomas with H3K27M mutation: radiology, pathology, and prognosis. J Neuropathol Exp Neurol 77:302–311
Article CAS PubMed Google Scholar
Louis DN, Giannini C, Capper D, Paulus W, Figarella-Branger D, Lopes MB, Batchelor TT, Cairncross JG, van den Bent M, Wick W (2018) cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant. Acta Neuropathol 135:639–642
Hoffman LM, DeWire M, Ryall S, Buczkowicz P, Leach J, Miles L, Ramani A, Brudno M, Kumar SS, Drissi R (2016) Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics. Acta Neuropathol Commun 4:1–8
Article PubMed PubMed Central Google Scholar
Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Statis Assoc 53:457–481
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E, Antipin Y, Reva B, Goldberg AP, Sander C, Schultz N (2012) The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2:401–404. https://doi.org/10.1158/2159-8290.Cd-12-0095
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N (2013) Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 6:pl1. https://doi.org/10.1126/scisignal.2004088
Article CAS PubMed PubMed Central Google Scholar
Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP (1982) Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5:649–655
Article CAS PubMed Google Scholar
Irvin DM, McNeill RS, Bash RE, Miller CR (2017) Intrinsic astrocyte heterogeneity influences tumor growth in glioma mouse models. Brain Pathol 27:36–50. https://doi.org/10.1111/bpa.12348
Article CAS PubMed Google Scholar
Comba A, Faisal SM, Varela ML, Hollon T, Al-Holou WN, Umemura Y, Nunez FJ, Motsch S, Castro MG, Lowenstein PR (2021) Uncovering spatiotemporal heterogeneity of high-grade gliomas: from disease biology to therapeutic implications. Front Oncol 11:703764. https://doi.org/10.3389/fonc.2021.703764
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