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Autonomy duration in patients with biopsy-only unresectable wild-type glioblastomas
Autonomy duration in patients with biopsy-only unresectable wild-type glioblastomas
“Biopsy-only” glioblastoma (BO-GB) is an understudied entity associated with a poor outcome for whom quality o...
National and institutional capacity building with international collaboration to advance pediatric neuro-oncology care in Ethiopia: a baseline need assessment survey
National and institutional capacity building with international collaboration to advance pediatric neuro-oncology care in Ethiopia: a baseline need assessment survey
Pediatric neuro-oncology (PNO), which encompasses the diagnosis and treatment of brain and spinal cord tumors in children,...
Dynamic reorganization of individual-level morphological networks in unilateral frontal lobe low-grade gliomas: a longitudinal study
Dynamic reorganization of individual-level morphological networks in unilateral frontal lobe low-grade gliomas: a longitudinal study
To characterize preoperative alterations and postoperative reorganization of gray matter volume (GMV)-based individual-lev...
MiR-148a-3p/SIRT7 axis promotes glioma progression and regulates temozolomide chemosensitivity
MiR-148a-3p/SIRT7 axis promotes glioma progression and regulates temozolomide chemosensitivity
Glioma is a highly malignant primary neoplasm of the central nervous system. Temozolomide (TMZ) is the first-line chemothe...
Using data for novel discoveries in neuro-oncology research
Using data for novel discoveries in neuro-oncology research
The study of brain and central nervous system (CNS) tumors has generated and relied upon abundant and diverse data. Robust...
Clinical utility of repeat brain biopsy in recurrent or refractory primary CNS lymphoma – a diagnostic dilemma
Clinical utility of repeat brain biopsy in recurrent or refractory primary CNS lymphoma – a diagnostic dilemma
Despite advances in therapy and improved survival for patients with primary central nervous system lymphoma (PCNSL), optim...
Circadian variation in MGMT promoter methylation and expression predicts sensitivity to temozolomide in glioblastoma
Circadian variation in MGMT promoter methylation and expression predicts sensitivity to temozolomide in glioblastoma
Recent studies show that glioblastoma (GBM) is more sensitive to temozolomide (TMZ) in the morning. In cells, inhibiting O...
Stereotactic radiosurgery for patients with brain metastases from nasopharyngeal carcinoma
Stereotactic radiosurgery for patients with brain metastases from nasopharyngeal carcinoma
The role of stereotactic radiosurgery (SRS) for patients with brain metastases from nasopharyngeal carcinoma (NPC) has yet...
Brain state theory as a comprehensive model for addressing the “non-eloquent” brain in glioma surgery
Brain state theory as a comprehensive model for addressing the “non-eloquent” brain in glioma surgery
Glioma surgery often results in significant cognitive deficits that magnify patient morbidity and mortality. Traditional c...
Investigating glioblastoma chemoresistance: a meta-analysis of microRNA signatures and gene networks
Investigating glioblastoma chemoresistance: a meta-analysis of microRNA signatures and gene networks
Chemoresistance is a significant issue in glioblastoma (GBM) treatment due to recurrence, poor survival and limited salvag...
SUV-max of Ga-DOTATATE PET/CT correlates with WHO grade and RNA risk classification in meningioma
SUV-max of Ga-DOTATATE PET/CT correlates with WHO grade and RNA risk classification in meningioma
68Ga-DOTATATE binds to somatostatin receptors (SSTR) and is used for PET/CT imaging for diagnosing meningioma and guiding ...
Navigating heterogeneity in resected brain metastases: molecular stratification and multimodal therapeutic strategies
Navigating heterogeneity in resected brain metastases: molecular stratification and multimodal therapeutic strategies
Resection of brain metastases mitigates mass effect and herniation risk while extending overall survival. This cohort stud...
Clinical predictors of pseudoprogression in glioblastoma: a retrospective cohort analysis
Clinical predictors of pseudoprogression in glioblastoma: a retrospective cohort analysis
Distinguishing pseudoprogression (PsP) from true progression (TP) in glioblastoma (GBM) remains a diagnostic challenge, ye...
Long-term outcomes and toxicity of radiotherapy for WHO Grade II and III meningiomas: a retrospective analysis of 98 patients
Long-term outcomes and toxicity of radiotherapy for WHO Grade II and III meningiomas: a retrospective analysis of 98 patients
This retrospective study evaluated outcomes and toxicity in patients with WHO Grade II and III meningiomas treated with mo...
Neurocognitive function in lower grade glioma patients selected for proton radiotherapy: real-world data from a prospective cohort study
Neurocognitive function in lower grade glioma patients selected for proton radiotherapy: real-world data from a prospective cohort study
To determine neurocognitive function (NCF) profiles of patients with lower grade glioma (LGG) eligible to undergo proton r...
Prognostic revalidation of RANO categories for extent of resection in glioblastoma: a reconstruction of individual patient data
Prognostic revalidation of RANO categories for extent of resection in glioblastoma: a reconstruction of individual patient data
The RANO classification for glioblastoma defines resection categories based on volumetric tumor assessments, aiming to sta...
RAPID, a multicenter collaboration for the study of craniopharyngiomas: challenges, opportunities, and future directions
RAPID, a multicenter collaboration for the study of craniopharyngiomas: challenges, opportunities, and future directions
Competing interests Dr. Little was an investor in Kogent Surgical a...
Comparison of adjuvant radiation versus observation and salvage radiation after subtotal resection of a WHO grade I skull base meningioma: a propensity score-adjusted analysis
Comparison of adjuvant radiation versus observation and salvage radiation after subtotal resection of a WHO grade I skull base meningioma: a propensity score-adjusted analysis
In patients with subtotal resection (STR) of WHO grade I skull base meningiomas, treatment strategies of adjuvant radiatio...
The association between postoperative photon radiotherapy dose and disease control and salvage treatment in pediatric and adolescent ependymoma: a multi-institutional investigation
The association between postoperative photon radiotherapy dose and disease control and salvage treatment in pediatric and adolescent ependymoma: a multi-institutional investigation
We characterized the association between photon radiation dose (< 59.4 versus ≥ 59.4 Gy)...
Establishment and transcriptomic characteristics of radio-resistant meningioma cell lines
Establishment and transcriptomic characteristics of radio-resistant meningioma cell lines
Radio-resistance poses a significant challenge in meningioma treatment. This study aimed to establish radio-resistant meni...
Clinical predictors of overall survival in very elderly meningioma patients: a surveillance, epidemiology, and end results (SEER) database analysis
Clinical predictors of overall survival in very elderly meningioma patients: a surveillance, epidemiology, and end results (SEER) database analysis
Surgical resection is the gold standard of management for symptomatic intracranial meningiomas. However, surgical interven...
Ciprofol reduces postoperative glioma recurrence by promoting MAPK11-PML phosphorylation: insights from transcriptomic and proteomic analysis
Ciprofol reduces postoperative glioma recurrence by promoting MAPK11-PML phosphorylation: insights from transcriptomic and proteomic analysis
Glioma, the most common malignant tumor of the central nervous system, has a high postoperative recurrence rate. While Cip...
Improving IL12 immunotherapy in glioblastoma by targeting the long noncoding RNA
Improving IL12 immunotherapy in glioblastoma by targeting the long noncoding RNA
The potent antitumor effects of interleukin 12 (IL12) gene therapy in glioblastoma (GBM) are significantly attenuated by t...
Current clinical trials for craniopharyngiomas: what’s on the horizon?
Current clinical trials for craniopharyngiomas: what’s on the horizon?
Craniopharyngiomas are histologically low-grade tumors in the sellar/suprasellar region that grow close to critical struct...
Extra-central nervous system metastasis from high-grade glioma: a single-institution experience
Extra-central nervous system metastasis from high-grade glioma: a single-institution experience
Extra-central nervous system metastasis (ECM) from glioblastoma and other high-grade gliomas (HGGs) is exceedingly rare, l...
Peritumoral edema resolves infrequently in surgically treated patients with intracranial meningioma– a retrospective study of 279 meningioma patients
Peritumoral edema resolves infrequently in surgically treated patients with intracranial meningioma– a retrospective study of 279 meningioma patients
The resolution of peritumoral brain edema (PTBE) following surgery for intracranial meningioma (IM) is poorly understood. ...
Characterizing the molecular and spatial heterogeneity of midline gliomas in adults: a single institution analysis
Characterizing the molecular and spatial heterogeneity of midline gliomas in adults: a single institution analysis
Primary gliomas arising within midline structures of the central nervous system are associated with a worse prognosis comp...
Gene therapy and genome-editing for schwannoma in -related schwannomatosis: current understanding and future directions
Gene therapy and genome-editing for schwannoma in -related schwannomatosis: current understanding and future directions
NF2-related schwannomatosis (NF2-SWN) is a rare genetic disorder characterized by bilateral vestibular schwannomas. NF2-SW...
The 4S of spinal astrocytoma: specific location, syrinx, spasticity and score on Modified Mccormick Scale (MMS) predict long term outcomes in patients undergoing surgical resection of intramedullary spinal astrocytomas
The 4S of spinal astrocytoma: specific location, syrinx, spasticity and score on Modified Mccormick Scale (MMS) predict long term outcomes in patients undergoing surgical resection of intramedullary spinal astrocytomas
The aim of this study was to explore the factors that could predict long term clinical outcomes in SA. A retrospective stu...
Clinical trial design for novel targeted agents in neuro-oncology
Clinical trial design for novel targeted agents in neuro-oncology
Biomarker-based clinical trials investigating targeted treatments for brain tumors have surged due to better access to bio...
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