SCI Abstract

search
+
Trends in real-world outcomes of patients with metastatic renal cell cancer in the recent treatment era: a single-institution analysis
Trends in real-world outcomes of patients with metastatic renal cell cancer in the recent treatment era: a single-institution analysis
Systemic therapy for metastatic renal cell cancer (mRCC) has changed significantly due to randomized controlled trial resu...
Survival impact and recurrence prediction using oncologic resectability classification in hepatocellular carcinoma following hepatic resection: a Japanese multi-center study
Survival impact and recurrence prediction using oncologic resectability classification in hepatocellular carcinoma following hepatic resection: a Japanese multi-center study
The oncological criteria of resectability for HCC were reported by the Japanese Expert Consensus 2023. The relationship be...
Risk stratification for recurrence after nephrectomy in high-risk renal cell carcinoma patients
Risk stratification for recurrence after nephrectomy in high-risk renal cell carcinoma patients
To identify prognostic factors that guide adjuvant therapy decisions, we investigated factors predicting recurrence in pat...
Optimizing radiation therapy for merkel cell carcinoma: evaluating prognostic factors and treatment outcomes
Optimizing radiation therapy for merkel cell carcinoma: evaluating prognostic factors and treatment outcomes
Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer. Surgery and radiation therapy (RT) are comm...
Clinical advantages of two vs. three courses of neoadjuvant chemotherapy using docetaxel + cisplatin + 5-fluorouracil to improve preoperative nutritional status and mitigate decreasing skeletal muscle in resectable esophageal cancer
Clinical advantages of two vs. three courses of neoadjuvant chemotherapy using docetaxel + cisplatin + 5-fluorouracil to improve preoperative nutritional status and mitigate decreasing skeletal muscle in resectable esophageal cancer
Neoadjuvant chemotherapy (NAC) using docetaxel/cisplatin/5-fluorouracil (DCF) for locally advanced esophageal cancer (EC) ...
Onco-nephrology in clinical practice: pharmacokinetics, monitoring, and treatment strategies for patients with cancer and impaired renal function
Onco-nephrology in clinical practice: pharmacokinetics, monitoring, and treatment strategies for patients with cancer and impaired renal function
Renal dysfunction is common in patients with cancer and affects their pharmacokinetics, thereby altering treatment efficac...
The nationwide survey of Japanese public opinion about off-label use of anticancer drugs recommended by comprehensive genomic profiling
The nationwide survey of Japanese public opinion about off-label use of anticancer drugs recommended by comprehensive genomic profiling
Comprehensive genomic profiling (CGP)-guided precision medicine enables identification of molecular-based recommended ther...
Advances in liquid biopsy for bone and soft-tissue sarcomas
Advances in liquid biopsy for bone and soft-tissue sarcomas
Bone and soft-tissue sarcomas are a heterogeneous group of malignant tumors originating from mesenchymal tissues, accounti...
Effect of pretreatment vascular endothelial growth factor inhibitor use on the safety and efficacy of trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer
Effect of pretreatment vascular endothelial growth factor inhibitor use on the safety and efficacy of trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer
The effect of vascular endothelial growth factor (VEGF) inhibitor pretreatment on clinical outcomes of trifluridine/tipira...
Efficacy of cisplatin-based neoadjuvant chemotherapy and risk factors for residual extravesical disease in muscle-invasive bladder cancer: insights from a nationwide cohort
Efficacy of cisplatin-based neoadjuvant chemotherapy and risk factors for residual extravesical disease in muscle-invasive bladder cancer: insights from a nationwide cohort
Cisplatin-based neoadjuvant chemotherapy (NAC) improves survival in muscle-invasive bladder cancer (MIBC) as long as disea...
Real-world treatment outcomes before and after chemoimmunotherapy approval in -mutant NSCLC after EGFR-TKI failure: a Japanese cohort study
Real-world treatment outcomes before and after chemoimmunotherapy approval in -mutant NSCLC after EGFR-TKI failure: a Japanese cohort study
In Japan, chemoimmunotherapy was approved as treatment for advanced or recurrent non-small-cell lung cancer (NSCLC), inclu...
Burden and trajectories of biliary tract malignancies in Taiwan from 1998 to 2022
Burden and trajectories of biliary tract malignancies in Taiwan from 1998 to 2022
Biliary tract cancers, though relatively rare, exhibit wide variations in incidence rates across countries. We conducted a...
Impact of prior COVID-19 infection on perioperative outcomes in non-small cell lung cancer patients: a prospective observational cohort study
Impact of prior COVID-19 infection on perioperative outcomes in non-small cell lung cancer patients: a prospective observational cohort study
COVID-19 infection may induce persistent pulmonary sequelae, potentially elevating perioperative risks in non-small cell l...
Comparison of clinical features by primary site in patients with biliary tract cancer who received gemcitabine-based chemotherapy: an exploratory analysis of JCOG1113
Comparison of clinical features by primary site in patients with biliary tract cancer who received gemcitabine-based chemotherapy: an exploratory analysis of JCOG1113
Biliary tract cancers (BTCs) are heterogenous malignancies including gallbladder cancer (GBC), intrahepatic cholangiocarci...
The Metazoan SpoT Homolog 1 promotes ferroptosis by regulating the intracellular redox cycle and iron levels in hepatocellular carcinoma
The Metazoan SpoT Homolog 1 promotes ferroptosis by regulating the intracellular redox cycle and iron levels in hepatocellular carcinoma
Ferroptosis, a form of programmed cell death, is a potential target for cancer therapy. Metazoan SpoT Homolog 1 (MESH1) po...
Predictors of long‑term survival in patients with stage IV colorectal cancer with primary tumor resection: a multi-center retrospective analysis
Predictors of long‑term survival in patients with stage IV colorectal cancer with primary tumor resection: a multi-center retrospective analysis
Primary tumor resection is an option for patients with stage IV colorectal cancer (CRC). However, there is still no reliab...
The value of vaginal cytology for postoperative surveillance of endometrial cancer
The value of vaginal cytology for postoperative surveillance of endometrial cancer
The value of conducting vaginal cytology surveillance after endometrial cancer (EC) surgery has not been fully established...
Real-world application of comprehensive genomic profiling for gynecological malignancies: a multicenter observational study
Real-world application of comprehensive genomic profiling for gynecological malignancies: a multicenter observational study
The actual status of comprehensive genomic profiling (CGP) applications in Japan has not been clarified. We conducted a mu...
Lateral node metastasis in low rectal cancer as a hallmark to predict recurrence patterns
Lateral node metastasis in low rectal cancer as a hallmark to predict recurrence patterns
Lateral node metastasis confers a poor prognosis in rectal cancer. Several multidisciplinary treatments have been proposed...
Effects of aging on complications following robot-assisted radical prostatectomy
Effects of aging on complications following robot-assisted radical prostatectomy
For prostate cancer (PCa) in the elderly, including patients ≥ 80 years, the safety of robot-as...
Discovery and validation of Hsa-microRNA-3665 promoter methylation as a potential biomarker for the prognosis of esophageal squaous cell carcinoma
Discovery and validation of Hsa-microRNA-3665 promoter methylation as a potential biomarker for the prognosis of esophageal squaous cell carcinoma
Methylation of microRNA (miRNA) promoters associated with diseases is a common epigenetic mechanism in the development of ...
The efficacy and safety of lenvatinib plus pembrolizumab in vulnerable patients with metastatic or recurrent endometrial cancer: a single institution experience
The efficacy and safety of lenvatinib plus pembrolizumab in vulnerable patients with metastatic or recurrent endometrial cancer: a single institution experience
Effective management with second-line therapy with the lenvatinib + pembrolizumab regimen for patients with ad...
Efficacy and safety of mosunetuzumab monotherapy for Japanese patients with relapsed/refractory follicular lymphoma: FLMOON-1
Efficacy and safety of mosunetuzumab monotherapy for Japanese patients with relapsed/refractory follicular lymphoma: FLMOON-1
In a global phase I/II study (GO29781; NCT02500407), single-agent mosunetuzumab had a manageable safety profile and induce...
Characterization of PSA dynamics and oncological outcomes in patients with metastatic hormone-sensitive prostate cancer treated with androgen receptor signaling inhibitors
Characterization of PSA dynamics and oncological outcomes in patients with metastatic hormone-sensitive prostate cancer treated with androgen receptor signaling inhibitors
This study investigated the characteristics of prostate-specific antigen (PSA) dynamics when androgen receptor signaling i...
Impact of presurgical systemic therapy on perioperative outcomes of renal cell carcinoma with inferior vena cava tumor thrombus
Impact of presurgical systemic therapy on perioperative outcomes of renal cell carcinoma with inferior vena cava tumor thrombus
Surgery for inferior vena cava tumor thrombus (IVC-TT) in patients with renal cell carcinoma (RCC) is highly invasive and ...
Evaluating the impact of atezolizumab on febrile neutropenia occurrence in patients with NSCLC undergoing chemotherapy in Japan: a real-world post-marketing database study
Evaluating the impact of atezolizumab on febrile neutropenia occurrence in patients with NSCLC undergoing chemotherapy in Japan: a real-world post-marketing database study
Febrile neutropenia (FN) is a recognised adverse event associated with chemotherapy. This study investigates the impact of...
Treatment-related skin reactions in enfortumab vedotin as a surrogate marker of survival and treatment response
Treatment-related skin reactions in enfortumab vedotin as a surrogate marker of survival and treatment response
Treatment-related skin reactions (TRSRs) induced by enfortumab vedotin (EV) targeting nectin-4 are among the most common a...
Age-related genomic alterations and chemotherapy sensitivity in osteosarcoma: insights from cancer genome profiling analyses
Age-related genomic alterations and chemotherapy sensitivity in osteosarcoma: insights from cancer genome profiling analyses
Osteosarcoma, the most common primary bone malignancy, has a complex genetic basis and two incidence peaks. In younger pat...
Improved prognosis of de novo metastatic prostate cancer after an introduction of life-prolonging agents for castration-resistant prostate cancer
Improved prognosis of de novo metastatic prostate cancer after an introduction of life-prolonging agents for castration-resistant prostate cancer
In Japan, since 2014, new treatments such as androgen receptor signaling inhibitors and cabazitaxel have become applicable...
Efficacy of androgen receptor signaling inhibitors in combination with androgen deprivation therapy for castration-sensitive metastatic prostate cancer: a retrospective analysis in a Japanese cohort
Efficacy of androgen receptor signaling inhibitors in combination with androgen deprivation therapy for castration-sensitive metastatic prostate cancer: a retrospective analysis in a Japanese cohort
This study aimed to evaluate the efficacy of androgen receptor signaling inhibitors (ARSIs) combined with androgen depriva...
Load More
format_indent_increase