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venom modulates colorectal carcinoma signaling pathways and induces apoptosis
venom modulates colorectal carcinoma signaling pathways and induces apoptosis
Colorectal cancer (CRC) is a significant global health concern, often challenging to treat effectively with conventional m...
Huntingtin-interacting protein 1 in cancer progression: a path less explored
Huntingtin-interacting protein 1 in cancer progression: a path less explored
Huntingtin-interacting protein 1 (HIP1) is a multi-domain heterodimeric protein mainly involved in clathrin-mediated endoc...
A review on the advancement of polydopamine (PDA)-based nanomaterials for cancer treatment
A review on the advancement of polydopamine (PDA)-based nanomaterials for cancer treatment
The significance of cancer treatment research lies in addressing the high incidence of cancer, overcoming treatment challe...
Up-regulation of thrombospondin-1 inhibits the progression of gallbladder cancer
Up-regulation of thrombospondin-1 inhibits the progression of gallbladder cancer
Gallbladder cancer, the most prevalent malignant neoplasm of the biliary tract, has garnered significant attention due to ...
Antitumor potential of ivermectin against T-cell lymphoma-bearing hosts
Antitumor potential of ivermectin against T-cell lymphoma-bearing hosts
Ivermectin, a broad-spectrum antiparasitic agent from the ivermectin family, has shown promising anticancer potential. Ori...
Mechanism of etoposide resistance in small cell lung cancer and the potential therapeutic options
Mechanism of etoposide resistance in small cell lung cancer and the potential therapeutic options
Small cell lung cancer (SCLC) is a type of high-grade neuroendocrine malignancy with low gene mutation. Chemotherapy is th...
Mechanism of Dahuang–Dangshen drug pairs in the treatment of HCC based on network pharmacology, bioinformatics, molecular docking and experimental verification
Mechanism of Dahuang–Dangshen drug pairs in the treatment of HCC based on network pharmacology, bioinformatics, molecular docking and experimental verification
The anti-hepatocellular carcinoma (HCC) effect of the active ingredients of natural Chinese herbal medicine has become a h...
Omeprazole attenuates irradiation-induced lung injury through the suppression of apoptosis and oxidative stress in mice
Omeprazole attenuates irradiation-induced lung injury through the suppression of apoptosis and oxidative stress in mice
Radiation therapy is an effective treatment for patients with malignant thoracic tumors, but it can cause lung damage. Ome...
Identification of a novel tRNA-derived small RNA fragment, tRF-16-2YU04DE, with the potential of inhibiting endometrial cancer progression
Identification of a novel tRNA-derived small RNA fragment, tRF-16-2YU04DE, with the potential of inhibiting endometrial cancer progression
As the second most prevalent gynecological malignancy, the incidence and mortality of endometrial cancer (EC) are rising. ...
Molecular mechanisms and clinical significance of perineural invasion in malignancies: the pivotal role of tumor-associated Schwann cells in cancer progression and metastasis
Molecular mechanisms and clinical significance of perineural invasion in malignancies: the pivotal role of tumor-associated Schwann cells in cancer progression and metastasis
Perineural invasion (PNI) is a pathological process wherein cancer cells invade and spread along peripheral nerves, contri...
Peptide-based drugs in immunotherapy: current advances and future prospects
Peptide-based drugs in immunotherapy: current advances and future prospects
In immunotherapy, peptide-based medications are showing great promise as a new class of therapies that can be used to trea...
DCAF13 influences breast cancer chemotherapy resistance through metabolic reprogramming by regulating c-Myc expression
DCAF13 influences breast cancer chemotherapy resistance through metabolic reprogramming by regulating c-Myc expression
Chemotherapy resistance remains a major obstacle in breast cancer treatment. This study identifies DCAF13, a substrate rec...
Innovative PEGylated chitosan nanocarriers for co-delivery of doxorubicin and CpG in breast cancer therapy: Preparation, characterization, and immunotherapeutic potential
Innovative PEGylated chitosan nanocarriers for co-delivery of doxorubicin and CpG in breast cancer therapy: Preparation, characterization, and immunotherapeutic potential
This study aimed to design polyethylene glycol (PEG)ylated chitosan (CS, PEG-CS) nanoparticles for the co-delivery of doxo...
Promising immunotherapeutic treatments for colon cancer
Promising immunotherapeutic treatments for colon cancer
Colon cancer continues to predominate as one of the most common causes of morbidity and mortality worldwide due to its sub...
CAR T-cell therapy in renal cell carcinoma: opportunities, challenges, and new strategies to overcome
CAR T-cell therapy in renal cell carcinoma: opportunities, challenges, and new strategies to overcome
Immunotherapy is a biological treatment for cancer that utilizes substances sourced from live organisms. Immunotherapy enc...
Innovative nanoparticle strategies for treating oral cancers
Innovative nanoparticle strategies for treating oral cancers
Conventional therapies for oral squamous cell carcinoma (OSCC), a serious worldwide health problem, are frequently constra...
TGFBI promotes EMT and perineural invasion of pancreatic cancer via PI3K/AKT pathway
TGFBI promotes EMT and perineural invasion of pancreatic cancer via PI3K/AKT pathway
Pancreatic cancer is a highly lethal malignancy, and perineural invasion (PNI) is a common pathological feature that signi...
Effectiveness of complete decongestive therapy for upper extremity breast cancer-related lymphedema: a review of systematic reviews
Effectiveness of complete decongestive therapy for upper extremity breast cancer-related lymphedema: a review of systematic reviews
Breast cancer-related lymphedema (BCRL) remains a challenging condition impacting function and quality of life. Complete d...
Post-operative care for patients following surgical treatment of lymphedema
Post-operative care for patients following surgical treatment of lymphedema
Surgical treatments are promising for the treatment of lymphedema. It is important for patients, healthcare providers, and...
Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel
Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel
Several recent studies have investigated the validity of precautionary practices for lymphedema risk reduction after breas...
Self-assembled nanoparticles of alginate and paclitaxel-triphenylphosphonium for mitochondrial apoptosis targeting
Self-assembled nanoparticles of alginate and paclitaxel-triphenylphosphonium for mitochondrial apoptosis targeting
Paclitaxel (PTX), an antimitotic drug from the taxanes group, prevents the proliferation of breast cancer cells through mi...
Understanding the chemistry & pharmacology of antibody–drug conjugates in triple-negative breast cancer with special reference to exatecan derivatives
Understanding the chemistry & pharmacology of antibody–drug conjugates in triple-negative breast cancer with special reference to exatecan derivatives
In the spectrum of breast malignancies, triple-negative breast cancer is the most widely spreading subtype of breast cance...
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a leading liver cancer that significantly impacts global life expectancy and remains cha...
Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery
Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery
Glioblastoma (GBM) is a highly prevalent and aggressive brain tumor in adults with limited treatment response, leading to ...
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer
As the first anti-HER2 targeted agent approved by FDA in 1998, Trastuzumab has significantly improved the outcome of patie...
Letter to the editor on “Targeted gene therapy for cancer: the impact of microRNA multipotentiality”
Letter to the editor on “Targeted gene therapy for cancer: the impact of microRNA multipotentiality”
Cite this articleAmeya, K.P., Sekar, D. Letter to the editor on “Targeted gene therapy for cancer: the impact of microRNA ...
CAP superfamily proteins in human: a new target for cancer therapy
CAP superfamily proteins in human: a new target for cancer therapy
The CAP (Cysteine-rich secretory protein, Antigen 5, and Pathogenesis-related protein 1) superfamily proteins (CAP protein...
The role of molecular biomarkers in recurrent glioblastoma trials: an assessment of the current trial landscape of genome-driven oncology
The role of molecular biomarkers in recurrent glioblastoma trials: an assessment of the current trial landscape of genome-driven oncology
Cite this articleAmeya, K.P., Sekar, D. The role of molecular biomarkers in recurrent glioblastoma trials: an assessment o...
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma
Radiotherapy is important in treating esophageal squamous cell carcinoma (ESCC) comprehensively. Resistance to radiotherap...
lncRNAs’p potential roles in the pathogenesis of cancer via interacting with signaling pathways; special focus on lncRNA-mediated signaling dysregulation in lung cancer
lncRNAs’p potential roles in the pathogenesis of cancer via interacting with signaling pathways; special focus on lncRNA-mediated signaling dysregulation in lung cancer
Lung cancer ranks among the most lethal types of cancer globally, with a high occurrence and fatality rate. The spread of ...
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