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The causal relationships between mitochondria and six types of cancer: a Mendelian randomization study
The causal relationships between mitochondria and six types of cancer: a Mendelian randomization study
Mitochondria play a multifaceted role in tumorigenesis, influencing energy metabolism, redox balance, and apoptosis. Howev...
Gadoxetic acid-enhanced MRI for identifying cholangiocyte phenotype hepatocellular carcinoma by interpretable machine learning: individual application of SHAP
Gadoxetic acid-enhanced MRI for identifying cholangiocyte phenotype hepatocellular carcinoma by interpretable machine learning: individual application of SHAP
Cholangiocyte phenotype hepatocellular carcinoma (HCC) is highly invasive. This study aims to develop and validate an opti...
HbA1c levels and breast cancer prognosis in women without diabetes
HbA1c levels and breast cancer prognosis in women without diabetes
Diabetes is associated with impaired breast cancer prognosis; however, the effectiveness of glycosylated hemoglobin (HbA1c...
Autologous stem cell transplantation for adults with Philadelphia-negative acute lymphoblastic leukemia in first complete remission. A study by the Acute Leukemia Working Party of the EBMT
Autologous stem cell transplantation for adults with Philadelphia-negative acute lymphoblastic leukemia in first complete remission. A study by the Acute Leukemia Working Party of the EBMT
The role of autologous hematopoietic stem cell transplantation (AHSCT) in adults with Philadelphia chromosome-negative acu...
Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis
Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis
The introduction of three kinds of magnetic resonance imaging-guided prostate biopsies (MRI-PB) has changed the paradigm r...
A new tumor-treating device OM-100 with low-frequency magnetic fields inhibits proliferation and metastasis in liver cancer
A new tumor-treating device OM-100 with low-frequency magnetic fields inhibits proliferation and metastasis in liver cancer
This study aims to investigate a novel instrument OM-100 with low-frequency magnetic fields (LFMFs) for its potential appl...
Prognostic value of FDX1, the cuprotosis key gene, and its prediction models across imaging modalities and histology
Prognostic value of FDX1, the cuprotosis key gene, and its prediction models across imaging modalities and histology
Cuprotosis has been identified as a novel way of cell death. The key regulator ferredoxin 1 (FDX1) was explored via pan-ca...
Second primary cancers in patients with a pharyngeal index tumour: a register-based cohort study
Second primary cancers in patients with a pharyngeal index tumour: a register-based cohort study
While prior research on the SPC (second primary cancer) risk among pharyngeal carcinoma (PC) patients has been conducted i...
Study protocol of an exercise and nutrition intervention for ovarian cancer patients during and after first-line chemotherapy (BENITA) - a randomized controlled trial
Study protocol of an exercise and nutrition intervention for ovarian cancer patients during and after first-line chemotherapy (BENITA) - a randomized controlled trial
In ovarian cancer frequently reported side effects are muscle wasting and malnutrition, leading to frailty, decreased heal...
Utilizing radiomics and dosiomics with AI for precision prediction of radiation dermatitis in breast cancer patients
Utilizing radiomics and dosiomics with AI for precision prediction of radiation dermatitis in breast cancer patients
This study explores integrating clinical features with radiomic and dosiomic characteristics into AI models to enhance the...
Hypopituitarism after gamma knife radiosurgery for pituitary adenomas: long-term results from a single-center experience
Hypopituitarism after gamma knife radiosurgery for pituitary adenomas: long-term results from a single-center experience
The aim of this study was to investigate the incidence and risk factors of new-onset hypopituitarism after gamma knife rad...
Plasma-derived exosomal long noncoding RNAs of pancreatic cancer patients as novel blood-based biomarkers of disease
Plasma-derived exosomal long noncoding RNAs of pancreatic cancer patients as novel blood-based biomarkers of disease
Pancreatic cancer (PaCa) is one of the most intractable and fatal malignancies and is associated with the dysregulation of...
Salivary 8-hydroxy-2′-deoxyguanosine levels in patients with oral cancer: a systematic review and meta-analysis
Salivary 8-hydroxy-2′-deoxyguanosine levels in patients with oral cancer: a systematic review and meta-analysis
DNA is an important target for oxidative attack and its modification may increase the risk of mutagenesis. The aim of this...
Advantage of whole-mount histopathology in prostate cancer: current applications and future prospects
Advantage of whole-mount histopathology in prostate cancer: current applications and future prospects
Whole-mount histopathology (WMH) has been a powerful tool to investigate the characteristics of prostate cancer. However, ...
Plasma extracellular vesicles in meningioma patients following radiotherapy as liquid biopsy- a prospective explorative biomarker study (ARO 2023-05/AG-NRO-07)
Plasma extracellular vesicles in meningioma patients following radiotherapy as liquid biopsy- a prospective explorative biomarker study (ARO 2023-05/AG-NRO-07)
While surgical resection remains the primary treatment approach for symptomatic or growing meningiomas, radiotherapy repre...
Do beta-blockers reduce negative intrusive thoughts and anxiety in cancer survivors? – An emulated trial
Do beta-blockers reduce negative intrusive thoughts and anxiety in cancer survivors? – An emulated trial
High rates of negative intrusive thoughts have been reported among cancer patients. Prevalent users of beta-block...
Binimetinib in combination with nivolumab or nivolumab and ipilimumab in patients with previously treated microsatellite-stable metastatic colorectal cancer with RAS mutations in an open-label phase 1b/2 study
Binimetinib in combination with nivolumab or nivolumab and ipilimumab in patients with previously treated microsatellite-stable metastatic colorectal cancer with RAS mutations in an open-label phase 1b/2 study
In patients with previously treated RAS-mutated microsatellite-stable (MSS) metastatic colorectal cancer (mCRC), ...
Nomogram incorporating Epstein-Barr virus DNA and a novel immune-nutritional marker for survival prediction in nasopharyngeal carcinoma
Nomogram incorporating Epstein-Barr virus DNA and a novel immune-nutritional marker for survival prediction in nasopharyngeal carcinoma
Since Immune response, nutritional status and Epstein–Barr Virus (EBV) DNA status have been confirmed to be relevant...
CD147 promotes breast cancer migration and invasion by inducing epithelial-mesenchymal transition via the MAPK/ERK signaling pathway
CD147 promotes breast cancer migration and invasion by inducing epithelial-mesenchymal transition via the MAPK/ERK signaling pathway
CD147, a transmembrane glycoprotein, has been implicated in various cancer-related processes but its role in breast cancer...
Impact of perioperative decreased serum albumin level on anastomotic leakage in esophageal squamous cell carcinoma patients treated with neoadjuvant chemotherapy followed by minimally invasive esophagectomy
Impact of perioperative decreased serum albumin level on anastomotic leakage in esophageal squamous cell carcinoma patients treated with neoadjuvant chemotherapy followed by minimally invasive esophagectomy
Anastomotic leakage (AL) is a severe complication following esophagectomy with high mortality. Perioperative decreased ser...
Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancer
Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancer
Breast cancer (BC) patients tend to suffer from distant metastasis, especially bone metastasis. All the analysis based on ...
Immediate histologic correlation in patients with different HPV genotypes and ages: a single center analysis in China
Immediate histologic correlation in patients with different HPV genotypes and ages: a single center analysis in China
Human papillomavirus (HPV) has been confirmed as a major causative factor for malignant transformation of cervical epithel...
Dynamic profiling of immune microenvironment during anti-PD-1 immunotherapy for head and neck squamous cell carcinoma: the IPRICE study
Dynamic profiling of immune microenvironment during anti-PD-1 immunotherapy for head and neck squamous cell carcinoma: the IPRICE study
Immune checkpoint inhibitors of programmed cell death protein 1 (PD-1) represent a significant breakthrough in treating he...
Phase I dose escalation study and pilot efficacy analysis of LXI-15029, a novel mTOR dual inhibitor, in Chinese subjects with advanced malignant solid tumors
Phase I dose escalation study and pilot efficacy analysis of LXI-15029, a novel mTOR dual inhibitor, in Chinese subjects with advanced malignant solid tumors
The mammalian target of rapamycin (mTOR) kinase, a central component of the PI3K/AKT/mTOR pathway, plays a critical role i...
A population-based analysis of hematological malignancies from a French-West-Indies cancer registry’s data (2009–2018)
A population-based analysis of hematological malignancies from a French-West-Indies cancer registry’s data (2009–2018)
A worldwide increased incidence of HM has been marked in recent decades. Therefore, to update epidemiological characterist...
Cancer-associated fibroblasts induce sorafenib resistance of hepatocellular carcinoma cells through CXCL12/FOLR1
Cancer-associated fibroblasts induce sorafenib resistance of hepatocellular carcinoma cells through CXCL12/FOLR1
Due to the high drug resistance of hepatocellular carcinoma (HCC), sorafenib has limited efficacy in the treatment of adva...
Significance of circulating tumor cells detection in tumor diagnosis and monitoring
Significance of circulating tumor cells detection in tumor diagnosis and monitoring
To detect circulating tumor cells (CTCs) in the peripheral blood of patients with tumor, and to analyze the significance o...
A novel patient-derived immortalised cell line of myxofibrosarcoma: a tool for preclinical drugs testing and the generation of near-patient models
A novel patient-derived immortalised cell line of myxofibrosarcoma: a tool for preclinical drugs testing and the generation of near-patient models
Myxofibrosarcoma is a rare malignant soft tissue sarcoma characterised by multiple local recurrence and can become of high...
A practical prognostic peripheral blood-based risk model for the evaluation of the likelihood of a response and survival of metastatic cancer patients treated with immune checkpoint inhibitors
A practical prognostic peripheral blood-based risk model for the evaluation of the likelihood of a response and survival of metastatic cancer patients treated with immune checkpoint inhibitors
Less than half of unselected metastatic cancer patients benefit from the immune checkpoint inhibitor (ICI) therapy. System...
Refining gastric cancer staging: examining the interplay between number and anatomical location of metastatic lymph nodes - a retrospective multi-institutional study
Refining gastric cancer staging: examining the interplay between number and anatomical location of metastatic lymph nodes - a retrospective multi-institutional study
The current gastric cancer staging system relies on the number of metastatic lymph nodes (MLNs) for nodal stage determinat...
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