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Factors Influencing Immunotherapy Utilization in Stage IV Pancreatic Cancer: Impact of Race and Socioeconomics in the U.S
Factors Influencing Immunotherapy Utilization in Stage IV Pancreatic Cancer: Impact of Race and Socioeconomics in the U.S
Pancreatic ductal adenocarcinoma (PDAC), a highly lethal cancer with a poor prognosis, is expected to become the second de...
Immunohistochemical Expression of ROR2 in Gastrointestinal Stromal Tumor
Immunohistochemical Expression of ROR2 in Gastrointestinal Stromal Tumor
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors affecting the digestive tract, comprising ap...
Role of Interleukins in Pancreatic Cancer: A Literature Review
Role of Interleukins in Pancreatic Cancer: A Literature Review
This review article summarizes the pathophysiological aspects of interleukins (ILs) including IL-1, IL-2, IL-3, IL-4, IL-5...
Exceptional Response to Pembrolizumab in HER2-Positive Gallbladder Carcinoma with High Tumor Mutational Burden
Exceptional Response to Pembrolizumab in HER2-Positive Gallbladder Carcinoma with High Tumor Mutational Burden
Patients with advanced cholangiocarcinoma, including gallbladder cancer, typically have a poor prognosis owing to limited ...
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
As long-term survival improves after allogeneic hematopoietic stem cell transplantation (HSCT), the risk for secondary sol...
Patterns and Predictors of Recurrence After Curative Resection of Colorectal Liver Metastasis (CRLM)
Patterns and Predictors of Recurrence After Curative Resection of Colorectal Liver Metastasis (CRLM)
Our study aims to determine the predictors and patterns of relapses after curative colorectal liver metastasis (CRLM) rese...
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Fruquintinib has received approval for the management of patients with chemotherapy-resistant metastatic colorectal cancer...
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary intrahepatic mesothelioma (PIHMM) has been rarely reported. Its typical clinical presentation, radiological featur...
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal leiomyosarcoma (CR-LMS) is a rare neoplasm arising from smooth muscle cells. It accounts for less than 0.1% of ...
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
The clinical effectiveness of triple chemotherapy consisting of gemcitabine, cisplatin plus either S-1 (GCS), durvalumab (...
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Hepatocellular carcinoma (HCC) is the most common primary carcinoma arising from the liver. Although HCC can arise de novo...
Temporal Trends in Racial and Gender Disparities of Early Onset Colorectal Cancer in the United States: An Analysis of the CDC WONDER Database
Temporal Trends in Racial and Gender Disparities of Early Onset Colorectal Cancer in the United States: An Analysis of the CDC WONDER Database
The mortality rates of early-onset colorectal cancer (EOCRC) have surged globally over the past two decades. While the und...
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Intrahepatic cholangiocarcinoma is a biliary neoplasm usually showing a dismal prognosis. In early stages, surgical resect...
Efficacy and Safety of Metronomic Capecitabine in Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Efficacy and Safety of Metronomic Capecitabine in Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Metronomic capecitabine has been found to be useful in several types of cancers such as pancreatic cancer, breast cancer, ...
Endoscopic Resection of Stage T1 Colorectal Adenocarcinoma Followed by Surgical Intervention: a Single-center Retrospective Study
Endoscopic Resection of Stage T1 Colorectal Adenocarcinoma Followed by Surgical Intervention: a Single-center Retrospective Study
Domestic and international guidelines recommend endoscopic resection for stage T1 colorectal adenocarcinoma with indicatio...
Association Between Vitamin Intake and Colorectal Cancer: Evidence from NHANES Data
Association Between Vitamin Intake and Colorectal Cancer: Evidence from NHANES Data
This study aims to investigate the associations between vitamins and colorectal cancer (CRC) based on a national sample of...
Outcomes and Prognostic Factors of Patients with Unresectable or Metastatic Esophageal Squamous Cell Carcinoma Undergoing Immunotherapy- Versus Chemotherapy-Based Regimens: Systematic Review and Pooled Analyses
Outcomes and Prognostic Factors of Patients with Unresectable or Metastatic Esophageal Squamous Cell Carcinoma Undergoing Immunotherapy- Versus Chemotherapy-Based Regimens: Systematic Review and Pooled Analyses
Immunotherapy-based regimens (IMT) versus cytotoxic chemotherapy (CHT) improved overall survival (OS) of patients with unr...
Liver Oligometastasis in Biliary Tract Cancer and Impact on Survival Outcomes
Liver Oligometastasis in Biliary Tract Cancer and Impact on Survival Outcomes
Outcomes of unresectable biliary tract cancer (BTC) with varying extents of liver involvement remain unclear. We evaluated...
Can Pretreatment MRI and Planning CT Radiomics Improve Prediction of Complete Pathological Response in Locally Advanced Rectal Cancer Following Neoadjuvant Treatment?
Can Pretreatment MRI and Planning CT Radiomics Improve Prediction of Complete Pathological Response in Locally Advanced Rectal Cancer Following Neoadjuvant Treatment?
The treatment response to neoadjuvant chemoradiation (nCRT) differs largely in individuals treated for rectal cancer. In t...
Percutaneous Metallic Stents in Malignant Biliary Obstruction: Comparison of Nitinol and Wall Stents
Percutaneous Metallic Stents in Malignant Biliary Obstruction: Comparison of Nitinol and Wall Stents
Palliation of malign biliary obstruction is important which is commonly carried out by percutaneous biliary stenting. Our ...
Dynamic Changes in Circulating Methylated Markers in Response to Antitumor Therapy of Rectal Cancer
Dynamic Changes in Circulating Methylated Markers in Response to Antitumor Therapy of Rectal Cancer
Rectal cancer (RC) occupies a leading position in the structure of oncological morbidity and mortality. Aberrant methylati...
Peritoneal Tumour DNA in Peritoneal Fluid: Emerging Tool for Peritoneal Metastasis Detection
Peritoneal Tumour DNA in Peritoneal Fluid: Emerging Tool for Peritoneal Metastasis Detection
The prognostic significance of positive peritoneal cytology still varied between cancer types and geographical origin. How...
Single-Center Randomized Trial Comparing Feeding Jejunostomy with Nasojejunal Tube Placement in Patients Undergoing Transhiatal Esophagectomy Post-Neoadjuvant Therapy for Esophageal Cancer
Single-Center Randomized Trial Comparing Feeding Jejunostomy with Nasojejunal Tube Placement in Patients Undergoing Transhiatal Esophagectomy Post-Neoadjuvant Therapy for Esophageal Cancer
Enteral nutrition is the preferred mode of nutrition following esophagectomy. However, the preferred mode of enteral nutri...
Integrative Bioinformatics Analysis: Unraveling Variant Signatures and Single-Nucleotide Polymorphism Markers Associated with 5-FU-Based Chemotherapy Resistance in Colorectal Cancer Patients
Integrative Bioinformatics Analysis: Unraveling Variant Signatures and Single-Nucleotide Polymorphism Markers Associated with 5-FU-Based Chemotherapy Resistance in Colorectal Cancer Patients
Drug resistance in colorectal cancer (CRC) is modulated by multiple molecular factors, which can be ascertained through ge...
Role of the Clinical Features and MRI Parameters on Ki-67 Expression in Hepatocellular Carcinoma Patients: Development of a Predictive Nomogram
Role of the Clinical Features and MRI Parameters on Ki-67 Expression in Hepatocellular Carcinoma Patients: Development of a Predictive Nomogram
To develop a nomogram using clinical features and the MRI parameters for preoperatively predicting the expression of Ki-67...
Colorectal Adenosquamous Carcinoma: Demographics, Tumor Characteristics, and Survival Benefits of Surgery with Chemoradiation
Colorectal Adenosquamous Carcinoma: Demographics, Tumor Characteristics, and Survival Benefits of Surgery with Chemoradiation
Colorectal adenosquamous carcinoma (ASC) is a rare subtype of colorectal carcinoma. This study presents findings from a la...
Study of Short-Term and Long-Term Outcomes Between Esophagogastrostomy and Double-Tract Reconstruction After Proximal Gastrectomy
Study of Short-Term and Long-Term Outcomes Between Esophagogastrostomy and Double-Tract Reconstruction After Proximal Gastrectomy
As the opportunities for proximal gastrectomy (PG) for early gastric cancer in the upper third stomach have been increasin...
Impact of D2 Total Gastrectomy Including Splenectomy for Scirrhous Gastric Cancer in the Era of Effective Adjuvant Chemotherapy
Impact of D2 Total Gastrectomy Including Splenectomy for Scirrhous Gastric Cancer in the Era of Effective Adjuvant Chemotherapy
Total gastrectomy with D2 dissection including splenectomy (TGS) is usually selected for locally resectable scirrhous gast...
SMARCA4-Deficient Undifferentiated Esophageal Carcinoma: A Clinical Case Series and Literature Review
SMARCA4-Deficient Undifferentiated Esophageal Carcinoma: A Clinical Case Series and Literature Review
Undifferentiated carcinoma of the esophagus (UEC) is a rare malignancy. Deficiency in SMARCA genes, critical for chromatin...
Cachexia Index in Patients with Gastrointestinal Cancer: A Systematic Review and Meta-Analysis
Cachexia Index in Patients with Gastrointestinal Cancer: A Systematic Review and Meta-Analysis
The cachexia index is a novel biomarker of cancer cachexia. This systematic review and meta-analysis aimed to evaluate the...
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