Cancer Statistics. Cancer Information Service, National Cancer Center, Japan (Vital Statistics of Japan, Ministry of Health, Labour and Welfare). https://www.ncc.go.jp/jp/cis/index.html. Accessed on 14 March 2024.

Mine S, Tanaka K, Kawachi H, Shirakawa Y, Kitagawa Y, Toh Y, Yasuda T, Watanabe M, Kamei T, Oyama T, Seto Y, Murakami K, Arai T, Muto M, Doki Y. Japanese classification of esophageal cancer, 12th edition: part I. Esophagus. 2024;21:179–215. https://doi.org/10.1007/s10388-024-01054-y.

Article  PubMed  PubMed Central  Google Scholar 

Kanemura T, Miyata H, Takeoka T, Sugase T, Sugimura K, Yamashita K, Tanaka K, Makino T, Ota M, Yagi K, Toh Y, Seto Y, Doki Y. Significance of dissection in each regional lymph-node station of esophageal cancer based on efficacy index and recurrence patterns after curative esophagectomy. Esophagus. 2023;20:402–9. https://doi.org/10.1007/s10388-022-00977-8.

Article  PubMed  Google Scholar 

Igaue S, Nozaki R, Utsunomiya D, Kubo Y, Kubo K, Kurita D, Yamamoto S, Ishiyama K, Oguma J, Kato K, Daiko H. Significance of surgery for resectable M1 lymph node metastases without organ metastasis in esophageal carcinoma in the era of neoadjuvant treatment. Ann Surg Oncol. 2024;31:1525–35. https://doi.org/10.1245/s10434-023-14562-5.

Article  PubMed  Google Scholar 

Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83. https://doi.org/10.1016/0021-9681(87)90171-8.

Article  CAS  PubMed  Google Scholar 

Versteijne E, van Laarhoven HW, van Hooft JE, van Os RM, Geijsen ED, van Berge Henegouwen MI, Hulshof MC. Definitive chemoradiation for patients with inoperable and/or unresectable esophageal cancer: locoregional recurrence pattern. Dis Esophagus. 2015;28:453–9. https://doi.org/10.1111/dote.12215.

Article  CAS  PubMed  Google Scholar 

Welsh J, Settle SH, Amini A, Xiao L, Suzuki A, Hayashi Y, Hofstetter W, Komaki R, Liao Z, Ajani JA. Failure patterns in patients with esophageal cancer treated with definitive chemoradiation. Cancer. 2012;118:2632–40. https://doi.org/10.1002/cncr.26586.

Article  PubMed  Google Scholar 

Amini A, Ajani J, Komaki R, Allen PK, Minsky BD, Blum M, Xiao L, Suzuki A, Hofstetter W, Swisher S, Gomez D, Liao Z, Lee JH, Bhutani MS, Welsh JW. Factors associated with local-regional failure after definitive chemoradiation for locally advanced esophageal cancer. Ann Surg Oncol. 2014;21:306–14. https://doi.org/10.1245/s10434-013-3303-0.

Article  PubMed  Google Scholar 

Zhu L, Zhao Z, Liu A, Wang X, Geng X, Nie Y, Zhao F, Li M. Lymph node metastasis is not associated with survival in patients with clinical stage T4 esophageal squamous cell carcinoma undergoing definitive radiotherapy or chemoradiotherapy. Front Oncol. 2022;12:774816. https://doi.org/10.3389/fonc.2022.774816.

Article  PubMed  PubMed Central  Google Scholar 

Japan Esophageal Society. Japanese Classification of Esophageal Cancer, 11th Edition: part I. Esophagus. 2017;14:1–36. https://doi.org/10.1007/s10388-016-0551-7.

Article  Google Scholar 

Hsu CP, Hsu NY, Shai SE, Hsia JY, Chen CY. Pre-tracheal lymph node metastasis in squamous cell carcinoma of the thoracic esophagus. Eur J Surg Oncol. 2005;31:749–54. https://doi.org/10.1016/j.ejso.2005.03.009.

Article  CAS  PubMed  Google Scholar 

Zhang N, Gu M, Wang J, Wu S. Comparison of nodal irradiation dose using radiotherapy for patients with thoracic esophageal cancer. Oncol Lett. 2020;19:1042–50. https://doi.org/10.3892/ol.2019.11178.

Article  PubMed  Google Scholar 

Lin WC, Chang CL, Hsu HL, Yuan KS, Wu ATH, Wu SY. Three-dimensional conformal radiotherapy-based or intensity-modulated radiotherapy-based concurrent chemoradiotherapy in patients with thoracic esophageal squamous cell carcinoma. Cancers (Basel). 2019;11:1529. https://doi.org/10.3390/cancers11101529.

Article  CAS  PubMed  Google Scholar 

Morota M, Gomi K, Kozuka T, Chin K, Matsuura M, Oguchi M, Ito H, Yamashita T. Late toxicity after definitive concurrent chemoradiotherapy for thoracic esophageal carcinoma. Int J Radiat Oncol Biol Phys. 2009;75:122–8. https://doi.org/10.1016/j.ijrobp.2008.10.075.

Article  PubMed  Google Scholar