Ogasawara C, Philbrick BD, Adamson DC, Meningioma (2021) A review of Epidemiology, Pathology, Diagnosis, Treatment, and future directions. Biomedicines 9(3):319. https://doi.org/10.3390/biomedicines9030319. PMID: 33801089; PMCID: PMC8004084

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wiemels J, Wrensch M, Claus EB (2010) Epidemiology and etiology of meningioma. J Neurooncol 99(3):307–314. https://doi.org/10.1007/s11060-010-0386-3. Epub 2010 Sep 7. PMID: 20821343; PMCID: PMC2945461

Article  PubMed  PubMed Central  Google Scholar 

Durand A, Labrousse F, Jouvet A, Bauchet L, Kalamaridès M, Menei P, Deruty R, Moreau JJ, Fèvre-Montange M, Guyotat J (2009) WHO grade II and III meningiomas: a study of prognostic factors. J Neurooncol 95(3):367–375. https://doi.org/10.1007/s11060-009-9934-0. Epub 2009 Jun 27. PMID: 19562258

Article  PubMed  Google Scholar 

Walcott BP, Nahed BV, Brastianos PK, Loeffler JS (2013) Radiation treatment for WHO grade II and III meningiomas. Front Oncol 3:227. https://doi.org/10.3389/fonc.2013.00227. PMID: 24032107; PMCID: PMC3759290

Haso S, Bekir R, Džan AJ, Melika D, Amra A, Adi A, Ibrahim O, Ermin H, Hadžan K Clinical and radiologic features in patients with the WHO grade I and II meningiomas. J Health Sci. https://doi.org/10.17532/jhs.2024.2564

Sade B, Chahlavi A, Krishnaney A, Nagel S, Choi E, Lee JH (2007) World Health Organization grades II and III meningiomas are rare in the cranial base and spine. Neurosurgery 61(6):1194-8; discussion 1198. https://doi.org/10.1227/01.neu.0000306097.38141.65. PMID: 18162898

El-Hajj VG, Edström E, Elmi-Terander A (2023) High grade spinal meningiomas: a rare but formidable challenge. Transl Cancer Res 12(7):1649–1651. https://doi.org/10.21037/tcr-23-740. Epub 2023 Jun 20. PMID: 37588730; PMCID: PMC10425664

Article  PubMed  PubMed Central  Google Scholar 

Zhou P, Ma W, Yin S, Li Y, Jiang S (2013) Jan-Feb;61(1):40 – 4 Three risk factors for WHO grade II and III meningiomas: A study of 1737 cases from a single center. Neurol India. https://doi.org/10.4103/0028-3886.107928. PMID: 23466838

Kessel KA, Fischer H, Oechnser M, Zimmer C, Meyer B, Combs SE (2017) High-precision radiotherapy for meningiomas: Long-term results and patient-reported outcome (PRO). Strahlenther Onkol 193(11):921–930 English. https://doi.org/10.1007/s00066-017-1156-3

Article  PubMed  Google Scholar 

Adeberg S, Hartmann C, Welzel T, Rieken S, Habermehl D, von Deimling A, Debus J, Combs SE (2012) Long-term outcome after radiotherapy in patients with atypical and malignant meningiomas–clinical results in 85 patients treated in a single institution leading to optimized guidelines for early radiation therapy. Int J Radiat Oncol Biol Phys 83(3):859–864. Epub 2011 Dec 2. PMID: 22137023

Article  PubMed  Google Scholar 

Ehret F, El Baya L, Erridge SC, Bussière M, Verhoeff JJC, Niyazi M, Preusser M, Minniti G, Shih HA (2025) Radiation therapy for Meningiomas - Where do we stand and what’s on the horizon? Int J Radiat Oncol Biol Phys 121(3):599–612. Epub 2024 Oct 28. PMID: 39476990

Article  PubMed  Google Scholar 

Combs SE, Farzin M, Boehmer J, Oehlke O, Molls M, Debus J, Grosu AL (2018) Clinical outcome after high-precision radiotherapy for skull base meningiomas: Pooled data from three large German centers for radiation oncology. Radiother Oncol 127(2):274–279. https://doi.org/10.1016/j.radonc.2018.03.006. Epub 2018 Mar 26. PMID: 29598834

El Shafie RA, Czech M, Kessel KA, Habermehl D, Weber D, Rieken S, Bougatf N, Jäkel O, Debus J, Combs SE (2018) Clinical outcome after particle therapy for meningiomas of the skull base: toxicity and local control in patients treated with active Rasterscanning. Radiat Oncol 13(1):54. https://doi.org/10.1186/s13014-018-1002-5. PMID: 29587795; PMCID: PMC5870393

Article  CAS  PubMed  PubMed Central  Google Scholar 

Combs SE, Welzel T, Habermehl D, Rieken S, Dittmar JO, Kessel K, Jäkel O, Haberkorn U, Debus J (2013) Prospective evaluation of early treatment outcome in patients with meningiomas treated with particle therapy based on target volume definition with MRI and 68Ga-DOTATOC-PET. Acta Oncol 52(3):514–520. Epub 2013 Feb 12. PMID: 23402336

Article  CAS  PubMed  Google Scholar 

Patel B, Desai R, Pugazenthi S, Butt OH, Huang J, Kim AH (2022) Identification and management of aggressive meningiomas. Front Oncol 12:851758. https://doi.org/10.3389/fonc.2022.851758. Erratum in: Front Oncol. 2022;12:1107271. https://doi.org/10.3389/fonc.2022.1107271. PMID: 35402234; PMCID: PMC8984123

Combs SE, Baumert BG, Bendszus M, Bozzao A, Brada M, Fariselli L, Fiorentino A, Ganswindt U, Grosu AL, Lagerwaard FL, Niyazi M, Nyholm T, Paddick I, Weber DC, Belka C, Minniti G (2021) ESTRO ACROP guideline for target volume delineation of skull base tumors. Radiother Oncol 156:80–94. Epub 2020 Dec 10. PMID: 33309848

Article  PubMed  Google Scholar 

Weber DC, Bizzocchi N, Bolsi A, Jenkinson MD (2020) Proton therapy for intracranial meningioma for the treatment of Primary/Recurrent disease including Re-Irradiation. Front Oncol 10:558845. https://doi.org/10.3389/fonc.2020.558845. PMID: 33381447; PMCID: PMC7769250

Article  PubMed  PubMed Central  Google Scholar 

Combs SE, Hartmann C, Nikoghosyan A, Jäkel O, Karger CP, Haberer T, von Deimling A, Münter MW, Huber PE, Debus J, Schulz-Ertner D (2010) Carbon ion radiation therapy for high-risk meningiomas. Radiother Oncol 95(1):54–59. Epub 2010 Feb 25. PMID: 20189258

Article  CAS  PubMed  Google Scholar 

Weber DC, Ares C, Villa S, Peerdeman SM, Renard L, Baumert BG, Lucas A, Veninga T, Pica A, Jefferies S, Ricardi U, Miralbell R, Stelmes JJ, Liu Y, Collette L, Collette S (2018) Adjuvant postoperative high-dose radiotherapy for atypical and malignant meningioma: A phase-II parallel non-randomized and observation study (EORTC 22042–26042). Radiother Oncol 128(2):260–265. https://doi.org/10.1016/j.radonc.2018.06.018. Epub 2018 Jun 28. PMID: 29960684

Article  PubMed  Google Scholar 

Rogers CL, Won M, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Galvin J, Fogh SE, Youssef E, Deb N, Kwok Y, Robinson CG, Shu HK, Fisher BJ, Panet-Raymond V, McMillan WG, de Groot JF, Zhang P, Mehta MP (2020) High-risk meningioma: initial outcomes from NRG Oncology/RTOG 0539. Int J Radiat Oncol Biol Phys 106(4):790–799. Epub 2019 Nov 29. PMID: 31786276; PMCID: PMC7117785

Article  PubMed  Google Scholar 

Yoon H, Mehta MP, Perumal K, Helenowski IB, Chappell RJ, Akture E, Lin Y, Marymont MA, Sejpal S, Parsa A, Chandler JR, Bendok BR, Rosenow J, Salamat S, Kumthekar P, Raizer JK, Baskaya MK (2015) Jan-Mar;11(1):59–66 Atypical meningioma: randomized trials are required to resolve contradictory retrospective results regarding the role of adjuvant radiotherapy. J Cancer Res Ther. https://doi.org/10.4103/0973-1482.148708. PMID: 25879338

Deng MY, Maas SLN, Hinz F, Karger CP, Sievers P, Eichkorn T, Meixner E, Hoegen-Sassmannshausen P, Hörner-Rieber J, Lischalk JW, Seidensaal K, Bernhardt D, Jungk C, Unterberg A, Wick A, Wick W, von Deimling A, Sahm F, Combs S, Herfarth K, Debus J, König L (2024) Efficacy and toxicity of bimodal radiotherapy in WHO grade 2 meningiomas following subtotal resection with carbon ion boost: prospective phase 2 MARCIE trial. Neuro Oncol 26(4):701–712. https://doi.org/10.1093/neuonc/noad244. PMID: 38079455; PMCID: PMC10995516

Article  CAS  PubMed  Google Scholar 

Rogers L, Barani I, Chamberlain M, Kaley TJ, McDermott M, Raizer J, Schiff D, Weber DC, Wen PY, Vogelbaum MA (2015) Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg 122(1):4–23 PMID: 25343186; PMCID: PMC5062955

Article  PubMed  PubMed Central  Google Scholar 

Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M (2021) EANO guideline on the diagnosis and management of meningiomas. Neuro Oncol 23(11):1821–1834. https://doi.org/10.1093/neuonc/noab150. PMID: 34181733; PMCID: PMC8563316

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu A, Jin MC, Meola A, Wong HN, Chang SD (2019) Efficacy and toxicity of particle radiotherapy in WHO grade II and grade III meningiomas: A systematic review. Neurosurg Focus 46(6):E12. https://doi.org/10.3171/2019.3.FOCUS1967. PMID: 31153145

Sreenivasan S, Najjar S, Ma D, Begley SL, Wuu YR, Rana Z, Gogineni E, Schulder M, Goenka A (2025) Exploring the role of radiosurgery for atypical meningiomas: addressing suboptimal local control in high-risk patients. Adv Radiat Oncol 10(3):101709 PMID: 39949525; PMCID: PMC11821406

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sahm F, Schrimpf D, Stichel D, Jones DTW, Hielscher T, Schefzyk S, Okonechnikov K, Koelsche C, Reuss DE, Capper D, Sturm D, Wirsching HG, Berghoff AS, Baumgarten P, Kratz A, Huang K, Wefers AK, Hovestadt V, Sill M, Ellis HP, Kurian KM, Okuducu AF, Jungk C, Drueschler K, Schick M, Bewerunge-Hudler M, Mawrin C, Seiz-Rosenhagen M, Ketter R, Simon M, Westphal M, Lamszus K, Becker A, Koch A, Schittenhelm J, Rushing EJ, Collins VP, Brehmer S, Chavez L, Platten M, Hänggi D, Unterberg A, Paulus W, Wick W, Pfister SM, Mittelbronn M, Preusser M, Herold-Mende C, Weller M, von Deimling A (2017) DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. Lancet Oncol 18(5):682–694. https://doi.org/10.1016/S1470-2045(17)30155-9. Epub 2017 Mar 15. PMID: 28314689

Article  CAS  PubMed  Google Scholar 

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol 23(8):1231–1251. https://doi.org/10.1093/neuonc/noab106. PMID: 34185076; PMCID: PMC8328013

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang JZ, Landry AP, Raleigh DR, Sahm F, Walsh KM, Goldbrunner R, Yefet LS, Tonn JC, Gui C, Ostrom QT, Barnholtz-Sloan J, Perry A, Ellenbogen Y, Hanemann CO, Jungwirth G, Jenkinson MD, Tabatabai G, Mathiesen TI, McDermott MW, Tatagiba M, la Fougère C, Maas SLN, Galldiks N, Albert NL, Brastianos PK, Ehret F, Minniti G, Lamszus K, Ricklefs FL, Schittenhelm J, Drummond KJ, Dunn IF, Pathmanaban ON, Cohen-Gadol AA, Sulman EP, Tabouret E, Le Rhun E, Mawrin C, Moliterno J, Weller M, Bi WL, Gao A, Yip S, Niyazi M, Aldape K, Wen PY, Short S, Preusser M, Nassiri F, Zadeh G (2024) Meningioma: international consortium on meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients. Neuro Oncol 26(10):1742–1780 International Consortium on Meningiomas (ICOM). https://doi.org/10.1093/neuonc/noae082

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dittmar JO, Kratochwil C, Dittmar A, Welzel T, Habermehl D, Rieken S, Giesel FL, Haberkorn U, Debus J, Combs SE (2017) First intraindividual comparison of contrast-enhanced MRI, FET- and DOTATOC- PET in patients with intracranial meningiomas. Radiat Oncol 12(1):169. https://doi.org/10.1186/s13014-017-0913-x. PMID: 29110720; PMCID: PMC5674744

Article  CAS  PubMed  PubMed Central  Google Scholar