Withers PC, Cooper CE, Maloney SK, Bozinovic F, Cruz-Neto AP. Ecological and environmental physiology of mammals. Oxford: Oxford University Press; 2016.
Ravussin E, Lillioja S, Knowler WC, Christin L, Freymond D, Abbott WG, et al. Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med. 1988;318:467–72.
Article PubMed CAS Google Scholar
Hohenadel MG, Hollstein T, Thearle M, Reinhardt M, Piaggi P, Salbe AD, et al. A low resting metabolic rate in late childhood is associated with weight gain in adolescence. Metabolism. 2019;93:68–74.
Article PubMed PubMed Central CAS Google Scholar
Speakman JR, de Jong JMA, Sinha S, Westerterp KR, Yamada Y, Sagayama H, et al. Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure. Nat Metab. 2023;5:579–88.
Article PubMed PubMed Central Google Scholar
Landsberg L, Young JB, Leonard WR, Linsenmeier RA, Turek FW. Is obesity associated with lower body temperatures? Core temperature: a forgotten variable in energy balance. Metab Clin Exp. 2009;58:871–6.
Article PubMed CAS Google Scholar
Dulloo AG, Schutz Y. Adaptive thermogenesis in resistance to obesity therapies: issues in quantifying thrifty energy expenditure phenotypes in humans. Curr Obes Rep. 2015;4:230–40.
Reinhardt M, Schlögl M, Bonfiglio S, Votruba SB, Krakoff J, Thearle MS. Lower core body temperature and greater body fat are components of a human thrifty phenotype. Int J Obes. 2016;40:754–60.
Clarke A, Rothery P, Isaac NJ. Scaling of basal metabolic rate with body mass and temperature in mammals. J Anim Ecol. 2010;79:610–9.
Uyeda JC, Bone N, McHugh S, Rolland J, Pennell MW. How should functional relationships be evaluated using phylogenetic comparative methods? A case study using metabolic rate and body temperature. Evolution. 2021;75:1097–105.
Rising R, Keys A, Ravussin E, Bogardus C. Concomitant interindividual variation in body temperature and metabolic rate. Am J Physiol. 1992;263:E730–4.
Willershäuser M, Ehrhardt N, Elvert R, Wirth EK, Schweizer U, Gailus-Durner V, et al. Systematic screening for mutant mouse lines with defects in body temperature regulation. In: Ruf T, Bieber C, Arnold W, Millesi E, editors. Living in a seasonal world. Berlin Heidelberg: Springer-Verlag; 2012. pp. 459–69.
Piaggi P. Metabolic determinants of weight gain in humans. Obesity. 2019;27:691–9.
Hollstein T, Heinitz S, Ando T, Rodzevik TL, Basolo A, Walter M, et al. Metabolic responses to 24-hour fasting and mild cold exposure in overweight individuals are correlated and accompanied by changes in FGF21 concentration. Diabetes. 2020;69:1382–8.
Article PubMed PubMed Central Google Scholar
Boratyński JS, Szafrańska PA. Does basal metabolism set the limit for metabolic downregulation during torpor?. Physiol Biochem Zool. 2018;91:1057–67.
Gordon CJ. The mouse: an “average” endotherm. J Therm Biol. 2012;37:286–90.
Gordon CJ. Thermal physiology of laboratory mice: defining thermoneutrality. J Therm Biol. 2012;37:654–85.
Gordon CJ. The mouse thermoregulatory system: its impact on translating biomedical data to humans. Physiol Behav. 2017;179:55–66.
Article PubMed PubMed Central CAS Google Scholar
Zhao Z, Yang R, Li M, Bao M, Huo D, Cao J, et al. Effects of ambient temperatures between 5 and 35 °C on energy balance, body mass and body composition in mice. Mol Metab. 2022;64:101551.
Article PubMed PubMed Central CAS Google Scholar
Reitman ML. Of mice and men – environmental temperature, body temperature, and treatment of obesity. FEBS Lett. 2018;592:2098–107.
Article PubMed CAS Google Scholar
Książek A, Konarzewski M, Łapo IB. Anatomic and energetic correlates of divergent selection for basal metabolic rate in laboratory mice. Physiol Biochem Zool. 2004;77:890–9.
Gębczyński AK, Konarzewski M. Locomotor activity of mice divergently selected for basal metabolic rate: a test of hypotheses on the evolution of endothermy. J Exp Biol. 2009;22:1212–20.
Gębczyński AK, Sadowska J, Konarzewski M. Differences in the range of thermoneutral zone between mouse strains: potential effects on translational research. Am J Physiol Regul Integr Comp Physiol. 2024;326:R91–9.
Garland T Jr, Rose MR. Experimental evolution. Concepts, methods and applications of selection experiments. Berkeley and Los Angeles: University of California Press; 2009.
Brzęk P, Gębczyński A, Selewestruk P, Książek A, Sadowska J, Konarzewski M. Significance of variation in basal metabolic rate in laboratory mice for translational experiments. J Comp Physiol B. 2022;192:161–9.
Brzęk P, Selewestruk P, Sadowska J, Gębczyński AK, Książek A, Kalinovich A, et al. Divergent selection for basal metabolic rate in laboratory mice affects the abundance of UCP1 protein: implications for translational studies. J Physiol. 2025;603:319–36.
Brzęk P, Książek A, Dobrzyń A, Konarzewski M. Effect of dietary restriction on metabolic, anatomic and molecular traits in mice depends on the initial level of basal metabolic rate. J Exp Biol. 2012;215:3191–9.
Sadowska J, Gębczyński AK, Konarzewski M. Metabolic risk factors in mice divergently selected for BMR fed high fat and high carb diets. PLoS ONE. 2017;12:e0172892.
Article PubMed PubMed Central Google Scholar
Gębczyński AK. Nonshivering thermogenesis capacity versus basal metabolic rate in laboratory mice. J Therm Biol. 2008;33:250–4.
Henderson ND. Interpreting studies that compare high- and low-selected lines on new characters. Behav Genet. 1989;19:473–502.
Article PubMed CAS Google Scholar
Henderson ND. Spurious associations in unreplicated selected lines. Behav Genet. 1997;27:145–54.
Article PubMed CAS Google Scholar
Konarzewski M, Książek A, Łapo IB. Artificial selection on metabolic rates and related traits in rodents. Integr Comp Biol. 2005;45:416–25.
Brzęk P, Roussel D, Konarzewski M. Mice selected for a high basal metabolic rate evolved larger guts but not more efficient mitochondria. Proc R Soc B. 2022;289:20220719.
Article PubMed PubMed Central Google Scholar
Falconer DS, Mackay TFC. Introduction to quantitative genetics. 4th ed. Essex: Lognman;1996.
Connolly MS, Lynch CB. Circadian variation of strain differences in body temperature and activity in mice. Physiol Behav. 1981;27:1045–9.
Article PubMed CAS Google Scholar
Connolly MS, Lynch CB. Classical genetic analysis of circadian body temperature rhythms in mice. Behav Genet. 1983;13:491–500.
Article PubMed CAS Google Scholar
Lynch CB, Sulzbach DS. Quantitative genetic analysis of temperature regulation in Mus musculus. II. Diallel analysis of individual traits. Evolution. 1983;38:527–40.
Lynch CB, Sulzbach DS, Connolly MS. Quantitative-genetic analysis of temperature regulation in Mus domesticus. IV. Pleiotropy and genotype-by-environment interactions. Am Nat. 1988;132:521–37.
Landsberg L. Core temperature: a forgotten variable in energy expenditure and obesity?. Obes Rev. 2012;13:S97–S104.
Abreu-Vieira G, Xiao C, Gavrilova O, Reitman ML. Integration of body temperature into the analysis of energy expenditure in the mouse. Mol Metab. 2015;4:461–70.
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