The clinical and economic burden of obesity in low- and middle-income countries: a systematic review

World Health Organisation Obesity: preventing and managing the global epidemic (Report of a WHO Consultation: WHO Technical Report Series 894). Geneva: World Health Organisation; 2000.

Google Scholar 

Ataey A, Jafarvand E, Adham D, Moradi-Asl E. The relationship between obesity, overweight, and the human development index in world health organisation eastern mediterranean region countries. J Prev Med Public Health. 2020;53:98.

Article  PubMed  PubMed Central  Google Scholar 

WHO. Obesity and overweight. 2016. http://www.who.int/mediacentre/factsheets/fs311/en/. WHO. Obesity and overweight. 2020. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.

Ahmed SK. Mohammed RA. Obesity: prevalence, causes, consequences, management, preventive strategies and future research directions. Metab Open. 2025;27:100375

Article  Google Scholar 

World Health Organisation. Obesity and overweight. 2015. http://www.who.int/mediacentre/factsheets/fs311/en/.

Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–81.

Article  PubMed  PubMed Central  Google Scholar 

NCD Risk Factor Collaboration. Trends in adult body-mass index in 200 countries from 1975–2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387:1377–96.

Article  Google Scholar 

Balarajan Y, Villamor E. Nationally representative surveys show recent increases in the prevalence of overweight and obesity among women of reproductive age in Bangladesh, Nepal, and India. J Nutr. 2009;139:2139–44.

Article  PubMed  CAS  Google Scholar 

Fan H, Zhang X. Recent trends in overweight and obesity in adolescents aged 12 to 15 years across 21 countries. Pediatr Obes. 2022;17:e12839.

Article  PubMed  Google Scholar 

Mamun AA, Finlay JE. Shifting of undernutrition to overnutrition and its determinants among women of reproductive ages in the 36 low to medium income countries. Obes Res Clin Pract. 2015;9:75–86. https://doi.org/10.1016/j.orcp.2014.03.001.

Article  PubMed  Google Scholar 

Leocádio PCL, Lopes SC, Dias RP, Alvarez-Leite JI, Guerrant RL, Malva JO, et al. The transition from undernutrition to overnutrition under adverse environments and poverty: the risk for chronic diseases. Front Nutr. 2021;8:676044.

Article  PubMed  PubMed Central  Google Scholar 

Keino BC, Carrel M. Spatial and temporal trends of overweight/obesity and tobacco use in East Africa: subnational insights into cardiovascular disease risk factors. Int J Health Geogr. 2023;22:20.

Article  PubMed  PubMed Central  Google Scholar 

Jaacks LM, Slining MM, Popkin BM. Recent underweight and overweight trends by rural-urban residence among women in low- and middle-income countries. J Nutr. 2015;145:352–7.

Article  PubMed  CAS  Google Scholar 

GBD 2021 Adolescent BMI Collaborators. Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021. Lancet. 2025;405:785–812.

Article  Google Scholar 

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet. 2024;403:1027–50.

Article  Google Scholar 

Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity. JAMA. 2003;289:187–93.

Article  PubMed  Google Scholar 

Peeters A, Barendregt JJ, Willekens F, Mackenbach JP, Al Mamun A, Bonneux L. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med. 2003;138:24–32.

Article  PubMed  Google Scholar 

Klages KL, Berlin KS, Cook JL, Merchant TE, Wise MS, Mandrell BN, et al. Health-related quality of life, obesity, fragmented sleep, fatigue, and psychosocial problems among youth with craniopharyngioma. Psychooncology. 2022;31:779–87.

Article  PubMed  Google Scholar 

Peeters A, Barendregt JJ, Willekens F, Mackenbach JP, Al Mamun A, Bonneux L. NEDCOM, the Netherlands Epidemiology and Demography Compression of Morbidity Research Group. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med. 2003;138:24–32.

Article  PubMed  Google Scholar 

Saker Z, Saab M, Rabah A. The impact of body mass index on the duration of hospital stay after cardiac surgery. Cureus. 2025;17:e84985.

PubMed  PubMed Central  Google Scholar 

Wang J, Huang Y, Feng N, Xu L, Du X, Chen M, et al. Global disease burden attributable to high body mass index in young adults from 1990 to 2019, with projections to 2050: a systematic analysis for the Global Burden of Disease Study 2019. Diabetes Metab Res Rev. 2024;40:e70007.

Article  PubMed  Google Scholar 

Tremmel M, Gerdtham UG, Nilsson PM, Saha S. Economic burden of obesity: a systematic literature review. Int J Environ Res Public Health. 2017;14:435.

Article  PubMed  PubMed Central  Google Scholar 

Withrow D, Alter DA. The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obes Rev. 2011;12:131–41.

Article  PubMed  CAS  Google Scholar 

Specchia ML, Veneziano MA, Cadeddu C, Ferriero AM, Mancuso A, Ianuale C, et al. Economic impact of adult obesity on health systems: a systematic review. Eur J Public Health. 2015;25:255–62.

Article  PubMed  Google Scholar 

Nagi MA, Ahmed H, Rezq MA, Sangroongruangsri S, Chaikledkaew U, Almalki Z, et al. Economic costs of obesity: a systematic review. Int J Obes. 2024;48:33–43.

Article  Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151:264–9.

Article  PubMed  Google Scholar 

Wells GA, Tugwell P, O’Connell D, Welch V, Peterson J, Shea B, et al. The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2015. https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp.

The World Bank. GDP deflator. 2023. https://data.worldbank.org/indicator/NY.GDP.DEFL.ZS.

The World Bank. Official exchange rate. 2023. https://data.worldbank.org/indicator/PA.NUS.FCRF.

Kudel I, Alves JS, de Menezes Goncalves T, Kull K, Nørtoft E. The association between body mass index and health and economic outcomes in Brazil. Diabetol Metab Syndr. 2018;10:1–11.

Article  Google Scholar 

Li Q, Cai L, Cui W, Wang G, He J, Golden AR. Economic burden of obesity and four obesity-related chronic diseases in rural Yunnan Province, China. Public Health. 2018;164:91–8.

Article  PubMed  CAS  Google Scholar 

Pitayatienanan P, Butchon R, Yothasamut J, Aekplakorn W, Teerawattananon Y, Suksomboon N, et al. Economic costs of obesity in Thailand: a retrospective cost-of-illness study. BMC Health Serv Res. 2014;14:146.

Article  PubMed  PubMed Central  Google Scholar 

Bahia L, Coutinho ESF, Barufaldi LA, de Azevedo Abreu G, Malhão TA, Ribeiro de Souza CP, et al. The costs of overweight and obesity-related diseases in the Brazilian public health system: cross-sectional study. BMC Public Health. 2012;12:1–7.

Article  Google Scholar 

Lartey S, Si L, Lung T, Magnussen CG, Boateng GO, Minicuci N, et al. Impact of overweight and obesity on life expectancy, quality-adjusted life years and lifetime costs in the adult population of Ghana. BMJ Glob Health. 2020;5:e003332.

Article  PubMed  PubMed Central  Google Scholar 

Boachie MK, Thsehla E, Immurana M, Kohli-Lynch C, Hofman KJ. Estimating the healthcare cost of overweight and obesity in South Africa. Glob Health Action. 2022;15:2045092.

Article  PubMed  PubMed Central  Google Scholar 

Shi J, Wang Y, Cheng W, Shao H, Shi L. Direct health care costs associated with obesity in Chinese population in 2011. J Diabetes Complications. 2017;31:523–8.

Article  PubMed  Google Scholar 

de Oliveira ML, Santos LMP, da Silva EN. Direct healthcare cost of obesity in Brazil: an application of the cost-of-illness method from the perspective of the public health system in 2011. PLoS ONE. 2015;10:e0121160.

Article  PubMed  PubMed Central  Google Scholar 

Rtveladze K, Marsh T, Webber L, Kilpi F, Levy D, Conde W, et al. Health and economic burden of obesity in Brazil. PLoS ONE. 2013;8:e68785.

Article  PubMed 

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